SAFE TRACHEOSTOMY IN HEAD AND NECK CARCINOMA PATIENTS DURING COVID ERA: METHOD AND DEMOGRAPHICS

Introduction: Tracheostomy is inevitable in the management of many head and neck malignancy. The indications vary from supportive to palliative. During Covid-19 era, ensuring surgeon safety while performing tracheostomy is of utmost importance as tracheostomy is considered an aerosol generating procedure. Materials and methods: All the patients who underwent tracheostomy as part of the management of carcinoma of head and neck region in the department of Surgical Oncology from March till October 2020 Conclusion: Following proper safety measures while doing tracheostomy will ensure safety of the surgeon.

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Elevated Serum Secretory Immunoglobulin a Levels in Patients with Head and Neck Carcinoma

Otolaryngology ◽

10.1177/019459988309100205 ◽

1983 ◽

Vol 91 (2) ◽

pp. 136-142 ◽

Cited By ~ 8

Author(s):

Tsuneo Watanabe ◽

J. Dirk Iglehart ◽

Dani P. Bolognesi ◽

Edwin B. Cox ◽

Anna Vaughn ◽

...

Keyword(s):

Head And Neck ◽

Immunoglobulin A ◽

Elevated Serum ◽

Neck Region ◽

Head And Neck Carcinoma ◽

Secretory Immunoglobulin A ◽

Diagnostic Significance ◽

Head And Neck Region ◽

Neck Carcinoma ◽

Secretory Immunoglobulin

Secretory immunoglobulin A (SlgA) is a major component of the secretory immune system and has been demonstrated in the sera of patients with various pathologic conditions. Current studies were undertaken to quantitate secretory components (SC) in sera of patients with squamous cell carcinoma in the head and neck region by means of a sensitive double-antibody radioimmunoassay. Patients with head and neck carcinoma were found to have threefold higher levels of SC (1.54 ± 0.74 mg/ml) compared to normal controls (0.51 ± 0.22mg/ml, P < .0001). Of interest was that the sera of patients who had successfully been treated 2 to 6 months prior to the study demonstrated statistically lower levels than those of patients with untreated carcinoma or recurrent disease. SC in sera appears to be in the form of SlgA. The origin and diagnostic significance of SC are briefly discussed.

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Long Non-coding RNAs as Important Biomarkers in Laryngeal Cancer and Other Head and Neck Tumours

International Journal of Molecular Sciences ◽

10.3390/ijms20143444 ◽

2019 ◽

Vol 20 (14) ◽

pp. 3444 ◽

Cited By ~ 18

Author(s):

Alessia Maria Cossu ◽

Laura Mosca ◽

Silvia Zappavigna ◽

Gabriella Misso ◽

Marco Bocchetti ◽

...

Keyword(s):

Head And Neck ◽

Laryngeal Cancer ◽

Neck Region ◽

Head And Neck Carcinoma ◽

Molecular Signatures ◽

Head And Neck Tumours ◽

Head And Neck Region ◽

Neck Carcinoma ◽

Non Coding Rnas ◽

Pharmacological Application

Head and neck carcinoma (HNC) is a heterogeneous disease encompassing a variety of tumors according to the origin. Laryngeal cancer (LC) represents one of the most frequent tumors in the head and neck region. Despite clinical studies and advance in treatment, satisfactory curative strategy has not yet been reached. Therefore, there is an urgent need for the identification of specific molecular signatures that better predict the clinical outcomes and markers that serve as suitable therapeutic targets. Long non-coding RNAs (lncRNA) are reported as important regulators of gene expression and represent an innovative pharmacological application as molecular biomarkers in cancer. The purpose of this review is to discuss the most relevant epigenetic and histological prognostic biomarkers in HNC, with particular focus on LC. We summarize the emerging roles of long non-coding RNAs in HNC and LC development and their possible use in early diagnosis.

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The repair of defects in the head and neck region with the latissimus dorsi myocutaneous flap

The Journal of Laryngology & Otology ◽

10.1017/s0022215100107510 ◽

1988 ◽

Vol 102 (12) ◽

pp. 1127-1132 ◽

Cited By ~ 8

Author(s):

C. R. Chowdhury ◽

N. R. Mclean ◽

K. Harrop-Griffiths ◽

N. M. Breach

Keyword(s):

Head And Neck ◽

Latissimus Dorsi ◽

Myocutaneous Flap ◽

Neck Region ◽

Head And Neck Reconstruction ◽

Head And Neck Region ◽

Neck Malignancy ◽

Latissimus Dorsi Myocutaneous Flap ◽

Microvascular Flap ◽

Fistula Rate

AbstractThere are many different flaps available for head and neck reconstruction. The latissimus dorsi myocutaneous flap has been widely used in this unit on 80 occasions in the past three years, both as a pedicled and as a free microvascular flap following the excision of head and neck malignancy, the commonest pathology being intraoral squamous cell carcinoma.There were nine cases of complete or substantial flap loss requiring a further reconstructive procedure. Few of the patients who underwent total glossectomy suffered from overspill or aspiration and the fistula rate was low.Reference is made to the anatomy and the technique of raising this versatile flap which provides a large volume of tissue and has been particularly useful following total glossesctomy when combined with a hyoid hitch.

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Bronchoscopy in the Staging and Evaluation of Head and Neck Carcinoma

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348948309200416 ◽

1983 ◽

Vol 92 (4) ◽

pp. 373-376 ◽

Cited By ~ 12

Author(s):

Bruce Leipzig

Keyword(s):

Head And Neck ◽

Squamous Cell ◽

Neck Region ◽

Head And Neck Carcinoma ◽

Tracheobronchial Tree ◽

Squamous Cell Carcinomas ◽

Chest Radiographs ◽

Upper Aerodigestive Tract ◽

Neck Carcinoma ◽

The Face

There is no consensus of opinion regarding the use of routine bronchoscopy, either rigid or flexible, to evaluate patients with primary squamous cell carcinomas of the upper aerodigestive tract for the possibility of second synchronous primary cancers. Whereas there is certainty of the effectiveness of this endoscopy in patients with questionable lesions or masses on chest radiographs, the value of this procedure in the face of a normal, unequivocal chest radiograph remains questionable. Six patients with primary carcinomas in the upper head and neck region and normal chest radiographs were among 98 patients evaluated within the past 6 months by triple endoscopy. In three instances, a small (less than 2 cm) lesion was discovered in the tracheobronchial tree, utilizing rigid diagnostic bronchoscopy. In three other patients with positive cytology from bronchial washings, a lung primary carcinoma has not been discovered. These presumed false-positive findings add a watchword of warning. The observation of these patients provides evidence to support the routine panendoscopic evaluation of all patients with squamous cell carcinomas of the head and neck. A valid study to identify subgroups at risk to develop these cancers should be encouraged.

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Radiation-induced Fibrosarcoma of the Larynx: a Case Report and Review of Literature

10.21203/rs.3.rs-570162/v1 ◽

2021 ◽

Author(s):

Wei Gong ◽

Donghai Huang

Keyword(s):

Head And Neck ◽

Surgical Resection ◽

Rare Complication ◽

Neck Region ◽

Head And Neck Carcinoma ◽

Malignant Tumour ◽

Primary Treatment ◽

Head And Neck Region ◽

Complete Surgical Resection ◽

Radiation Induced

Abstract Background: Radiation-induced sarcoma (RIS) is a rare complication following radiotherapy of head and neck carcinoma. It occurs mostly within the limits of the irradiated area and always suggests a poor prognosis. Case summary: Herein, we reported one case of a 61-year-old male with laryngeal squamous cell carcinoma (SCC), who had a history of surgery and radiotherapy. In 2014, this patient was admitted in our hospital for increasing hoarseness five years after surgery and radiotherapy. Finally, the patient was diagnosed as fibrosarcoma and was given total laryngectomy, the patient was died in August 2019 within following up. In addition, the clinical and pathological characteristics of similar cases and their probable tumorgenesis were also reviewed. Conclusion: RIS is increasingly important. They usually occur mostly within the limits of the irradiated area. SCC is the most common malignant tumour in the head and neck region, and radiotherapy is a primary adjuvant therapy method. For patients receiving radiotherapy, physicians should follow up more carefully for early detection the RISs. For sarcomas occurring in head and neck region, especially RIS, complete surgical resection is the primary treatment. The choice of radiotherapy and chemotherapy should be more cautious. The prognosis of primary sarcomas or RISs is still controversial. No matter primary sarcomas or RISs, we believe that complete surgical resection should be considered as a top priority in surgery.

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Simultaneous occurrence of metastatic tonsillar squamous cell carcinoma and angioimmunoblastic T-cell lymphoma in a cervical lymph node

The Journal of Laryngology & Otology ◽

10.1017/s0022215100137971 ◽

1997 ◽

Vol 111 (6) ◽

pp. 580-582 ◽

Cited By ~ 4

Author(s):

W. Habermann ◽

W. Anderhuber ◽

U. Humer-Fuchst ◽

H. Stammberger

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Head And Neck Carcinoma ◽

Simultaneous Occurrence ◽

Tonsillar Carcinoma ◽

Neck Malignancy ◽

Neck Carcinoma ◽

Tonsillar Squamous Cell Carcinoma

AbstractNon-Hodgkin's lymphoma (NHL) is a frequent head and neck malignancy. Squamous cell carcinoma of the tonsil is the second most common head and neck carcinoma. We report a case of a tonsillar carcinoma metastasis in an angioimmunoblastic-transformedlymph node. To our knowledge this is the first description and histopathological documentation of such a case in the literature.

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