Congenital Granular Cell Epulis: A Rare Entity

Congenital granular cell epulis (CGCE) is a rare benign soft tissue lesion that usually originates from the neonatal gingiva and can lead to difficulty in breathing and feeding upon birth. This current case report describes a female newborn with a gingival mass that was identified by prenatal fetal ultrasonography. At birth, the oral mass was observed to protrude from the mouth, which adversely affected feeding. The lips could not be closed. The breathing was unaffected. Through a multidisciplinary team approach involving several healthcare professionals, the mass was successfully removed under general anaesthesia during an uncomplicated surgical procedure. Postoperative histopathological examination confirmed that the mass was a CGCE of the newborn. The infant recovered well after the operation.

Download Full-text

Gastric granular cell tumour, a rare entity

BMJ Case Reports ◽

10.1136/bcr-2018-227510 ◽

2019 ◽

Vol 12 (3) ◽

pp. e227510

Author(s):

Cláudia Santos ◽

Ana Virgínia Araújo ◽

Helena Contente ◽

Cláudia Branco

Keyword(s):

Oral Cavity ◽

Surgical Resection ◽

Clinical Case ◽

Subcutaneous Tissue ◽

Granular Cell ◽

The Body ◽

Cell Tumour ◽

Granular Cell Tumour ◽

Rare Entity ◽

Granular Cell Tumours

Granular cell tumours are rare neoplasms that may occur anywhere in the body. The most common locations are the oral cavity, skin and subcutaneous tissue, with only 8% of these tumours occurring at a gastrointestinal site. In the specific case of gastric granular cell tumours, only a few cases have been published until today. Granular cell tumours are usually benign; however, some malignant forms have been reported. Both endoscopic and surgical resection represent the treatment of choice. The authors report a new clinical case of a gastric granular cell tumour, treated with laparoscopic surgical resection, describing some endoscopic, imagiological and anatomopathological features.

Download Full-text

A study of cell proliferation using immunohistological staining: A case report of congenital granular cell epulis

International Journal of Pediatric Otorhinolaryngology ◽

10.1016/j.ijporl.2016.06.047 ◽

2016 ◽

Vol 88 ◽

pp. 58-62 ◽

Cited By ~ 3

Author(s):

Bo Zhang ◽

Xiaodan Tan ◽

Kunlun Zhang ◽

Yanchun Li ◽

Jingjing Chen ◽

...

Keyword(s):

Cell Proliferation ◽

Case Report ◽

Granular Cell ◽

Congenital Granular Cell Epulis ◽

Immunohistological Staining

Download Full-text

999 Case Report: A Rare Congenital Granular Cell Epulis In a Newborn Female Infant

British Journal of Surgery ◽

10.1093/bjs/znab259.351 ◽

2021 ◽

Vol 108 (Supplement_6) ◽

Author(s):

R O'Rorke ◽

D Ramkumar ◽

S Jones

Keyword(s):

Case Report ◽

Early Diagnosis ◽

Infant Feeding ◽

Benign Lesion ◽

Granular Cell ◽

Surgical Excision ◽

Excisional Biopsy ◽

Histopathological Analysis ◽

Anterior Maxilla ◽

Congenital Granular Cell Epulis

Abstract Background A congenital granular cell epulis (CGCE) is a rare benign lesion of uncertain histologic origin that is found on the mucosa of the alveolar ridges of newborn babies. There have been less than 250 reported cases of CGCE. They are most commonly found in the anterior maxilla region in female infants. Case Report An 8-week-old female was referred from the Neonatal team with a 10mmX5mm lesion found at birth on the mucosa of the anterior maxilla. She was seen in the Oral and Maxillofacial Department where her parents reported that the lesion was causing discomfort when feeding and they were keen for its removal. On initial medical examination the patient was diagnosed with a Grade 1 ejection systolic murmur and was awaiting further cardiac investigations. With this in mind and the young age of the patient, it was decided an excisional biopsy of the lesion under local anaesthesia (LA) would be the safest option. The lesion was excised uneventfully when the patient was 9 weeks old. It was shown to be a congenital granular cell epulis following histopathological analysis. The patient was reviewed 8 weeks post-operatively. There were no signs of recurrence, the infant’s feeding had improved drastically, and she was thriving. Discussion CGCE is a rare and interesting lesion in neonates. Early diagnosis and treatment of CGCE is essential in facilitating infant feeding. This report highlights that a well-planned surgical excision under LA is a well-tolerated and safer option which is welcomed by parents.

Download Full-text

Congenital granular cell epulis: a case report with immunohistochemistry

Erbil Dental Journal ◽

10.15218/edj.2021.07 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Payman Rashid

Keyword(s):

Case Report ◽

Granular Cell ◽

Congenital Granular Cell Epulis

Download Full-text

Whitish-Yellow Tumor on its Characteristic Cut Surface: A Case Report of Congenital Granular Cell Epulis

Clinical Pathology ◽

10.1177/2632010x19831257 ◽

2019 ◽

Vol 12 ◽

pp. 2632010X1983125

Author(s):

Kenichi Mizutani ◽

Munenori Mukai ◽

Hitoshi Nagatsuka ◽

Sohsuke Yamada

Keyword(s):

Case Report ◽

Cross Section ◽

Benign Lesion ◽

Granular Cell ◽

Typical Case ◽

Case Presentation ◽

Granular Cytoplasm ◽

Congenital Granular Cell Epulis ◽

Cut Surface ◽

Multiple Nodules

Introduction: Congenital granular cell epulis is a rare and benign lesion in newborn. There are some papers of the entity; however, there are very few reports focusing on its macroscopic view. Case Presentation: A 0-day-old boy was noted to have a mass consisting of multiple nodules on maxillary gingiva, and it was excised. The mass was measured about 2 cm in its greatest diameter. Surface of cross-section was characteristically whitish-yellow and very smooth. Histopathologically, the lesion was composed of a proliferation of large polygonal cells with demarcated cell membrane, granular cytoplasm, and small uniform nuclei. Immunohistochemically, these cells were negative for S100. The diagnosis was concluded as congenital granular cell epulis. Discussion and Conclusion: We reported a typical case of congenital granular cell epulis. It is noteworthy that the cross-section observed in this case was very characteristically whitish-yellow and smooth.

Download Full-text