scholarly journals Whitish-Yellow Tumor on its Characteristic Cut Surface: A Case Report of Congenital Granular Cell Epulis

2019 ◽  
Vol 12 ◽  
pp. 2632010X1983125
Author(s):  
Kenichi Mizutani ◽  
Munenori Mukai ◽  
Hitoshi Nagatsuka ◽  
Sohsuke Yamada
Keyword(s):  
Case Report ◽  
Cross Section ◽  
Benign Lesion ◽  
Granular Cell ◽  
Typical Case ◽  
Case Presentation ◽  
Granular Cytoplasm ◽  
Congenital Granular Cell Epulis ◽  
Cut Surface ◽  
Multiple Nodules

Introduction: Congenital granular cell epulis is a rare and benign lesion in newborn. There are some papers of the entity; however, there are very few reports focusing on its macroscopic view. Case Presentation: A 0-day-old boy was noted to have a mass consisting of multiple nodules on maxillary gingiva, and it was excised. The mass was measured about 2 cm in its greatest diameter. Surface of cross-section was characteristically whitish-yellow and very smooth. Histopathologically, the lesion was composed of a proliferation of large polygonal cells with demarcated cell membrane, granular cytoplasm, and small uniform nuclei. Immunohistochemically, these cells were negative for S100. The diagnosis was concluded as congenital granular cell epulis. Discussion and Conclusion: We reported a typical case of congenital granular cell epulis. It is noteworthy that the cross-section observed in this case was very characteristically whitish-yellow and smooth.

scholarly journals 999 Case Report: A Rare Congenital Granular Cell Epulis In a Newborn Female Infant

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
R O'Rorke ◽  
D Ramkumar ◽  
S Jones
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Infant Feeding ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Histopathological Analysis ◽  
Anterior Maxilla ◽  
Congenital Granular Cell Epulis

Abstract Background A congenital granular cell epulis (CGCE) is a rare benign lesion of uncertain histologic origin that is found on the mucosa of the alveolar ridges of newborn babies. There have been less than 250 reported cases of CGCE. They are most commonly found in the anterior maxilla region in female infants. Case Report An 8-week-old female was referred from the Neonatal team with a 10mmX5mm lesion found at birth on the mucosa of the anterior maxilla. She was seen in the Oral and Maxillofacial Department where her parents reported that the lesion was causing discomfort when feeding and they were keen for its removal. On initial medical examination the patient was diagnosed with a Grade 1 ejection systolic murmur and was awaiting further cardiac investigations. With this in mind and the young age of the patient, it was decided an excisional biopsy of the lesion under local anaesthesia (LA) would be the safest option. The lesion was excised uneventfully when the patient was 9 weeks old. It was shown to be a congenital granular cell epulis following histopathological analysis. The patient was reviewed 8 weeks post-operatively. There were no signs of recurrence, the infant’s feeding had improved drastically, and she was thriving. Discussion CGCE is a rare and interesting lesion in neonates. Early diagnosis and treatment of CGCE is essential in facilitating infant feeding. This report highlights that a well-planned surgical excision under LA is a well-tolerated and safer option which is welcomed by parents.

scholarly journals Prenatal diagnosis and multidisciplinary management: a case report of congenital granular cell epulis and literature review

2021 ◽  
Vol 49 (10) ◽  
pp. 030006052110537
Author(s):  
Yujiao Ye ◽  
Ruiqi Tang ◽  
Beibei Liu ◽  
Yi Li ◽  
Yunlu Mo ◽  
...  
Keyword(s):  
Case Report ◽  
Healthcare Professionals ◽  
Histopathological Examination ◽  
Granular Cell ◽  
Team Approach ◽  
Soft Tissue Lesion ◽  
Fetal Ultrasonography ◽  
Current Case ◽  
Multidisciplinary Team Approach ◽  
Congenital Granular Cell Epulis

Congenital granular cell epulis (CGCE) is a rare benign soft tissue lesion that usually originates from the neonatal gingiva and can lead to difficulty in breathing and feeding upon birth. This current case report describes a female newborn with a gingival mass that was identified by prenatal fetal ultrasonography. At birth, the oral mass was observed to protrude from the mouth, which adversely affected feeding. The lips could not be closed. The breathing was unaffected. Through a multidisciplinary team approach involving several healthcare professionals, the mass was successfully removed under general anaesthesia during an uncomplicated surgical procedure. Postoperative histopathological examination confirmed that the mass was a CGCE of the newborn. The infant recovered well after the operation.

scholarly journals Granular Cell Tumor of the Tongue: A Rare Case Presentation of a 14 Years Old Girl

2021 ◽  
pp. 1-2
Author(s):  
Mansour Nacouzi ◽  
Keyword(s):  
Granular Cell Tumor ◽  
Benign Neoplasm ◽  
Granular Cell ◽  
Cell Tumor ◽  
Lateral Border ◽  
Case Presentation ◽  
Granular Cytoplasm ◽  
The Right ◽  
Sixth Decade ◽  
Mobile Tongue

Granular cell tumor or Abrikossoff ’s tumor is an infrequent tumor that can arise in most organs, and especially in the ENT area. It is a usually benign neoplasm, that can lead to a misdiagnose of malignancy. It affects both sex, between the fourth and the sixth decade. We present in this report a case of a 14 years old girl with a slowly growing lesion on the right lateral border of the mobile tongue. The biopsy showed a proliferation of large cells with a granular cytoplasm that expressed two immunohistochemistry markers: CD68 and S100 antibodies. Surgical resection was completed with a one centimeter margin.The rare issue about this case is the age of presentation: the age of the patient is 14, whereas this tumor usually affects adult patients.

scholarly journals Periapical Cyst Following Replantation of Avulsed Teeth: A Case Report

2020 ◽  
pp. 1-6
Author(s):  
T. A. Oyedele ◽  
B. Sodipo ◽  
O. A. Adetayo ◽  
A. O. Ajimoko ◽  
E. Olawale
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Benign Lesion ◽  
Radiographic Examination ◽  
Dental Clinic ◽  
Case Presentation ◽  
Traumatic Injuries ◽  
Periapical Cyst ◽  
Histology Report

Introduction: Avulsion has been described as the traumatic displacement of the tooth out of the socket, and it accounts for 0.5% to 16% of traumatic injuries in the permanent dentition. Many complications have been associated with avulsed tooth following replantation. This paper aimed at presenting a case of the large cystic lesion following replantation of avulsed teeth. Case Presentation: A case of a 17-year-old undergraduate student who presented in the dental clinic for medical screening as a mandatory exercise upon gaining admission. During the examination, a purulent pus discharge was noticed on the labial sulcus about tooth 11. History revealed that she had avulsion of teeth 11 and 12 about 4-years earlier that was replanted and splinted for 2-3 weeks and subsequently she was discharged from the clinic without any further treatment. Radiographic examination revealed periapical radiolucency without well define margin about teeth 11 and 12. Periapical surgery was carried out and two large cystic cavities were seen at about teeth 11 and 12 during surgery. The histology report of the specimen revealed a benign lesion suggesting periapical cyst. Conclusion: There is the need for adequate follow-up and monitoring of replanted teeth the following avulsion to arrest any complication that might arise from the procedure. Also, the importance of endodontic treatment following replantation of the avulsed tooth cannot be overemphasized.

scholarly journals Granular Cell Tumour of The Vulva: A Case Report

1970 ◽  
Vol 3 (1) ◽  
pp. 28-30
Author(s):  
SM Khodeza ◽  
Nahar Begum ◽  
Nishat Begum
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Benign Lesion ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Duct Cyst ◽  
Clinical Presentations ◽  
Neural Origin ◽  
Granular Cell Tumours

Vulvar granular cell tumours are uncommon neoplasms of neural origin. The clinical presentations, surgical findings and histology of Granular Cell Tumour (GCT) of the vulva in a 50 year old lady is presented. Although rare, this benign lesion must be considered in the differential diagnosis of the labia majora masses, such as Bartholin,s duct cyst, Lipoma, Papilloma, Hydradenoma and Fibroma. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10111 AKMMCJ 2012; 3(1): 28-30

Congenital (Granular Cell) Epulis of the Newborn: A Case Report with Immunohistochemical Study on the Histogenesis

1999 ◽  
Vol 19 (6) ◽  
pp. 527-529 ◽  
Author(s):  
Pietro Leocata ◽  
Giuseppina Bifaretti ◽  
Solidea Saltarelli ◽  
Alfonso Corbacelli ◽  
Luca Ventura
Keyword(s):  
Case Report ◽  
Immunohistochemical Study ◽  
Granular Cell ◽  
Congenital Granular Cell Epulis

scholarly journals Congenital Granular Cell Epulis

2014 ◽  
Vol 138 (1) ◽  
pp. 128-131 ◽  
Author(s):  
Rachel Conrad ◽  
Mia C. N. Perez
Keyword(s):  
Granular Cell Tumor ◽  
Squamous Epithelium ◽  
Neuron Specific Enolase ◽  
Granular Cell ◽  
Cell Tumor ◽  
Alveolar Ridge ◽  
Careful Observation ◽  
Granular Cytoplasm ◽  
S 100 ◽  
Congenital Granular Cell Epulis

Congenital granular cell epulis is a rarely reported lesion of unknown histogenesis with a strong predilection for the maxillary alveolar ridge of newborn girls. Microscopically, it demonstrates nests of polygonal cells with granular cytoplasm, a prominent capillary network, and attenuated overlying squamous epithelium. The lesion lacks immunoreactivity for S-100, laminin, chromogranin, and most other markers except neuron-specific enolase and vimentin. Through careful observation of its unique clinical, histopathologic, and immunohistochemical features, this lesion can be distinguished from the more common adult granular cell tumor as well as other differential diagnoses.

scholarly journals Congenital granular cell epulis: A case series

2020 ◽  
Vol 9 ◽  
pp. 17
Author(s):  
Mustafa Okumuş ◽  
Adil Umut Zubarioğlu ◽  
Uğuray Payam Hacısalihoğlu
Keyword(s):  
Benign Lesion ◽  
Case Series ◽  
Granular Cell ◽  
Surgical Excision ◽  
Postoperative Recovery ◽  
Alveolar Ridge ◽  
Congenital Granular Cell Epulis ◽  
Malignant Lesions ◽  
Rule Out

Background: Congenital granular cell epulis (CGCE) is an extremely rare intraoral tumor of the newborn with a potential to disrupt feeding and produce respiratory distress. Case Series: We report two newborns presented with mass protruding off the mouth since birth. The mass was arising from alveolar ridge in both cases and dealt with surgical excision. Histopathology revealed it congenital granular cell epulis. Postoperative recovery and follow-up are uneventful. Conclusion: Congenital granular cell epulis is a benign lesion though not quite uncommon, may cause diagnostic challenges. Early excision and histopathology rule out malignant lesions.

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