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2021 ◽  
Vol 45 (1) ◽  
pp. 24-37
Author(s):  
Pamela Bailey ◽  
Jane L. Newman

A 9th grade Honors English class creates and publishes original poems, art, fiction, and nonfiction products through an activity called “Type Three – Twenty Time = T4.” The instructional method merges elements from Renzulli’s Type III process with elements from Brookhouser’s 20Time Project-based learning model. Each student researches an interest passion topic and creates a related original product or service for a real audience. Upon reflection on the experience, the author identifies evidence-based practices including compacting ELA course content to create time for the T4 process; enhanced student engagement; active learning versus passive learning; improved writing skills; quality presentation skills; higher level creative and critical thinking; and upgraded 21st Century skills.


2021 ◽  
Vol 127 (3) ◽  
Author(s):  
Nguyen Quang Dieu ◽  
Tang Van Long

In this note, we establish a product property for $P$-extremal functions in the same spirit as the original product formula due to J. Siciak in Ann. Polon. Math., 39 (1981), 175–211. As a consequence, we obtain convexity for the sublevel sets of such extremal functions. Moreover, we also generalize the product property of $P$-extremal functions established by L. Bos and N. Levenberg in Comput. Methods Funct. Theory 18 (2018), 361–388, and later by N. Levenberg and M. Perera, in Contemporary Mathematics 743 (2020), 11–19, in which no restriction on $P$ is needed.


Author(s):  
I. Camps Gamundi

In the summer of 1830 Charles Lyell carried out an expedition through Catalonia with the aim of learning about Olot volcanism. The most important route starts in Barcelona and reaches Ceret (Vallespir, Northern Catalonia), passing through high-value of geological and landscape such as Montjuïc, Montserrat, Súria, Cardona, the Lluçanès, the Vic plain, the Cabrerès, the Garrotxa volcanic area and the Salines massif. The implementation of a long-distance route similar to other thematic paths and focused on the teaching of geology and the interpretation of the landscape while following in the footsteps of this expedition (Lyell Route) can generate an original product in the line of sustainable tourism. This itinerary would bring socio-economic and scientific-cultural benefits to the territories through which it passes and to society as a whole. Finally, it is clear that to carry out this project optimally requires solid and assertive collaboration between different geological and environmental actors, especially those who develop their activity on the territory of the Lyell Route.


2021 ◽  
Vol 6 (3) ◽  
Author(s):  
Marina Timofeeva ◽  
Stanislav Churakov

The article presents the results of the study of ethnocultural values in the strategy of creating an author's brand. Topical aspects are formulated that form the resources of the brand of the future, with the potential of a sustainable business idea working ahead of schedule. The relevance of the studied topic is revealed in connection with the request of the target audience for self-identification, the need for an original product and the aesthetic value of this product in the fashion industry. And also the emergence of interest in local cultures, as a result — in local brands, and the interaction of identity and competition. It also considers the aspect of emotional satisfaction and the departure from the realities of life's problems through narratives, which resulted in the processes of forming a new reality that affect the whole industry, and an appeal to cultural traditions. The authors analyze the formation of the connection of identities with territory, ecology, psychology, culture, economics. Is considered the influence of tradition and fashion on the landscape of the cultural map of the world. When designers not only create the visual language and design codes of our time, but also preserve the traditional values of folk culture, create a connection with history, invest new meanings in modern fashion, and respond to the requests of entire generations. The article describes the main problems and tasks that the designer should take into account, choosing ethnic conception as the main idea of the brand. The theoretical and applied significance of the work is that the study creates a model of the value of cultural meanings for implementation commercial projects. The work contains illustrative material that renders examples of working with references and using them when creating collections.


Author(s):  
Anshi Mehra ◽  
Hemanreet Kaur ◽  
Anoor Fatima ◽  
Aman Noor ◽  
Khushi Gupta ◽  
...  

A biosimilar is the new emerging drug product of the sector of Biologics that comes under speedily evolving area of pharmaceutical industry. It is the generic substitute for original research-based drugs. Since the Biologics are produced by a variety of products more commonly including cells extracted from humans, animals, microorganisms which varies phenotypically therefore they are “similar but not same” to the original product. Being a new product, it produces several challenges in the market including its regulation guidelines, production efficiency, quality management, and safety factors etc. The quality of these products along with its effectiveness and reduced costs are making them more and more popular. Different research is still being going on for enhancing the efficacy of biosimilars due to its more and more usage in the market. Several countries have developed their separate norms for the production and clinical usage of these biosimilars constituting Canada, Japan, Korea, and United States of America etc. The more biologics grab the attention of the eminent scientists for better innovations, the less marketing approval it gets. To enhance such a situation U S Congress passed the Biologics Price Competition and Innovation act 2009 and US FDA allowed “abbreviated pathway” for their approval and India being the most suited manufacturing area has also prepared certain guidelines stated as “Draft Guidelines on Similar Biologics” which were announced in June 2012, by Department of Biotechnology at Boston bio. The regulatory environment for biosimilars continues to evolve, both in recognition of advances in technology/ analytical methods and the availability of new targets for biosimilar development. With the advent of such efforts biosimilars are trying to surround the market. The demanding sector of biosimilars reveals the challenging gateway towards the nanomedicines also which shows that with the advancing biotechnology after these biosimilars, we are heading towards other newly biologically derived products.           


2021 ◽  
Vol 4 (6(112)) ◽  
pp. 41-50
Author(s):  
Kirill Ostrovnoy ◽  
Antonina Dyuryagina ◽  
Alexandr Demyanenko ◽  
Vitaliy Tyukanko

This paper reports the results of studying the influence of surfactants (SAS) on the wetting of titanium dioxide in alkyd paint and varnish materials (PVM), based on pentaphthalic (PPh) and alkyd-urethane (AU) film-forming substances. Edge wetting angle (θ°) and adhesion work (Wa) were used as the criteria for assessing the wettability of titanium dioxide. Three additives were used as SAS: the original product AS-1, obtained from waste of oil refining (with low cost), and industrial additives: "Telaz" and polyethylene polyamine (PEPA). All the studied additives in PPh and AU PVM improve the wetting of titanium dioxide. At the 30 % content of AS film-forming substance in the composition, the maximum decrease in θ° for AS-1 is 4.5°, for PEPA and Telaz it is 4°. For pentaphthalic composition under similar conditions, a decrease in edge wetting angle for AS-1 is 10 °, for Telaz 8.6°, and for PEPA 5.9°. According to the relative change in edge wetting angle for both systems, the maximum decrease in θ° is about 10 %. The introduction of SAS into the composition of AU ambiguously affects the adhesion work, for PPh, the introduction of SAS causes a decrease in adhesion work (Wa). AS-1 is the SAS that minimally reduces adhesion work. The compositions of the PVM by the method of probabilistic-deterministic planning, which ensures maximum wetting of titanium dioxide with film-forming solutions, were analyzed. The equations for calculating the edge angle of wetting of titanium dioxide depending on the content of solvent and the SAS in the PVM were derived. The effectiveness of the AS-1 product as a wetting additive for alkyd paints and varnishes was proven. The wetting ability of the original SAS – AS-1 is close to industrial additives PEPA and Telaz.


2021 ◽  
Vol 11 (16) ◽  
pp. 7622
Author(s):  
Efterpi Bouroutzika ◽  
Stavros Proikakis ◽  
Athanasios K. Anagnostopoulos ◽  
Angeliki I. Katsafadou ◽  
George C. Fthenakis ◽  
...  

Cheese is a worldwide produced and consumed commodity. There are many varieties of cheese from soft to hard, white to yellow, and fresh to aged after ripening. Especially, each category has its own producing technology. Many countries have labeled their most traditional cheese as Protective Designation of Origin (PDO). Moreover, several studies using advanced technologies, such as proteomics, have been performed to enhance labeling. In this review, broadly diffused and marketed, as well as Mediterranean countries’ special interest in Mediterranean diet-related PDO cheeses have been chosen as a reference. The aim of this work was to highlight the use of proteomics methods to examine how cheese proteins and peptides rearrange after ripening and use of starters. Further, we aimed to examine what kind of proteins are produced. Finally, we focused on bioactive molecules in cheeses and distinction of the original product from its counterfeit.


Author(s):  
Yevhen Pavlenko ◽  
Vladimir Butenko ◽  
Vadim Gubin ◽  
Serhii Lubenets

The paper deals with the problems of increasing the efficiency of software development, in particular, the issue of reducing the time for developing programs and using automated synthesis of programs, which will avoid the revision of the original product. The software should be tested along with other system components in all combinations that may occur. Testing is time-consuming because hidden bugs are revealed through unexpected interactions between software components. With structural analysis, data flow diagrams are not the end result, they are a developer tool. First, diagrams are built, and then mechanisms are developed to ensure the required system behavior. A graphical approach to solving the problem of automation of software development is being developed, based on the involvement of visual forms of program presentation. For any program object, you can select a finite number of states in which it is at each moment of time. The program progress is associated with the transition of an object from one state to another. The graph replaces the textual form of the description of the program algorithm, while the visual representation of the algorithm is realized. The specification of data structures, as well as the setting of intermodular interfaces according to data, is separated from the description of the structure of the algorithm and controls. Basic modules and data types are used. Basic modules are local calculable functions, on the basis of which all other technology objects are generated. Data types describe the syntactic and semantic aspects of constructing data used in base functions. Algorithms for finding routes on directed graphs are considered. When defining routes from the root vertex to the final ones, the properties of the algebra of three-valued logic were used. Based on the considered approach, as well as taking into account its shortcomings, a method for classifying data types was proposed, based on the implementation of a partial enumeration of the routes of the graph of program links and a method for designing software based on it, taking into account minimizing the time and cost of the project. Keywords: software, computer engineering, information systems, components, partial enumeration of graph routes, development costs.


2021 ◽  
Vol 10 (1) ◽  
pp. 1-10
Author(s):  
Virgil Florescu ◽  
Ștefan Mocanu ◽  
Ancuța Neagu ◽  
Cristina Sescu-Gal

Abstract Estimating the remaining service life of a forklift for an objective reference is not only a requirement of the applicable legislation but also represents a challenge for specialized technical staff. It is well known that the first fatigue failure element of a forklift is its fork. A simulation using the SolidWorks suite and its result is presented in this article. It allows the identification of critical areas of fatigue failure. Based on the design of the subassembly and the loading scheme of the original product, the model under analysis with finite element was made on a 1: 1 scale. The filet areas also required a comparative analysis of the results obtained depending on the choice of mesh and discretization element. Starting from the mechanical properties of the material as well as the association with the characteristic fatigue yield curves (Wohler), a method for estimating the remaining service life of the structure is proposed. The aspect related to obtaining exact results without an excessive consumption of computing resources was also taken into account.


2021 ◽  
Vol 447 (3) ◽  
pp. 103-110
Author(s):  
B.T. Yermagambet ◽  
M.K. Kazankapova ◽  
A.T. Nauryzbayeva ◽  
Zh.M. Kassenova

The article describes a method for obtaining carbon nanofibers (CNFs) based on humic acid from oxidized coal of the Maikuben basin and polycarlonitrile (PAN) by electrospinning in laboratory conditions. The value of the interelectrode voltage was 20-25 kV. The elemental composition was determined and the surface morphology of the studied sample was studied, the type of modification of the carbon fiber was revealed. As a result of energy dispersive X-ray spectroscopy and scanning electron microscopy (SEM), the chemical composition of the initial CNF (C-48.73%) and the diameter of carbon fibers, which ranged from 148.6 nm to 1.36 μm, were found. The processes of oxidation and carbonization of the obtained samples were also carried out. The elemental composition of carbon after oxidation and carbonization was 87.75 and 89.16%, respectively, the diameter of the fibers was 117.5 nm -1.03 microns. The results of Raman scattering of light (RS) of carbonized CNF showed the degree of graphitization - 23.97%, the ratio I (D) / I (G) = 0.7, I (G) / I (D) = 1.4. The resistance of this material was 27 ohms. On the basis of SEM patterns of CNFs based on humic acid and PAN, it was found that the structure of the sample after oxidation and carbonization retains the original fibrous structure. It was also found that the diameter of nanofibers decreases from 1 μm to 117.5 nm, which may be associated with the release of volatile and heterogeneous components of the original product and the formation of a more structural thin porous filament.


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