scholarly journals Effects of dermatan sulfate derivatives on platelet surface P-selectin expression and protein C activity in blood of inflammatory bowel disease patients

2004 ◽  
Vol 10 (23) ◽  
pp. 3485 ◽  
Author(s):  
Sheng-Li Ji
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Protein C ◽  
Dermatan Sulfate ◽  
Platelet Surface ◽  
Inflammatory Bowel ◽  
Protein C Activity

Expression of endothelial protein C receptor and thrombomodulin in the intestinal tissue of patients with inflammatory bowel disease

2004 ◽  
Vol 32 (Supplement) ◽  
pp. S266-S270 ◽  
Author(s):  
Elena M. Faioni ◽  
Stefano Ferrero ◽  
Gessica Fontana ◽  
Umberto Gianelli ◽  
Michele M. Ciulla ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Protein C ◽  
Endothelial Protein C Receptor ◽  
Intestinal Tissue ◽  
Inflammatory Bowel

scholarly journals Significance of IgA Anti-OmpC (Outer Membrane Protein C) Antibodies in Inflammatory Bowel Disease. A Single Centre Prospective Study

2011 ◽  
Vol 140 (5) ◽  
pp. S-638
Author(s):  
Stanislav Rejchrt ◽  
Marcela Drahosova ◽  
Darina Kohoutova ◽  
Jiri Cyrany ◽  
Tomáš Douda ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Membrane Protein ◽  
Prospective Study ◽  
Outer Membrane ◽  
Outer Membrane Protein ◽  
Bowel Disease ◽  
Protein C ◽  
Single Centre ◽  
Inflammatory Bowel

scholarly journals The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications

Blood ◽  
2010 ◽  
Vol 115 (6) ◽  
pp. 1121-1130 ◽  
Author(s):  
Silvio Danese ◽  
Stefania Vetrano ◽  
Li Zhang ◽  
Victoria A. Poplis ◽  
Francis J. Castellino
Keyword(s):  
Inflammatory Bowel Disease ◽  
Innate Immunity ◽  
Bowel Disease ◽  
Protein C ◽  
Inflammatory Diseases ◽  
Pathogenic Role ◽  
Chronic Inflammatory Diseases ◽  
Therapeutic Implications ◽  
Inflammatory Bowel ◽  
Cellular Components

Abstract Inflammation and coagulation are closely linked interdependent processes. Under physiologic conditions, the tissue microcirculation functions in anticoagulant and anti-inflammatory fashions. However, when inflammation occurs, coagulation is also set in motion and actively participates in enhancing inflammation. Recently, novel and unexpected roles of hemostasis in the humoral and cellular components of innate immunity have been described. In particular, the protein C system, besides its well-recognized role in anticoagulation, plays a crucial role in inflammation. Indeed, the protein C system is now emerging as a novel participant in the pathogenesis of acute and chronic inflammatory diseases, such as sepsis, asthma, inflammatory bowel disease, atherosclerosis, and lung and heart inflammation, and may emerge as unexpected therapeutic targets for intervention.

Thromboembolism and Resistance to Activated Protein C in Patients With Inflammatory Bowel Disease

1999 ◽  
Vol 94 (3) ◽  
pp. 685-690 ◽  
Author(s):  
Gottfried Novacek ◽  
Wolfgang Miehsler ◽  
Stylianos Kapiotis ◽  
Reinhold Katzenschlager ◽  
Wolfgang Speiser ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Protein C ◽  
Activated Protein C ◽  
Inflammatory Bowel

Resistance to activated protein C and low levels of free protein S in Greek patients with inflammatory bowel disease

2000 ◽  
Vol 95 (1) ◽  
pp. 190-194 ◽  
Author(s):  
I.E. Koutroubakis ◽  
A. Sfiridaki ◽  
I.A. Mouzas ◽  
A. Maladaki ◽  
A. Kapsoritakis ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Protein C ◽  
Activated Protein C ◽  
Protein S ◽  
Free Protein ◽  
Inflammatory Bowel ◽  
Low Levels

scholarly journals Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease

2007 ◽  
Vol 117 (7) ◽  
pp. 1951-1960 ◽  
Author(s):  
Franco Scaldaferri ◽  
Miquel Sans ◽  
Stefania Vetrano ◽  
Cristina Graziani ◽  
Raimondo De Cristofaro ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Crucial Role ◽  
Protein C ◽  
Inflammatory Bowel ◽  
Microvascular Inflammation
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