Development of Single-step Protocols for the Separation of Naphtodianthrones from St. John�s Wort Extracts

2018 ◽  
Vol 69 (8) ◽  
pp. 2295-2299
Author(s):  
Elena Ionescu ◽  
Tanta Verona Iordache ◽  
Carmen Elena Tebrencu ◽  
Ruxandra Mihaela Cretu ◽  
Ana Mihaela Florea ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
Single Step ◽  
Anti Cancer ◽  
Hypericum Perforatum L

St. John s Wort (SJW) or Hypericum perforatum L. is a therapeutic plant highly used in pharmacology. Recent in vivo anti-cancer action of naphtodianthrones (NTs) has extended the research related to enrichment methodologies of SJW phyto-extracts. Therefore, the presented study pursuits the optimization of single-step extraction methodologies to obtain NTs-rich extracts from SJW.

Investigations on the in vivo wound healing potential of Hypericum perforatum L.

2010 ◽  
Vol 127 (2) ◽  
pp. 468-477 ◽  
Author(s):  
Ipek Peşin Süntar ◽  
Esra Küpeli Akkol ◽  
Demet Yılmazer ◽  
Turhan Baykal ◽  
Hasan Kırmızıbekmez ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hypericum Perforatum ◽  
Hypericum Perforatum L

Quantitation of oligomeric procyanidin clusters with defined degree of polymerisation from Hypericum perforatum L.

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
N Hellenbrand ◽  
F Petereit ◽  
M Lechtenberg ◽  
A Hensel
Keyword(s):  
Hypericum Perforatum ◽  
Degree Of Polymerisation ◽  
Hypericum Perforatum L

Determination of Hypericin in St. John's Wort (Hypericum perforatum L.) extracts using HPLC-ED

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
E Sofic ◽  
A Copra Janicijevic ◽  
M Maksimovic ◽  
I Tahirovic ◽  
L Klepo ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
St John’S Wort ◽  
St John's Wort ◽  
Hypericum Perforatum L

Kutane antioxidative Wirkung von Johanniskrautextrakt (Hypericum perforatum): In-vitro-, Ex-vivo- und In-vivo-Untersuchungen

2012 ◽  
Vol 33 (S 01) ◽  
Author(s):  
MC Meinke ◽  
S Schanzer ◽  
S Arndt ◽  
A Kleemann ◽  
J Lademann
Keyword(s):  
Hypericum Perforatum ◽  
Ex Vivo ◽  
Antioxidative Wirkung

Protective Effect of Hypericum perforatum L. Extract on Hexavalent Chromium Induced Toxicity in Rat Adrenal Gland

2017 ◽  
Vol 68 (9) ◽  
pp. 2014-2017
Author(s):  
Jelena Savici ◽  
Oana Maria Boldura ◽  
Cornel Balta ◽  
Diana Brezovan ◽  
Florin Muselin ◽  
...  
Keyword(s):  
Drinking Water ◽  
Adrenal Gland ◽  
Hexavalent Chromium ◽  
Structural Damage ◽  
Hypericum Perforatum ◽  
Adrenal Glands ◽  
Expression Level ◽  
Apoptotic Pathway ◽  
Hypericum Perforatum L ◽  
Induction Of Apoptosis

This study was carried out to test the possibility of hexavalent chromium administration through drinking water to induce the structural damage in rat�s adrenal glands and the possibility of Hypericum perforatum extract to faith against chromium aggression. Chromium induced cellular stress was determined by the expression level assessment of the Bcl2 genes family, known to modulate the apoptotic pathway. Obtained results showed that exposure to chromium altered adrenal glands morphology, by induction of apoptosis. When Hypericum perforatum extract was administered expression level of Bcl2 genes and histological lesions in adrenal glands were significantly reduced.

Evaluating the Content of Active Principles from Wild Hypericum perforatum L. in Various Harvesting Seasons

2018 ◽  
Vol 69 (7) ◽  
pp. 1892-1897
Author(s):  
Elena Ionescu ◽  
Tanta Verona Iordache ◽  
Carmen Elena Tebrencu ◽  
Ruxandra Mihaela Cretu ◽  
Ana Mihaela Florea ◽  
...  
Keyword(s):  
Plant Material ◽  
Hypericum Perforatum ◽  
Hypericum Perforatum L

Hypericum perforatum L., traditionally called St. John�s Wort has been used for decades as a phyto-therapeutic herb due to antidepressant, antimicrobial and antiseptic properties. As a result, the presented study evaluates the influence of the harvesting season for the Hypericum perforatum L. plant material, which is crucial for obtaining significant amounts of active principles.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

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