scholarly journals MARIE FRANÇOIS XAVIER BICHAT (1771-1802)

2021 ◽  
Vol 10 (4) ◽  
pp. 58-63
Author(s):  
T. A. Fominykh ◽  
A. P. D’yachenko ◽  
V. S. Ulanov
Keyword(s):  
Modern Science ◽  
Critical Importance ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Practical Medicine ◽  
Transverse Fissure ◽  
Medical Disciplines ◽  
The Brain ◽  
French Surgeon ◽  
Tunica Intima

The article tells about the great French surgeon, anatomist and physiologist Marie-François Xavier Bichat, the founder of science about tissues – histology, discoverer in an anatomy and creator of such medical disciplines, as a thanatology (science about death) and pathoanatomy. The most essential moments and facts from biography of scientist are described, his basic scientific insights are briefly expounded. Main scientific works and publications, and also described by Bichat anatomic structures and formations are enumerated. His name is carried on by several eponyms in anatomy fossa (pterygopalatine fossa), Bichat’s protuberance (buccal fat pad), Bichat’s foramen (cistern of the vena magna of Galen), Bichat’s ligament (lower fasciculus of the posterior sacroiliac ligament), Bichat’s fissure (transverse fissure of the brain) and Bichat’s tunic (tunica intima vasorum). The substantive provisions of the scientific conceptions offered to them in morphology and pathoanatomy are expounded. The critical importance of scientific works and discoveries of Marie-François Xavier Bichat for modern science and practical medicine is emphasized

Endoscopically Harvested Buccal Fat Pad Flap: A Review of Seven Cases

2019 ◽  
Author(s):  
Somasundaram Subramaniam ◽  
Ricardo Carrau
Keyword(s):  
Fat Pad ◽  
Buccal Fat Pad

Fact file 1: Critical care and emergency medicine

2017 ◽  
Author(s):  
Daisy Fancourt
Keyword(s):  
Emergency Medicine ◽  
Critical Care ◽  
Sports Medicine ◽  
Orthopaedic Surgery ◽  
Extreme Environment ◽  
Disaster Medicine ◽  
Medical Attention ◽  
Life Threatening ◽  
Medical Disciplines ◽  
The Brain

Emergency medicine involves the care of patients who require immediate medical attention. The specialty encompasses a broad range of medical disciplines, including anaesthesia, cardiology (a field related to the heart), neurology (a field related to the brain), plastic surgery, orthopaedic surgery (surgery relating to the bones or muscles), and cardiothoracic surgery (surgery relating to the heart, chest, or lungs). There are also a number of subspecialties including extreme environment medicine, disaster medicine and sports medicine. Related to emergency medicine is the specialty of critical care medicine, which is concerned with the care of patients with life-threatening conditions often treated in intensive care settings....

scholarly journals Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D2-Serotonin 5-HT1A Heteromers

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1000
Author(s):  
Sylwia Łukasiewicz
Keyword(s):  
Physicochemical Parameters ◽  
Modern Science ◽  
Dopamine D2 ◽  
Targeted Transport ◽  
First Choice ◽  
New Strategy ◽  
Cell Components ◽  
Second Generation Antipsychotic ◽  
The Brain ◽  
Polymeric Nanocarrier

Clozapine, the second generation antipsychotic drug, is one of the prominent compounds used for treatment of schizophrenia. Unfortunately, use of this drug is still limited due to serious side effects connected to its unspecific and non-selective action. Nevertheless, clozapine still remains the first-choice drug for the situation of drug-resistance schizophrenia. Development of the new strategy of clozapine delivery into well-defined parts of the brain has been a great challenge for modern science. In the present paper we focus on the presentation of a new nanocarrier for clozapine and its use for targeted transport, enabling its interaction with the dopamine D2 and serotonin 5-HT1A heteromers (D2-5-HT1A) in the brain tissue. Clozapine polymeric nanocapsules (CLO-NCs) were prepared using anionic surfactant AOT (sodium docusate) as an emulsifier, and bio-compatible polyelectrolytes such as: poly-L-glutamic acid (PGA) and poly-L-lysine (PLL). Outer layer of the carrier was grafted by polyethylene glycol (PEG). Several variants of nanocarriers containing the antipsychotic varying in physicochemical parameters were tested. This kind of approach may enable the availability and safety of the drug, improve the selectivity of its action, and finally increase effectiveness of schizophrenia therapy. Moreover, the purpose of the manuscript is to cover a wide scope of the issues, which should be considered while designing a novel means for drug delivery. It is important to determine the interactions of a new nanocarrier with many cell components on various cellular levels in order to be sure that the new nanocarrier will be safe and won’t cause undesired effects for a patient.

scholarly journals Versatility of the pedicled buccal fat pad flap for the management of oroantral fistula: a retrospective study of 25 cases

2019 ◽  
Vol 41 (1) ◽  
Author(s):  
Jinyoung Park ◽  
Byung-do Chun ◽  
Uk-Kyu Kim ◽  
Na-Rae Choi ◽  
Hong-Seok Choi ◽  
...  
Keyword(s):  
Bone Graft ◽  
Graft Failure ◽  
Fistula Closure ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Dental Surgery ◽  
Female Ratio ◽  
Maxillary Bone ◽  
Oroantral Fistula

Abstract Purpose Maxillary bone grafts and implantations have increased over recent years despite a lack of maxillary bone quality and quantity. The number of patients referred for oroantral fistula (OAF) due to implant or bone graft failure has increased, and in patients with an oroantral fistula, the pedicled buccal fat pad is viewed as a robust, reliable option. This study was conducted to document the usefulness of buccal fat pad grafts for oroantral fistula closure. Materials and methods We retrospectively studied 25 patients with OAF treated with a buccal fat pad graft from 2015 to 2018. Sex, age, OAF location, cause, duration, presence of systemic disease, smoking, previous dental surgery, and side effects were investigated. Results A total of 25 patients were studied. Mean patient age was 54.8 years, and the male to female ratio was 19:6. Causes of oroantral fistula were cyst enucleation, tumor resection, implant removal, bone graft failure, and extraction. Excellent results were obtained in 23 (92%) of the 25 patients. In the other two patients that both smoked, a small fistula was observed during follow-up. No recurrence of oroantral fistula was observed after 2 months to 1 year of follow-up. Conclusions The incidence of oroantral fistula is increasing due to implant and bone graft failures. Oroantral fistula closure using a pedicled buccal fat pad was found to have a high success rate.

Effects of in vitro low oxygen tension preconditioning of buccal fat pad stem cells on in Vivo articular cartilage tissue repair

Life Sciences ◽  
2021 ◽  
pp. 119728
Author(s):  
Fatemeh Dehghani Nazhvani ◽  
Leila Mohammadi Amirabad ◽  
Arezo Azari ◽  
Hamid Namazi ◽  
Simzar Hosseinzadeh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Articular Cartilage ◽  
Tissue Repair ◽  
Cartilage Tissue ◽  
Low Oxygen ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Low Oxygen Tension

Aging Process of Lateral Facial Fat Compartments: A Retrospective Study

2021 ◽  
Author(s):  
Ching-Sheng Yang ◽  
Yau-Li Huang ◽  
Chun-Bing Chen ◽  
Chih-Ying Deng ◽  
Yu-Ting Liu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Retrospective Study ◽  
Aging Process ◽  
Resonance Imaging ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Time Points ◽  
Axial View ◽  
Labiomandibular Fold

Abstract Background Since 2007, when the anatomy of facial fat compartment was described, an increasing number of studies on the aging process of the compartment of cadavers has emerged. Objectives The authors evaluated the aging changes of lateral facial fat compartments on the same person. Methods Sixty-three patients were included in this retrospective study. All patients had magnetic resonance imaging scans with at least 4 years apart. The authors targeted the fat compartments of the superficial temporal, subcutaneous temporal, and buccal fat pad, comparing the data on different time points. Results The thickness of the subcutaneous temporal fat did not change significantly. The 3 diameters of the superficial temporal fat compartment all became thinner on the axial view (P < 0.05). On the sagittal view, the superficial temporal fat elongated from 38.89 mm to 43.74 mm (P < 0.05). The buccal fat compartment also lengthened from 68.73 mm to 74.39 mm (P < 0.05) and had a positive correlation with follow-up duration only. Conclusions The study revealed the fat compartment change on the same person with time. The temporal hollow mainly originates from the thinner part of the superficial temporal fat. The descending of the buccal fat pad aggravates the labiomandibular fold. By understanding the aging process more fully, we can rejuvenate our patients more naturally.

scholarly journals The use of a pedicled buccal fat pad for reconstruction of posterior mandibular defects

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Hyen Woo Lee ◽  
Sung ok Hong ◽  
Heeyeon Bae ◽  
Youngjin Shin ◽  
Yu-jin Jee
Keyword(s):  
Reliable Method ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Case Presentation ◽  
Oroantral Fistula ◽  
Treated Area ◽  
Radiologic Imaging ◽  
Long Time

Abstract Background The pedicled buccal fat pad has been used for a long time to reconstruct oral defects due to its ease of flap formation and few complications. Many cases related to reconstruction of defects in the maxilla, such as closing the oroantral fistula, have been reported, but cases related to the reconstruction of defects in the mandible are limited. Under adequate anterior traction, pedicled buccal fat pad can be a reliable and effective method for reconstruction of surgical defects in the posterior mandible. Case presentation This study describes two cases of reconstruction of surgical oral defects in the posterior mandible, all of which were covered by a pedicled buccal fat pad. The size of the flap was sufficient to perfectly close the defect without any tension. Photographic and radiologic imaging showed successful closure of the defects and no problems were noted in the treated area. Conclusion In conclusion, the pedicled buccal fat pad graft is a convenient and reliable method for the reconstruction of surgical defects on the posterior mandible.

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