scholarly journals Devices used for Treatment of Epilepsy

2020 ◽  
Vol 2 (02) ◽  
pp. 56-60
Author(s):  
Md. Niyaz Alam ◽  
Jainendra Jain ◽  
Azhar Danish Khan ◽  
Rahul Kaushik ◽  
Najam Ali Khan ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Epileptic Seizure ◽  
Vagus Nerve Stimulation ◽  
World Health ◽  
The World ◽  
Current Scenario ◽  
Drug Resistant Epilepsy ◽  
Health Organization ◽  
Spontaneous Recurrent Seizures

Epilepsy is a group of chronic neurological disorder of the brain that affects around 1-2% of the population across the world. According to the World Health Organization (WHO), epilepsy is characterized by periodically spontaneous seizures, which are usually due to excessive electrical discharges in a group of brain cells. The earlier day electroencephalogram (EEG) signals are useful tool for detection of epileptic seizures.Epileptogenesis is a slow process. After several months of initial insult, spontaneous recurrent seizures begin to appear. Epilepsy is considered to be resolved for individuals who are seizure-free for the last 10 years, with no seizure medicines for the last 5 years. Currently, used drugs available for treating epilepsy have draw backs like Epileptogenesis and other dose-related side effects. In spite of daily treatment, nearly 30% of patients continue to have convulsions and fail to provide a complete cure. Hence, there is a need for another alternative option to control the epileptic seizure and minimize the duration of seizure without taking a medicine and improving the quality of patient’s life. In current scenario the Vagus nerve stimulation (VNS) has become an important tool for controlling the epileptic seizure. Vagus nerve stimulation is used for patient with refractory and drug resistant epilepsy. Various non-drug therapies form preclinical to clinical for controlling seizures in epileptic patients with drug resistance current available have been highlighted in this review.

Vagus nerve stimulation for drug-resistant epilepsy

2019 ◽  
Vol 20 (3) ◽  
pp. 189-198 ◽  
Author(s):  
Laura Pérez-Carbonell ◽  
Howard Faulkner ◽  
Sean Higgins ◽  
Michalis Koutroumanidis ◽  
Guy Leschziner
Keyword(s):  
Vagus Nerve ◽  
Seizure Frequency ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Therapeutic Option ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy ◽  
Randomised Controlled

Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy. In randomised controlled trials, VNS implantation has resulted in over 50% reduction in seizure frequency in 26%–40% of patients within 1 year. Long-term uncontrolled studies suggest better responses to VNS over time; however, the assessment of other potential predictive factors has led to contradictory results. Although initially designed for managing focal seizures, its use has been extended to other forms of drug-resistant epilepsy. In this review, we discuss the evidence supporting the use of VNS, its impact on seizure frequency and quality of life, and common adverse effects of this therapy. We also include practical guidance for the approach to and the management of patients with VNS in situ.

scholarly journals VIOLÊNCIA CONTRA A MULHER: FACILIDADES E DIFICULDADES RELACIONADAS A ASSISTÊNCIA MULTIPROFISSIONAL

2018 ◽  
Vol 8 (1) ◽  
pp. 54
Author(s):  
Ana Paula Reis de Oliveira ◽  
Chalana Duarte Sena ◽  
Gilvânia Patrícia Do Nascimento Paixão ◽  
Josinete Gonçalves dos Santos Lírio
Keyword(s):  
Domestic Violence ◽  
Violence Against Women ◽  
Public Health Problem ◽  
World Health ◽  
Brazilian Literature ◽  
The World ◽  
Current Scenario ◽  
Violencia Domestica ◽  
Health Organization ◽  
Target Agent

Considerada pela Organização Mundial de Saúde (OMS) como problema de saúde pública, a violência contra a mulher (VCM) é uma epidemia mundial, estima-se que as mulheres em vivência de violência doméstica, ao longo de suas vidas, apresentam mais problemas de saúde e buscam, com mais frequência os serviços de saúde do que pessoas que não sofrem estes maus tratos. Diante do exposto, o presente estudo tem como objetivo: Identificar os fatores que facilitam e dificultam a assistência a saúde a mulher em situação de violência domestica segundo a literatura brasileira, visando à importância da identificação das mulheres em vivência de violência e a ampliação deste cuidado não apenas para a cura/tratamento, mas para o vínculo e acolhimento eficaz e humano entre o agente cuidador e o agente alvo de cuidados, visando à superação tanto do cenário atual, quanto de tal momento doloroso na vida na mulher.Descritores: Violência Doméstica e Sexual Contra a Mulher; Cuidados; associados ao uso do recurso booleano “AND”. ABSTRACT Considered by the World Health Organization (WHO) as a public health problem, violence against women (VCM) is a worldwide epidemic, it is estimated that women experiencing domestic violence throughout their lives have and seek health services more often than people who do not suffer from these ill-treatment. In view of the above, the present study aims to: Identify the factors that facilitate and hinder the health care of women in situations of domestic violence according to the Brazilian literature, aiming at the importance of identifying women in the experience of violence and the expansion of this care not only for the cure/treatment, but for the effective and humane bonding and reception between the caregiver agent and the target agent of care, aiming at overcoming both the current scenario and that painful moment in life in the woman. Descriptors: Domestic and Sexual Violence Against Women; Care; associated with the use of the boolean "AND".

scholarly journals Vagus nerve stimulation for pediatric patients with drug-resistant epilepsy caused by genetic mutations: Two cases

2020 ◽  
Vol 8 (3) ◽  
pp. 138-148
Author(s):  
Xiaoya Qin
Keyword(s):  
Vagus Nerve ◽  
Empirical Evidence ◽  
Therapeutic Effect ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Pediatric Patients ◽  
Genetic Mutations ◽  
Drug Resistant ◽  
Therapeutic Impact ◽  
Drug Resistant Epilepsy

Vagus nerve stimulation (VNS) is a neuromodulation therapy increasingly used for treating drug-resistant epilepsy. However, it remains to be determined which patients are best suited for the treatment, and it is difficult to predict the therapeutic effect before the implantation. Mutations in some genes could lead to epilepsy. Here we report two cases of pediatric patients with drug-resistant epilepsy treated by VNS therapy: Patient 1 with ARX mutation achieved good outcomes; Patient 2 with the CDKL5 mutation did not show improvement. Additionally, the therapeutic impact of VNS on brain networks was investigated, hoping to provide some empirical evidence for a better understanding of the mechanism of VNS treatment.

scholarly journals Sign and magnitude scaling properties of heart rate fluctuations following vagus nerve stimulation in a patient with drug-resistant epilepsy

2018 ◽  
Vol 10 ◽  
pp. 78-81 ◽  
Author(s):  
Eduardo Gutiérrez-Maldonado ◽  
Claudia Ivette Ledesma-Ramírez ◽  
Adriana Cristina Pliego-Carrillo ◽  
José Javier Reyes-Lagos
Keyword(s):  
Heart Rate ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Drug Resistant ◽  
Scaling Properties ◽  
Magnitude Scaling ◽  
Heart Rate Fluctuations ◽  
Drug Resistant Epilepsy
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