scholarly journals Treatment of Medial Canthal Tumor by Rotation Flap

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Qirat Qurban ◽  
Zeeshan Kamil ◽  
Khalid Mahmood
Keyword(s):  
Case Series ◽  
Previous Treatment ◽  
Cosmetic Outcome ◽  
Ethical Review ◽  
Review Committee ◽  
Medial Canthus ◽  
Rotation Flap ◽  
Ethical Review Committee ◽  
Surrounding Skin

Purpose:  To describe the cosmetic outcome after repairing medial canthal defects via glabellar rotation flaps in patients undergoing wide clear margin excision of medial canthal tumour. Study Design:  Interventional case series. Place and Duration of Study:  This study was conducted at Khalid Eye Clinic, Nazimabad, Karachi, from March 2019 to August 2019. Methods:  Study approval was obtained from the Ethical Review Committee. Eleven patients of both genders with clinically suspected medial canthal tumor were included in the study. Patients who underwent previous treatment such as radiation, cryotherapy or surgery were excluded. All surgeries were done to remove the tumor along with surrounding wide clear margins followed by reconstruction of the defect of the medial canthusareawith the help of arotation flap. Patients were followed for a period of up to six months post operatively for any wound related problems or recurrence. All patients were informed about the study and consent was obtained from each of them. Results:  All eleven patients of this study were satisfied at the end of the follow-up period with the final cosmetic outcome. Seven out of elevenpatients were males and the remaining four were females, which also highlighted a greater incidence of medial canthal tumors in the male gender. Conclusion:  Glabellar rotation flap is a suitable procedurefor themedial canthal area restoration after the tumor excision and can be customizedas per the characteristics of the surrounding skin as well as thesite, dimensions, and profundity of the defect. Key Words:  Medial canthal tumor, Glabellar rotation flap, Medial canthus.

The Digi-Table Method as a Tool for Reflecting on Research Ethics

2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 177-177
Author(s):  
Wim Van Der Molen ◽  
◽  
Els Maeckelberghe ◽  
◽  
◽  
...  
Keyword(s):  
Research Ethics ◽  
Ethical Review ◽  
Scientific Integrity ◽  
Societal Impact ◽  
Educational Tool ◽  
Human Beings ◽  
Review Committee ◽  
Learning Content ◽  
Ethical Review Committee

"concepts and processes by means of a digitable. It is a tool for familiarizing users with complicated and complex issues, learning content, and addressing the more methodical aspects didactically. In this project, we have adapted the DTM for reflecting on research ethics, i.c. research with human beings and its ethical requirements and the review by the medical ethical review committee (MREC). A MREC reviews research proposals based on various (ethical) requirements and requires researchers to understand the ethical consequences and societal impact of their research. Before writing their own proposals, it is important for students to know and understand these ethical requirements and the process through which research proposals are reviewed. In order to train this, we prepared the digitable to simulate the review of a research protocol by an MREC and adapted it into an existing assignment on research ethics for master students. The students were informed of our aim and the use of DTM as an educational tool, and asked for consent. We invited them to critically assess the activity and we ensured participation would not influence their grade. The students reported a better understanding of the medical ethical review and felt it would improve their own work. From the educator’s perspective, the quality of argumentation of the review was much improved compared to previous years. The DTM as an educational tool is now a standard element in different master courses on scientific integrity. "

scholarly journals A proportional study of contemporary Bio safety rules and Islamic traditions regarding innate privileges of animals

2020 ◽  
pp. 137-146
Author(s):  
Yasir Wattu ◽  
Yasir Farooq
Keyword(s):  
Animal Rights ◽  
Human Life ◽  
Fundamental Rights ◽  
Controversial Issue ◽  
Islamic Education ◽  
Ethical Review ◽  
Proper Treatment ◽  
Review Committee ◽  
Research Activities ◽  
Ethical Review Committee

Biosafety is the anticipation of significant forfeiture of biotic reliability, concentrating equally on bionetwork and hominid fitness. Use of animals and plants for experimental purposes is a controversial issue in recent days. Advanced states have constituted its biosafety and bioethical rules for security and survival of animals. Which prohibited unethical use of animals and ill treatment. All academic and research institutions are bound to constitute an ethical review committee which is assigned to review and supervise research activities conducted in institute. Contemporary Bioethical rules are assumed to secure the basic rights of animals. Islam has also set ethical principles for survival and security of animals and assure their innate privileges. Animals are an inordinate sanctification of Allah Almighty, many of our daily necessities are associated with them, and there is no denying the importance of animals in human life. As per Islamic education feeding and proper treatment and shelter are fundamental rights of animals and owner of animals is bound to provide these facilities. Moreover, cursing, beating, teasing and unnecessarily slaughter of animals is disliked. Major difference between contemporary bioethical rules regarding animal rights and Islamic teachings is use of animal for food purposes.

scholarly journals Myasthenia Gravis Exacerbation and Myasthenic Crisis Associated With COVID19: Case Series and Literature Review.

2021 ◽  
Author(s):  
Cleonisio Leite Rodrigues ◽  
Hermany Capistrano Freitas ◽  
Paulo Reges Oliveira Lima ◽  
Pedro Helder de Oliveira Junior ◽  
José Marcelino Aragão Fernandes ◽  
...  
Keyword(s):  
Literature Review ◽  
Neuromuscular Junction ◽  
Hospital Mortality ◽  
Myasthenia Gravis ◽  
Viral Infections ◽  
Case Series ◽  
Previous Treatment ◽  
Autoimmune Disorder ◽  
Myasthenic Crisis

Abstract Myasthenia Gravis (MG) is an autoimmune disorder of the neuromuscular junction that can be exacerbated by many viral infections, including COVID19. Management of MG exacerbations is challenging in this scenario. We report 8 cases of MG exacerbation or myasthenic crisis associated with COVID19 and discuss prognosis and treatment based on a literature review. Most patients were female (7/8), with an average age of 47.1 years. Treatment was immunoglobulin (IVIG) in 3 patients, plasma exchange (PLEX) in 2 patients, and adjustment of baseline drugs in 3. In-hospital mortality was 25% and 37.5% in 2-month follow-up. This is the largest case series of MG exacerbation or myasthenic crisis due to COVID19 to this date. Mortality was considerably higher than in myasthenic crisis of other etiologies. Previous treatment for MG or acute exacerbation treatment did not seem to interfere with prognosis, although sample size was too small to draw definitive conclusions. Further studies are needed to understand the safety and effectiveness of interventions in this setting, particularly of PLEX, IVIG, rituximab and tocilizumab.

MAPPING AFRICAN ETHICAL REVIEW COMMITTEE ACTIVITY ONTO CAPACITY NEEDS: THE MARC INITIATIVE AND HRWEB'S INTERACTIVE DATABASE OF RECS IN AFRICA

2012 ◽  
Vol 12 (2) ◽  
pp. 74-86 ◽  
Author(s):  
CAREL IJSSELMUIDEN ◽  
DEBBIE MARAIS ◽  
DOUGLAS WASSENAAR ◽  
BOITUMELO MOKGATLA-MOIPOLAI
Keyword(s):  
Ethical Review ◽  
Review Committee ◽  
Ethical Review Committee
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