Qtc Interval Dispersion in Patients with Acute Str

Introduction: Dengue virus infection (DENV) is an arboviral disease that affects millions of people in many countries throughout the world every year. The disease is caused by the bite of a mosquito (Aedes aegypti and / or Aedes albopictus). The symptoms/signs observed in this arboviral disease are unspecific, and the blood count usually shows leukopenia and thrombocytopenia. Although ECG changes may be observed in DENV, little is known about parameters of ventricular repolarization in patients with this condition. Accordingly, the aim of this study was to evaluate the QTc and QT interval dispersion to detect ventricular repolarization changes in patients with DENV. Methodology: Ninety-three consecutive patients seen during DENV epidemics in a small town with non-complicated DENV were included; 93 normal individuals served as controls. Clinical data, blood count and the 12-lead ECG were obtained from each individual. Results: The QTc duration was higher in patients with DENV in comparison to controls. Furthermore, 5% of DENV patients had abnormal lengthening of the QTc interval. No difference regarding QT interval dispersion was observed between DENV patients and controls. No DENV patient had increased lengthening of the QT interval dispersion. Conclusions: Myocardial repolarization changes do occur in patients with DENV. Having into account the potential impact of these changes on patients’ outcome, and because 12-lead ECG is not routinely recommended in the setting of DENV in our country, we recommend that a 12-lead ECG be taken from each patient with this condition during DENV epidemics.

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GW26-e2326 The effect of serum N-terminal pro-brain natriuretic peptide(NT-proBNP) and QTc interval dispersion in the diagnosis of CHF and evaluation of heart function

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2015.06.803 ◽

2015 ◽

Vol 66 (16) ◽

pp. C210

Author(s):

Ruihua Wang ◽

Yanfen Li ◽

Yuhong Huang ◽

Lanjun Sun

Keyword(s):

Brain Natriuretic Peptide ◽

Natriuretic Peptide ◽

Heart Function ◽

Qtc Interval ◽

Interval Dispersion

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Assessment of QTc interval dispersion in patients with chronic heart failure secondary to Chagas–Hypertensive cardiomyopathy

International Journal of Cardiology ◽

10.1016/j.ijcard.2006.08.037 ◽

2007 ◽

Vol 121 (1) ◽

pp. 93-94 ◽

Cited By ~ 1

Author(s):

Martina B. Pinheiro ◽

Reinaldo B. Bestetti ◽

José A. Cordeiro

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Qtc Interval ◽

Interval Dispersion

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Reduction of QTc interval dispersion. Potential mechanism of cardiac protection of pyridostigmine bromide

Arquivos Brasileiros de Cardiologia ◽

10.1590/s0066-782x2000000900002 ◽

2000 ◽

Vol 75 (3) ◽

pp. 210-213 ◽

Cited By ~ 9

Author(s):

Renata Rodrigues Teixeira de Castro ◽

Salvador Manoel Serra ◽

Antonio Claudio Lucas da Nóbrega

Keyword(s):

Pyridostigmine Bromide ◽

Qtc Interval ◽

Potential Mechanism ◽

Cardiac Protection ◽

Interval Dispersion

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Prognostic value of QTc interval dispersion changes during exercise testing in hypertensive men

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh0802016d ◽

2008 ◽

Vol 136 (1-2) ◽

pp. 16-21 ◽

Cited By ~ 2

Author(s):

Dragan Djordjevic ◽

Branko Lovic ◽

Marina Deljanin-Ilic ◽

Stevan Ilic ◽

Ivan Tasic ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Exercise Testing ◽

Cardiovascular Events ◽

Ventricular Hypertrophy ◽

Prognostic Significance ◽

Left Ventricular ◽

Qtc Interval ◽

Qtc Dispersion ◽

Interval Dispersion

INTRODUCTION The prognostic significance of QTc dispersion changes during exercise testing (ET) in patients with left ventricular hypertrophy is not clear. OBJECTIVE The aim was to study the dynamics of QTc interval dispersion (QTcd) in patients (pts) with left ventricular hypertrophy (LVH) during the exercise testing and its prognostic significance. METHOD In the study we included 55 men (aged 53 years) with hypertensive left ventricular hypertrophy and a negative ET (LVH group), 20 men (aged 58 years) with a positive ET and 20 healthy men (aged 55 years). There was no statistically significant difference in the left ventricular mass index (LVMI) between LVH group and ILVH group (160.9?14.9 g/m2 and 152.8?22.7 g/m2). The first ECG was done before the ET and the second one was done during the first minute of recovery, with calculation of QTc dispersion. The patients were followed during five years for new cardiovascular events. RESULTS During the ET, the QTcd significantly increased in LVH group (56.8?18.0 - 76.7?22.6 ms; p<0.001). A statistically significant correlation was found between the amount of ST segment depression at the end of ET and QTc dispersion at the beginning and at the end of ET (r=0.673 and r=0.698; p<0.01). The QTc dispersion was increased in 35 (63.6%) patients and decreased in 20 (36.4%) patients during the ET. Three patients (5.4%) in the first group had adverse cardiovascular events during the five-year follow-up. A multiple stepwise regression model was formed by including age, LVMI, QTc interval, QTc dispersion and change of QTc dispersion during the ET. There was no prognostic significance of QTc interval and QTc dispersion during five-year follow-up in regard to adverse cardiovascular events, but prognostic value was found for LVMI (coefficient ?=0.480; p<0.001). CONCLUSION The increase of QTc interval dispersion is common in men with positive ET for myocardial ischemia and there is a correlation between QTc dispersion and amount of ST segment depression. The increase of QTc interval dispersion during negative ET in patients with left ventricular hypertrophy has no significant predictive value for adverse cardiovascular events, as shown in our five-year follow-up study, but it requires confirmation by investigation of larger groups of patients.

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Prolonged P-Wave and QT Dispersion in Children with Inflammatory Bowel Disease in Remission

BioMed Research International ◽

10.1155/2017/6960810 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Helen Aghdasi Bornaun ◽

Nuh Yılmaz ◽

Günsel Kutluk ◽

Reyhan Dedeoğlu ◽

Kazım Öztarhan ◽

...

Keyword(s):

Holter Monitoring ◽

Qt Dispersion ◽

Wave Dispersion ◽

P Wave ◽

Qtc Interval ◽

Dispersion Parameters ◽

P Wave Dispersion ◽

Mean Values ◽

Inflammatory Bowel ◽

Interval Dispersion

Objectives.Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory bowel diseases (IBD) with unclear underlying aetiologies. Severe cardiac arrhythmias have been emphasised in a few studies on adult IBD patients. This study aimed to investigate the alteration of the P-wave and QT interval dispersion parameters to assess the risk of atrial conduction and ventricular repolarisation abnormalities in pediatric IBD patients.Patients and Methods.Thirty-six IBD patients in remission (UC: 20, CD: 16) aged 3–18 years and 36 age- and sex-matched control patients were enrolled in the study. Twelve-lead electrocardiograms were used to determine durations of P-wave, QT, and corrected QT (QTc) interval dispersion. Transthoracic echocardiograms and 24-hour rhythm Holter recordings were obtained for both groups.Results.The P-wave dispersion, QT dispersion, and QTc interval dispersion (Pdisp, QTdisp, and QTcdisp) were significantly longer in the patient group. The mean values of Pminimum, Pmaximum, and QTcminimum were significantly different between the two groups. The echocardiography and Holter monitoring results were not significantly different between the groups. Furthermore, no differences in these parameters were detected between the CD and UC groups.Conclusion.Results suggest that paediatric IBD patients may carry potential risks for serious atrial and ventricular arrhythmias over time even during remission.

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