scholarly journals The Association between Body Mass Index and Mortality on Peritoneal Dialysis: A Prospective Cohort Study

2014 ◽  
Vol 34 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Yong Kyun Kim ◽  
Su-Hyun Kim ◽  
Hyung Wook Kim ◽  
Young Ok Kim ◽  
Dong Chan Jin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Cox Regression ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Cox Regression Analysis

BackgroundPrevious studies have demonstrated that increased body mass index (BMI) is associated with decreased mortality in hemodialysis (HD) patients. However, the association between BMI and survival has not been well established in patients undergoing peritoneal dialysis (PD). The aim of the study was to determine the association between BMI and mortality in the PD population using the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD) cohort in Korea.MethodsPrevalent patients with PD were selected from the CRC registry for ESRD, a prospective cohort study on dialysis patients in Korea. Patients were categorized into four groups by quartiles of BMI. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a BMI of quartile 2 (21.4 - 23.5 kg/m2) as the reference.ResultsA total of 900 prevalent patients undergoing PD were included. The median follow-up period was 24 months. The multivariate Cox proportional hazard model showed that the lowest quartile of BMI was associated with higher mortality (HR 3.00,95% confidence interval (CI), 1.26 - 7.15). However, the higher quartiles of BMI were not associated with mortality compared with the reference category of BMI quartile 2 (Quartile 3: HR 1.11, 95% CI, 0.43 - 2.85, Quartile 4: H R 1.64,95% CI, 0.66 - 4.06) after adjustment for clinical variables.ConclusionsLower BMI was a significant risk factor for death, but increased BMI was not associated with mortality in Korean PD patients.

scholarly journals Serum magnesium and cardiovascular mortality in peritoneal dialysis patients: a 5-year prospective cohort study

2018 ◽  
Vol 120 (4) ◽  
pp. 415-423 ◽  
Author(s):  
Hongjian Ye ◽  
Peiyi Cao ◽  
Xiaodan Zhang ◽  
Jianxiong Lin ◽  
Qunying Guo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peritoneal Dialysis ◽  
Prospective Cohort Study ◽  
Cardiovascular Mortality ◽  
Prospective Cohort ◽  
Cox Regression ◽  
Serum Magnesium ◽  
Study Endpoint ◽  
Lower Serum ◽  
All Cause Mortality

AbstractThe aim of this study was to explore the association between serum Mg and cardiovascular mortality in the peritoneal dialysis (PD) population. This prospective cohort study included prevalent PD patients from a single centre. The primary outcome of this study was cardiovascular mortality. Serum Mg was assessed at baseline. A total of 402 patients (57 % male; mean age 49·3±14·9 years) were included. After a median of 49·9 months (interquartile range: 25·9–68·3) of follow-up, sixty-two patients (25·4 %) died of CVD. After adjustment for conventional confounders in multivariate Cox regression models, being in the lower quartile for serum Mg level was independently associated with a higher risk of cardiovascular mortality, with hazards ratios of 2·28 (95 % CI 1·04, 5·01), 1·41 (95 % CI 0·63, 3·16) and 1·62 (95 % CI 0·75, 3·51) for the lowest, second and third quartiles, respectively. A similar trend was observed when all-cause mortality was used as the study endpoint. Further analysis showed that the relationships between lower serum Mg and higher risk of cardiovascular and all-cause mortality were present only in the female subgroup, and not among male patients. The test for interaction indicated that the associations between lower serum Mg and cardiovascular and all-cause mortality differed by sex (P=0·008 andP=0·011, respectively). In conclusion, lower serum Mg was associated with a higher risk of cardiovascular and all-cause mortality in the PD population, especially among female patients.

scholarly journals Education as a moderator of genetic risk for higher body mass index: prospective cohort study from childhood to adulthood

2017 ◽  
Vol 42 (4) ◽  
pp. 866-871 ◽  
Author(s):  
K Komulainen ◽  
L Pulkki-Raback ◽  
M Jokela ◽  
L-P Lyytikäinen ◽  
N Pitkänen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Body Mass ◽  
Prospective Cohort Study ◽  
Genetic Risk ◽  
Prospective Cohort

scholarly journals P2-36 Body mass index and risk of incident ischaemic heart disease in women: a prospective cohort study

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A229-A229
Author(s):  
D. Canoy ◽  
B. J. Cairns ◽  
A. Balkwill ◽  
G. K. Reeves ◽  
J. Green ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Body Mass ◽  
Prospective Cohort Study ◽  
Prospective Cohort

scholarly journals Multifactorial individualised programme for hamstring muscle injury risk reduction in professional football: protocol for a prospective cohort study

2020 ◽  
Vol 6 (1) ◽  
pp. e000758
Author(s):  
Johan Lahti ◽  
Jurdan Mendiguchia ◽  
Juha Ahtiainen ◽  
Luis Anula ◽  
Tuomas Kononen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Risk Reduction ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Injury Risk ◽  
Cox Regression ◽  
University Hospital ◽  
Professional Football ◽  
Hamstring Muscle ◽  
Cox Regression Analysis

IntroductionHamstring muscle injuries (HMI) continue to plague professional football. Several scientific publications have encouraged a multifactorial approach; however, no multifactorial HMI risk reduction studies have been conducted in professional football. Furthermore, individualisation of HMI management programmes has only been researched in a rehabilitation setting. Therefore, this study aims to determine if a specific multifactorial and individualised programme can reduce HMI occurrence in professional football.Methods and analysisWe conducted a prospective cohort study over two seasons within the Finnish Premier League and compare the amount of HMI sustained during a control season to an intervention season. Injury data and sport exposure were collected during the two seasons (2019–2020), and a multifactorial and individualised HMI risk reduction programme will be implemented during intervention season (2020). After a hamstring screening protocol is completed, individual training will be defined for each player within several categories: lumbo-pelvic control, range of motion, posterior chain strength, sprint mechanical output and an additional non-individualised ‘training for all players’ category. Screening and respective updates to training programmes were conducted three times during the season. The outcome will be to compare if there is a significant effect of the intervention on the HMI occurrence using Cox regression analysis.Ethics and disseminationApproval for the injury and sport exposure data collection was obtained by the Saint-Etienne University Hospital Ethics Committee (request number: IORG0007394; record number IRBN322016/CHUSTE). Approval for the intervention season was obtained from the Central Finland healthcare District (request and record number: U6/2019).

scholarly journals A Prospective Cohort Study of the Association Between Body Mass Index and Incident Bacterial Vaginosis

2019 ◽  
Vol 46 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Erica M. Lokken ◽  
Barbra A. Richardson ◽  
John Kinuthia ◽  
Khamis Mwinyikai ◽  
Amina Abdalla ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Bacterial Vaginosis ◽  
Body Mass ◽  
Prospective Cohort Study ◽  
Prospective Cohort
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