scholarly journals Influence of Acetaldehyde on Oral Epithelial Cells

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Miyazaki Yuji ◽  
Okuyama Ayako ◽  
Hoshino Miyako ◽  
Nishimura Michiko ◽  
Kikuchi Kentaro
Keyword(s):  
Epithelial Cells ◽  
Oral Epithelial Cells ◽  
Oral Epithelial

Assessment of the Effect of Complete Denture Adhesives on Oral Epithelial Cells’ DNA in Elderly Patients with Controlled Diabetes

2018 ◽  
Vol 64 (3) ◽  
pp. 2747-2756
Author(s):  
Noha El-Shaheed ◽  
Amira Gomaa ◽  
Ashraf Zakaria
Keyword(s):  
Epithelial Cells ◽  
Elderly Patients ◽  
Complete Denture ◽  
Oral Epithelial Cells ◽  
Denture Adhesives ◽  
Oral Epithelial

scholarly journals Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis

2015 ◽  
Vol 83 (7) ◽  
pp. 2614-2626 ◽  
Author(s):  
Rohitashw Kumar ◽  
Darpan Saraswat ◽  
Swetha Tati ◽  
Mira Edgerton
Keyword(s):  
Candida Albicans ◽  
Epithelial Cells ◽  
Oral Candidiasis ◽  
Oral Microbiome ◽  
Proteinase Activity ◽  
Adhesion Properties ◽  
Content Type ◽  
Oral Epithelial Cells ◽  
Oral Epithelial ◽  
Cell Cell

Candida albicans, a commensal fungus of the oral microbiome, causes oral candidiasis in humans with localized or systemic immune deficiencies. Secreted aspartic proteinases (Saps) are a family of 10 related proteases and are virulence factors due to their proteolytic activity, as well as their roles in adherence and colonization of host tissues. We found that mice infected sublingually withC. albicanscells overexpressing Sap6 (SAP6OE and a Δsap8strain) had thicker fungal plaques and more severe oral infection, while infection with the Δsap6strain was attenuated. These hypervirulent strains had highly aggregative colony structurein vitroand higher secreted proteinase activity; however, the levels of proteinase activity ofC. albicansSaps did not uniformly match their abilities to damage cultured oral epithelial cells (SCC-15 cells). Hyphal induction in cells overexpressing Sap6 (SAP6OE and Δsap8cells) resulted in formation of large cell-cell aggregates. These aggregates could be produced in germinated wild-type cells by addition of native or heat-inactivated Sap6. Sap6 bound only to germinated cells and increasedC. albicansadhesion to oral epithelial cells. The adhesion properties of Sap6 were lost upon deletion of its integrin-binding motif (RGD) and could be inhibited by addition of RGD peptide or anti-integrin antibodies. Thus, Sap6 (but not Sap5) has an alternative novel function in cell-cell aggregation, independent of its proteinase activity, to promote infection and virulence in oral candidiasis.

scholarly journals Exogenous LL-37 but not homogenates of desquamated oral epithelial cells shows activity against Streptococcus mutans

2021 ◽  
pp. 1-7
Author(s):  
Alexandra Aidoukovitch ◽  
Elisabeth Bankell ◽  
Julia R. Davies ◽  
Bengt-Olof Nilsson
Keyword(s):  
Epithelial Cells ◽  
Streptococcus Mutans ◽  
Oral Epithelial Cells ◽  
Oral Epithelial

Cytoprotective effects of opioids on irradiated oral epithelial cells

2013 ◽  
Vol 21 (6) ◽  
pp. 883-889 ◽  
Author(s):  
Nada Charbaji ◽  
Peter Rosenthal ◽  
Monika Schäfer-Korting ◽  
Sarah Küchler
Keyword(s):  
Epithelial Cells ◽  
Oral Epithelial Cells ◽  
Oral Epithelial

scholarly journals Activation of Human Oral Epithelial Cells by Neutrophil Proteinase 3 Through Protease-Activated Receptor-2

2002 ◽  
Vol 169 (8) ◽  
pp. 4594-4603 ◽  
Author(s):  
Akiko Uehara ◽  
Shunji Sugawara ◽  
Koji Muramoto ◽  
Haruhiko Takada
Keyword(s):  
Epithelial Cells ◽  
Proteinase 3 ◽  
Oral Epithelial Cells ◽  
Protease Activated Receptor 2 ◽  
Oral Epithelial

scholarly journals Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and β-Defensin Secretion in Oral Epithelial Cells

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143158 ◽  
Author(s):  
Telma Blanca Lombardo Bedran ◽  
Marie-Pierre Morin ◽  
Denise Palomari Spolidorio ◽  
Daniel Grenier
Keyword(s):  
Epithelial Cells ◽  
Black Tea ◽  
Interleukin 8 ◽  
Oral Epithelial Cells ◽  
Black Tea Extract ◽  
Tea Extract ◽  
Oral Epithelial
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