scholarly journals Influence of Packaging and Stability Test Assessment of an Anti-aging Cosmetic Cream

2018 ◽  
Vol 55 (3) ◽  
pp. 426-430
Author(s):  
Anca Maria Juncan ◽  
Luca Liviu Rus
Keyword(s):  
Quality Control ◽  
Stability Test ◽  
Stability Studies ◽  
Stability Tests ◽  
Cosmetic Product ◽  
Accelerated Stability ◽  
Test Assessment ◽  
Cosmetic Formulation ◽  
Plastic Containers

The aim of this study was the development and formulating of a cosmetic product and the assessment of compatibility tests performed on the product, transfered to the cosmetic jar. Sample of cosmetic cream were stored using 50 mL PP (Polypropylene) plastic containers. The developed cosmetic formulation was monitored under accelerated stability studies. Accelerated stability tests were performed over a period of 30 days while maintaining the product at 4, 20 and 40�C. Quality control initial, and after initiating the accelerated stability test was performed for the developed cosmetic formulation.

scholarly journals Primary Packaging and Stability Evaluation of a Serum Used for the Periorbital Area of the Sensitive Eye

2019 ◽  
Vol 56 (2) ◽  
pp. 360-365
Author(s):  
Andrei Catalin Muntean ◽  
Anca Maria Juncan ◽  
Dana Georgiana Moisa ◽  
Andreea Loredana Vonica ◽  
Luca Liviu Rus ◽  
...  
Keyword(s):  
Quality Control ◽  
Hyaluronic Acid ◽  
Stability Test ◽  
Stability Evaluation ◽  
Stability Studies ◽  
Stability Tests ◽  
Cosmetic Product ◽  
Accelerated Stability ◽  
Cosmetic Formulation ◽  
Glass Bottles

The aim of this study was the development and formulating of an eye contour serum containing hyaluronic acid (HA) and the assessment of stability tests performed for the cosmetic product, transfered into a glass cosmetic bottle with polipropylene (PP) pump and cap. Sample of cosmetic serum were stored using 20 mL glass bottles with PP (Polypropylene) pump and cap. The developed cosmetic formulation was monitored under accelerated stability studies, performed over a period of 30 days while maintaining the product at 4, 20 and 40�C. Quality control initial, and after initiating the accelerated stability test was performed for the developed cosmetic formulation.

scholarly journals Packaging Evaluation and Safety Assessment of a Cosmetic Product

2018 ◽  
Vol 55 (4) ◽  
pp. 644-647
Author(s):  
Anca Maria Juncan
Keyword(s):  
Quality Control ◽  
Safety Assessment ◽  
Stability Test ◽  
Stability Studies ◽  
Cosmetic Product ◽  
Accelerated Stability ◽  
Cosmetic Formulation

The aim of this study was the development and formulating of a cosmetic product for bodycare and the assessment of compatibility tests performed on the product, transfered into a poliethylene (PE) cosmetic bottle. Sample of cosmetic cream were stored using 200 ml PE plastic bottles with PP (Polypropylene) cap. The developed cosmetic formulation was monitored under accelerated stability studies, performed over a period of 30 days while maintaining the product at 4, 20 and 40�C. Quality control initial, and after initiating the accelerated stability test was performed for the developed cosmetic formulation.

scholarly journals Application of Accelerated Stability Studies on Linagliptin by HPTLC

2017 ◽  
Vol 29 (1) ◽  
pp. 94-98 ◽  
Author(s):  
Santosh R. Butle ◽  
Padmanabh B. Deshpande
Keyword(s):  
Stability Studies ◽  
Accelerated Stability

Optimization of Performance Variables of Exemestane Nanosuspension Using Box-Behnken Design to Improve Dissolution and Oral Bioavailability

2021 ◽  
Vol 18 ◽  
Author(s):  
Komal Parmar ◽  
Jay Shah
Keyword(s):  
Oral Bioavailability ◽  
In Vitro Dissolution ◽  
Pharmacokinetic Parameters ◽  
Average Particle ◽  
Stability Studies ◽  
Box Behnken Design ◽  
Media Milling ◽  
Dissolution Properties ◽  
Accelerated Stability

Purpose: Present investigation was aimed to fabricate nanocrystal of exemestane, an anticancer drug with poor dissolution properties and oral bioavailability. Methods: Influence of various process parameters on the formulation of exemestane nanosuspension using media milling technique were investigated in the trial batches. Box-Behnken design was applied with independent variables identified in the preliminary studies, viz. X1-Milling time, X2-Amount of stabilizer and X3-Amount of milling agent. In vitro dissolution and in vivo studies were carried out. Solid state characterization (PXRD, SEM, and DSC) studies demonstrated physical changes in drug due to nano-crystallization. Accelerated stability studies of optimized formulation were carried out. Results: Individual process attributes exhibited significant effect on the average particle size of exemestane nanosuspension. Dissolution studies revealed enhancement in drug release rate as compared to pure exemestane powder. The in vivo pharmacokinetic parameters of exemestane nanosuspension showed significant improvement in Cmax and AUC0-t, about 283.85% and 271.63% respectively suggesting amelioration in oral bioavailability by 2.7-fold as compared to pure exemestane. Accelerated stability studies of the optimized formulation suggested stability of the nanocrystals for at least sixmonth period. Conclusion: Nanocrystals prepared by media milling technique were successful in improving the poor dissolution properties and oral bioavailability of exemestane.

Kinetic Model Development for Accelerated Stability Studies

2016 ◽  
Vol 18 (4) ◽  
pp. 1158-1176 ◽  
Author(s):  
Don Clancy ◽  
Neil Hodnett ◽  
Rachel Orr ◽  
Martin Owen ◽  
John Peterson
Keyword(s):  
Kinetic Model ◽  
Model Development ◽  
Stability Studies ◽  
Accelerated Stability

scholarly journals ACCELERATED STABILITY STUDIES OF FLURBIPROFEN FILM COATED TABLETS OF FIVE DIFFERENT NATIONAL BRANDS IN PAKISTAN

2013 ◽  
Vol 3 (2) ◽  
Author(s):  
Ibrahim Javed ◽  
Saeed ur Rasheed Nazir ◽  
Nazar Muhammad Ranjha ◽  
Asif Massud ◽  
Liaqat Hussain
Keyword(s):  
Stability Studies ◽  
National Brands ◽  
Accelerated Stability

scholarly journals Assay method for quality control and stability studies of a new antimalarial agent (CDRI 99/411)

2013 ◽  
Vol 3 (5) ◽  
pp. 335-340 ◽  
Author(s):  
Kiran Khandelwal ◽  
Shakti Deep Pachauri ◽  
Sofia Zaidi ◽  
Pankaj Dwivedi ◽  
Ashok Kumar Sharma ◽  
...  
Keyword(s):  
Quality Control ◽  
Assay Method ◽  
Stability Studies ◽  
Antimalarial Agent

Fully-Automated Synthesis of 177Lu Labelled FAPI Derivatives On The Module Modular Lab-Eazy

2021 ◽  
Author(s):  
Kurtulus Eryilmaz ◽  
Benan KILBAS
Keyword(s):  
Quality Control ◽  
Chromatographic Analysis ◽  
Radiochemical Purity ◽  
Radiochemical Yield ◽  
Automated System ◽  
Automated Synthesis ◽  
Modular Approach ◽  
Stability Studies ◽  
European Pharmacopoeia ◽  
First Time

Abstract Backround: To the best of our knowledge, manually production of [177Lu]Lu-FAPI radiopharmaceutical derivatives has been only described in literature. In this work, a fully-automated [177Lu]Lu-FAPI synthesis has been well designed for the first time using commercially available synthesis module. In addition to the development of an automated system with disposable cassette, quality control (QC) and stability studies were comprehensively employed. Results A fully automated synthesis of [177Lu]Lu-FAPI derivatives was achieved on the Modular Lab Eazy (ML Eazy) with high radiochemical yield (85–90%). Chromatographic analysis indicated the formation of radiosynthesis with an absolute radiochemical purity (99%). Stability experiments clarified the durability of the products within 4 days. All obtained specifications are consistent to European Pharmacopoeia. Conclusion A fully automated synthesis of [177Lu]Lu-FAPI radiopharmaceuticals were accomplished regarding quality control standards and quality assurance by using commercially available a modular approach namely ML Eazy with disposable customized cassette and template.

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