scholarly journals Osteítis por radiación y fracturas por insuficiencia pélvica en paciente con adenocarcinoma de próstata tratado con radioterapia. Aspectos clínicos y radiográficos de la enfermedad.

2020 ◽  
pp. 91-98
Author(s):  
Rafael FERNÁNDEZ GABARDA ◽  
M BALLESTA MORATALLA ◽  
MJ SANGÜESA NEBOT
Keyword(s):  
Risk Factors ◽  
Radiation Therapy ◽  
Bone Cells ◽  
Insufficiency Fracture ◽  
Prostate Adenocarcinoma ◽  
Nerve Tissue ◽  
Pelvic Radiation ◽  
Diagnostic Aspects ◽  
Radiation Induced ◽  
Pelvic Insufficiency Fracture

Radiation osteitis is an anatomopathological term first coined by Ewing in 1926, refers to a radiation-induced inflammatory response in blood vessels, nerve tissue, and bone cells that can lead to fractures of the trabecular and cortical bone. Pelvic insufficiency fracture is a stress fracture over a weakened bone, seen in patients who have certain risk factors such as osteoporosis, connective tissue disease, use of corticosteroids, and especially in patients who have been treated with pelvic radiation therapy for rectal, anal, urogenital, and prostate tumors. We present the case of a 73-year-old patient with fractures due to pelvic failure treated four years before prostate adenocarcinoma with radiotherapy and hormone therapy. Clinical and radiographic diagnostic aspects are discussed.

scholarly journals Radiation induced vesicovaginal fistula

2018 ◽  
Vol 13 (2) ◽  
Author(s):  
Kenusha Devi Tiwari
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Radiation Therapy ◽  
Radical Hysterectomy ◽  
Vesicovaginal Fistula ◽  
Fistula Repair ◽  
Pelvic Radiation ◽  
Radiation Induced

Case: A 63 years old female visited our outpatient department for involuntary loss of urine per vagina since 1.5 year. She had undergone radical hysterectomy and radiotherapy 16 years ago for cervical carcinoma. With positive dye test, on examination she had vesicovaginal fistula with Goh classification of 2biii. She underwent fistula repair via vaginal approach. After 3 weeks of catheterization, successful closure was achieved. Radiation therapy is an effective treatment for cervical cancer. However, of various complications, irradiation sometimes cause the formation of fistula between vagina and bladder and or rectum compromising the quality of life. Pelvic radiation is the primary cause of delayed vesicovaginal fistula with incidence of 13%. Majority of them become apparent 1.5-2 year after termination of radiotherapy and can occur even up-to 20-30 years after the original insult. Keywords: cervical cancer, fistula, radiation induced

scholarly journals Frequency of Certain Established Risk Factors in Soft Tissue Sarcomas in Adults: A Prospective Descriptive Study of 658 Cases

Sarcoma ◽  
2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
Nicolas Penel ◽  
Jessica Grosjean ◽  
Yves Marie Robin ◽  
Luc Vanseymortier ◽  
Stéphanie Clisant ◽  
...  
Keyword(s):  
Risk Factors ◽  
Radiation Therapy ◽  
Soft Tissue ◽  
Genetic Disease ◽  
Soft Tissue Sarcomas ◽  
Descriptive Study ◽  
Genetic Syndromes ◽  
Genetic Syndrome ◽  
Rare Tumours ◽  
Radiation Induced

Soft tissue sarcomas are rare tumours with infrequent identified aetiological factors. Several genetic syndromes as well as previous radiation therapy and/or chronic lymphoedema have been suspected to predispose to some soft tissue sarcomas. Between January 1997 and September 2005, we carried out a prospective descriptive study to estimate the frequency of some particular etiological factors among 658 patients with soft tissue sarcomas. Sarcomas associated with a clinically identified genetic disease represent 2.8% out of all cases (95%CI: 1.5–3.8%). Most of these cases (14/19) are related to Recklinghausen neurofibromatosis. Radiation-induced sarcomas represent 3.3% out of all cases (95%CI: 1.7–5.1%). Most of these cases (9/22) are related to prior breast cancer treatment. We had observed only 1 case of Stewart-Treves syndrome. Liposarcoma, the most frequent histological subtype observed, is not associated with any particular aetiological entity. Finally, most of the adult soft tissue sarcomas are not related to any classical clinically identified genetic disease or previous radiation therapy and/or chronic lymphoedema risk factors. Frequency of underlying genetic syndrome which may predispose to soft tissue sarcomas could be higher than previously reported.

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