scholarly journals BioMEMS for Life-Saving Biomedical Technologies

2021 ◽  
Vol 3 (3) ◽  
pp. 5-15
Author(s):  
Pallavi Tripathi ◽  

Lately, there have been huge research interests in developing micro-electro-mechanical systems (MEMS) for various biological and medical applications. These bioMEMS based devices are considered instrumental to develop many life-saving biomedical technologies. To this end, a number of studies have focused on the developments of bioMEMS in the field of molecular biology, biotechnology, medicine, biochemical and material sciences and also in microsystems technology. The applications of bioMEMS are extensive that include diagnostic research, drug delivery, therapeutics, tissue engineering, biosensors and lab-on-a-chip systems for regenerative medicine, to name a few. Here, we present a perspective on the important breakthroughs in bioMEMS including the advances in microfabrication, monitoring and modulating cellular activities along with notable applications of bioMEMS in the modern healthcare sector.

2000 ◽  
pp. 203-247 ◽  
Author(s):  
Vladimir N. Kestelman ◽  
Leonid S. Pinchuk ◽  
Victor A. Goldade

2018 ◽  
Vol 400 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Nagendra Kumar Kaushik ◽  
Bhagirath Ghimire ◽  
Ying Li ◽  
Manish Adhikari ◽  
Mayura Veerana ◽  
...  

Abstract Non-thermal atmospheric pressure plasma has been proposed as a new tool for various biological and medical applications. Plasma in close proximity to cell culture media or water creates reactive oxygen and nitrogen species containing solutions known as plasma-activated media (PAM) or plasma-activated water (PAW) – the latter even displays acidification. These plasma-treated solutions remain stable for several days with respect to the storage temperature. Recently, PAM and PAW have been widely studied for many biomedical applications. Here, we reviewed promising reports demonstrating plasma-liquid interaction chemistry and the application of PAM or PAW as an anti-cancer, anti-metastatic, antimicrobial, regenerative medicine for blood coagulation and even as a dental treatment agent. We also discuss the role of PAM on cancer initiation cells (spheroids or cancer stem cells), on the epithelial mesenchymal transition (EMT), and when used for metastasis inhibition considering its anticancer effects. The roles of PAW in controlling plant disease, seed decontamination, seed germination and plant growth are also considered in this review. Finally, we emphasize the future prospects of PAM, PAW or plasma-activated solutions in biomedical applications with a discussion of the mechanisms and the stability and safety issues in relation to humans.


Micromachines ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 695 ◽  
Author(s):  
Yunxia Wang ◽  
Yong Zhang ◽  
Zheng Qiao ◽  
Wanjun Wang

Homogeneous mixing of microscopic volume fluids at low Reynolds number is of great significance for a wide range of chemical, biological, and medical applications. An efficient jet mixer with arrays of micronozzles was designed and fabricated using additive manufacturing (three-dimensional (3D) printing) technology for applications in centrifugal microfluidic platforms. The contact surface of miscible liquids was enhanced significantly by impinging plumes from two opposite arrays of micronozzles to improve mixing performance. The mixing efficiency was evaluated and compared with the commonly used Y-shaped micromixer. Effective mixing in the jet mixer was achieved within a very short timescale (3s). This 3D printed jet mixer has great potential to be implemented in applications by being incorporated into multifarious 3D printing devices in microfluidic platforms.


2010 ◽  
Vol 49 (36) ◽  
pp. 6260-6266 ◽  
Author(s):  
Alistair C. McKinlay ◽  
Russell E. Morris ◽  
Patricia Horcajada ◽  
Gérard Férey ◽  
Ruxandra Gref ◽  
...  

Endocrinology ◽  
2010 ◽  
Vol 151 (2) ◽  
pp. 458-465 ◽  
Author(s):  
Banu S. Zolnik ◽  
África González-Fernández ◽  
Nakissa Sadrieh ◽  
Marina A. Dobrovolskaia

Today nanotechnology is finding growing applications in industry, biology, and medicine. The clear benefits of using nanosized products in various biological and medical applications are often challenged by concerns about the lack of adequate data regarding their toxicity. One area of interest involves the interactions between nanoparticles and the components of the immune system. Nanoparticles can be engineered to either avoid immune system recognition or specifically inhibit or enhance the immune responses. We review herein reported observations on nanoparticle-mediated immunostimulation and immunosuppression, focusing on possible theories regarding how manipulation of particle physicochemical properties can influence their interaction with immune cells to attain desirable immunomodulation and avoid undesirable immunotoxicity.


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