Geometric Analysis and Modelling of Microfluidic Contact Angles for Design and Manufacturing of Micro Bio-Device

Author(s):  
Yuan-Shin Lee ◽  
Euiseok Kim ◽  
Roger J. Narayan
Author(s):  
D.F. Clapin ◽  
V.J.A. Montpetit

Alzheimer's disease is characterized by the accumulation of abnormal filamentous proteins. The most important of these are amyloid fibrils and paired helical filaments (PHF). PHF are located intraneuronally forming bundles called neurofibrillary tangles. The designation of these structures as "tangles" is appropriate at the light microscopic level. However, localized domains within individual tangles appear to demonstrate a regular spacing which may indicate a liquid crystalline phase. The purpose of this paper is to present a statistical geometric analysis of PHF packing.


1976 ◽  
Vol 55 (2) ◽  
pp. 67
Author(s):  
C.A. Gladman ◽  
R.A. Williams
Keyword(s):  

TAPPI Journal ◽  
2016 ◽  
Vol 15 (4) ◽  
pp. 253-262 ◽  
Author(s):  
ERIK BOHLIN ◽  
CAISA JOHANNSON ◽  
MAGNUS LESTELIUS

The effect of coating structure variations on flexographic print quality was studied using pilot-coated paperboard samples with different latex content and latex particle sizes. Two latexes, with particle sizes of 120 nm and 160 nm, were added at either 12 parts per hundred (pph) or 18 pph to the coating formulation. The samples were printed with full tone areas at print forces of 25 N and 50 N in a laboratory flexographic printing press using a waterbased ink. A high ratio of uncovered areas (UCAs) could be detected for the samples that contained 18 pph latex printed at a print force of 25 N. UCAs decreased with increased print force and with decreased amounts of latex in the coating formulation. The fraction of latex covered area on the coating surface was estimated to be 0.35–0.40 for the 12 pph, and 0.70–0.75 for the 18 pph samples. The ink penetration depth into the coating layer could be linked to the fraction of latex-free areas on the coating surface. Optical cross section microscopy indicated that a higher printing force did not increase the depth of penetrated ink to any greater extent. Higher printing force did increase contact between plate and substrate, leading to an improved distribution of the ink. This, in turn, increased print density and decreased UCAs. On closer inspection, the UCAs could be categorized as being induced by steep topographic changes. When appearing at other locations, they were more likely to be caused by poor wetting of the surface. To understand the wetting behavior of the coating surface, observed contact angles were compared with calculated contact angles on surfaces of mixed composition.


TAPPI Journal ◽  
2009 ◽  
Vol 8 (2) ◽  
pp. 33-38 ◽  
Author(s):  
ANNA JONHED ◽  
LARS JÄRNSTRÖM

The aim of this study was to investigate the properties of hydrophobically modified (HM) quaterna-ry ammonium starch ethers for paper sizing. These starches possess temperature-responsive properties; that is, gelation or phase separation occurs at a certain temperature upon cooling. This insolubility of the HM starches in water at room temperature improved their performance as sizing agents. The contact angles for water on sized liner were substantially larger than on unsized liner. When the application temperature was well above the critical phase-separation temperature, larger contact angles were obtained for liner independently of pH compared with those at the lower application temperature. Cobb60 values for liner decreased upon surface sizing, with a low pH and high application temperature giving lower water penetration. Contact angles on greaseproof paper decreased upon sur-face sizing as compared to unsized greaseproof paper, independently of pH and temperature. Greaseproof paper showed no great difference between unsized substrates and substrates sized with HM starch at different pH. This is probably due to the already hydrophobic nature of greaseproof paper. However, the Cobb60 values increased at low pH and low application temperature. Surfactants were added to investigate how they affect the sized surface. Addition of surfactant reduces the contact angles, in spite of indications of complex formation.


2014 ◽  
Vol 1 (1) ◽  
pp. 365-368
Author(s):  
Ionela Magdalena Rotaru ◽  
Sorin Borza

Abstractthe paper continues the research started in the paper “Conception and fabrication using knowledge management principles”. The theoretical guidelines found in the mentioned paper crystallises at a practical level in an original product – a software solution. The proposed solution has as a central element notion concerning the design and manufacturing of straight axes in the automotive industry. The application field for the proposed example regards the educational area; the software guides the user by theoretical concepts, examples, problems through practical aspects concerning the design and manufacturing of a part belonging to the axes family specific to the automotive industry. The software was developed using the Access work environment.


2021 ◽  
Author(s):  
Cole Dunning ◽  
Rodrigo Cervantes ◽  
Lorena Velasquez ◽  
Anastasia Western ◽  
Michelle Sherman ◽  
...  

2016 ◽  
Vol 10 (2) ◽  
pp. 162-171
Author(s):  
Hafid Hafid ◽  
Tatang Sutisna

The design and manufacturing of the rotary table with the specification Ø 170 mm (6 inches) for CNC machine 4 axis has been done. The objective of manufacturing a rotary table is to increase the efficiency of CNC machine Hardford 4 axis to be above 80% in line machining center CV. IM’s workshop. The engineering methods was taken, consist of: working preparation, manufacturing of working drawing, engineering process, the manufacturing and testing. The prototype has been tested and operated, the resulting of increasing productivity of which were as follows: the process of assembling was increased to be 3 time ( before 1 time) and processing time for a specific case reduced from 5 hours to 3 hours, number of operators for the case of assembling the rotary reduced to 1 person (before 4 persons), safety and security become to be better. The results show increased efficiency of CNC machine Hardford, from under 50% to be above 80%. Based on the economical analysis obtained by the cost of good sold (C.G.S) of the rotary table is IDR 34.060.000. The results presented in this paper is expected to be case study for developing a business of the metal and engineering SMEs domestic to the effort of improving efficiency, quality, productivity and competitiveness in global market.ABSTRAKPerancangan dan pembuatan alat bantu meja putar (rotary table) dengan spesifikasi teknis Ø 170 mm (6 inci) untuk mesin CNC 4 axis telah dilakukan. Tujuan pembuatan rotary table adalah untuk meningkatkan efisiensi mesin CNC Hardford 4 axis di atas 80% pada line machining center Bengkel CV. IM. Metode rancang bangun yang dilakukan, meliputi: persiapan kerja, pembuatan gambar kerja, proses engineering, pembuatan dan uji coba. Prototip tersebut telah diuji coba dan dioperasikan dengan hasil peningkatan produktivitas sebagai berikut: proses pengerjaan bongkar pasang meningkat menjadi 3 kali (sebelumnya 1 kali) dan waktu pengerjaan untuk kasus tertentu berkurang dari 5 jam menjadi 3 jam, jumlah operator untuk kasus bongkar pasang rotary berkurang menjadi 1 orang (sebelumnya 4 orang), keselamatan kerja dan keamanan menjadi lebih baik. Hasil peningkatan berupa efisiensi mesin CNC Hardford 4 axis dari sebelumnya di bawah 50% menjadi di atas 80%. Berdasarkan hasil perhitungan analisis ekonomi diperoleh harga pokok produksi (HPP) alat bantu meja putar adalah sebesar Rp. 34.060.000. Bahasan ini diharapkan menjadi contoh kasus bagi pengembangan usaha IKM logam dan mesin dalam negeri untuk meningkatkan efisiensi, mutu, produktivitas dan keunggulan daya saing di pasar global.Kata kunci: alat bantu meja putar, mesin CNC, harga pokok produksi


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