Immuno-biological Assessments of Temporomandibular Joint Disease in Patients with Immune-mediated Rheumatic Conditions. A cross sectional study of 273 cases

Temporomandibular joint (TMJ) is commonly involved in various immune-mediated rheumatic disorders accounting for significant disability and impaired quality of life. The aim of our study was to assess inflammatory and immune parameters in patients with TMJ arthritis related to rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) and to identify potential relation with severity and dysfunction of TMJ pathology. We performed a cross-sectional study in a cohort of 433 consecutive RA, 32 JIA, 258 AS, and 103 PsA. Only patients presenting with clinically significant TMJ involvement (273) related to their rheumatic condition were included in the final analysis. TMJ involvement is traditionally described in chronic inflammatory rheumatic disorders, particularly in patients with higher levels of inflammation as detected in rheumatoid arthritis and psoriatic arthritis. Disease activity and severity, as well as biological and positive serological assessments (rheumatoid factor, anti-cyclic citrullinated peptide, IL-1) remain significant determinants of the severity of TMJ arthritis.

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Patient education, disease activity and physical function: can we be more targeted? A cross sectional study among people with rheumatoid arthritis, psoriatic arthritis and hand osteoarthritis

Arthritis Research & Therapy ◽

10.1186/ar4339 ◽

2013 ◽

Vol 15 (5) ◽

pp. R156 ◽

Cited By ~ 29

Author(s):

Răzvan G Drăgoi ◽

Mwidimi Ndosi ◽

Martina Sadlonova ◽

Jackie Hill ◽

Mona Duer ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Psoriatic Arthritis ◽

Patient Education ◽

Disease Activity ◽

Physical Function ◽

Cross Sectional Study ◽

Hand Osteoarthritis ◽

Sectional Study ◽

Cross Sectional

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Comparing the prevalence of metabolic syndrome in systemic lupus erythematosus, rheumatoid arthritis and psoriatic arthritis: A cross sectional study

Rheumatology Research ◽

10.22631/rr.2018.69997.1044 ◽

2018 ◽

Vol 3 (2) ◽

pp. 69-75

Author(s):

Maryam Mobini ◽

Fatemeh Niksolat ◽

Reza Ali Mohammadpour ◽

Sarah Sadr ◽

Saeed Dashti dargahloo

Keyword(s):

Rheumatoid Arthritis ◽

Systemic Lupus Erythematosus ◽

Metabolic Syndrome ◽

Psoriatic Arthritis ◽

Lupus Erythematosus ◽

Cross Sectional Study ◽

Sectional Study ◽

Systemic Lupus ◽

Cross Sectional

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Lung involvement prevalence in patients with early rheumatoid arthritis without known pulmonary disease: a multicentric cross sectional study

Advances in Rheumatology ◽

10.1186/s42358-021-00209-0 ◽

2021 ◽

Vol 61 (1) ◽

Author(s):

Francisco Paulin ◽

Anastasia Secco ◽

Federico Benavidez ◽

Juan José Rodríguez Moncalvo ◽

Orlando Gabriel Carballo ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Lung Disease ◽

Cross Sectional Study ◽

Joint Disease ◽

Joint Involvement ◽

Lung Involvement ◽

Functional Tests ◽

Sectional Study ◽

Cross Sectional ◽

Early Ra

Abstract Background Clinically evident interstitial lung disease (ILD) affects between 10 and 42% of the patients with rheumatoid arthritis (RA). Airway involvement seems to be even more common. Most of the available evidence comes from studies performed in established RA patients. The aim of our study was to know the prevalence of non-diagnosed lung disease (airway and interstitial involvement) in patients with early RA and look for associated factors. Methods We designed an observational, multicenter, cross-sectional study, and included patients with RA of less than two years since diagnosis. We performed a structured questionnaire, HRCT and lung functional tests looking for lung disease, together with joint disease evaluation. We analyzed which variables were associated with the presence of lung disease on HRCT. Results We included 83 patients, 83% females. The median (IQR) of time since RA diagnosis was 3 (1–6) months. In the HRCT, 57 patients had airway compromisea (72%), and 6 had interstitial abnormalities (7.5%). The most common altertion found in lung functional tests was a reduced DLCO (14%). The presence of at least one abnormality in the physical exam was associated with lung involvement on HRCT [13 (21.6%) vs 0 (0%); p = 0.026]. Also, patients with lung involvement presented significantly lower values of FVC% and DLCO%, and higher values of RV/TLC. No variable related to joint involvement was found associated with alterations in HRCT. Conclusion Our study shows that a large proportion of early RA patients has abnormal findings in HRCT. Further studies are required to confirm these findings.

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