scholarly journals Primary Pancreatic Diffuse Large B-Cell Lymphoma Involving the Stomach

2020 ◽  
Vol 95 (4) ◽  
pp. 281-286
Author(s):  
Ji Young Park ◽  
Tae Joo Jeon
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Epigastric Pain ◽  
B Cell Lymphoma ◽  
Needle Aspiration ◽  
Pancreatic Mass ◽  
Upper Gastrointestinal Endoscopy ◽  
Rare Presentation ◽  
Pancreas Head ◽  
Pancreatic Lymphoma ◽  
Upper Gastrointestinal

Primary pancreatic lymphoma (PPL) is extremely rare, comprising fewer than 1% of non-Hodgkin lymphomas. The most common histological subtype of PPL is diffuse large Bcell lymphoma (DLBCL). A 46-year-old man presented with indigestion, epigastric pain, and weight loss for 2 months. Abdominal computed tomography showed a well-defined hypodense mass located at the pancreas head involving the stomach, as well as enlargement of several mesenteric and perigastric lymph nodes. Histological examination was performed by upper gastrointestinal endoscopy of the stomach and endoscopic ultrasound-guided fine-needle aspiration and biopsy of the pancreatic mass. Histology of the pancreatic mass and the stomach revealed pancreatic DLBCL, involving the stomach. The patient received chemotherapy and is currently in complete remission. We report a rare presentation of DLBCL, appearing as a primary pancreatic tumor involving the stomach, which we presume is the first such report in South Korea.

scholarly journals A Pancreatic Inflammatory Myofibroblastic Tumor with Spontaneous Remission: A Case Report with a Literature Review

Diagnostics ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 150 ◽  
Author(s):  
Hiroyuki Matsubayashi ◽  
Katsuhiko Uesaka ◽  
Keiko Sasaki ◽  
Seitaro Shimada ◽  
Kazunori Takada ◽  
...  
Keyword(s):  
Inflammatory Myofibroblastic Tumor ◽  
Gastrointestinal Endoscopy ◽  
Fine Needle Aspiration Biopsy ◽  
Submucosal Tumor ◽  
Spontaneous Remission ◽  
Needle Aspiration ◽  
Eosinophil Infiltration ◽  
Upper Gastrointestinal Endoscopy ◽  
Pancreas Head ◽  
Upper Gastrointestinal

The inflammatory myofibroblastic tumor (IMT) is a rare tumor that can develop in any systemic organ. Its features are generally benign, but it often resembles malignancies and is treated surgically. Our patient was an 82-year-old female complaining of abdominal discomfort. Computed tomography demonstrated a 5 cm, ill-enhanced mass at the pancreas head. Upper gastrointestinal endoscopy revealed a duodenal submucosal tumor with apical erosion. Endoscopic ultrasonography (EUS) demonstrated a heterogeneous, low-echoic pancreas mass without clear margins. Fine-needle aspiration biopsy (FNAB) demonstrated spindle myofibroblastic tissues with lymphoplasmacyte and eosinophil infiltration, confirming an IMT diagnosis. Surprisingly, the tumor spontaneously regressed in one month without medication. Histological diagnosis using EUS-FNAB is essential for the rare pancreatic solid tumor like IMT.

A Case of Primary Pancreatic non-Hodgkin B-cell Lymphoma Mimicking Autoimmune Pancreatitis

2015 ◽  
Vol 24 (2) ◽  
pp. 245-248
Author(s):  
Andrea Anderloni ◽  
Chiara Genco ◽  
Marco Ballarè ◽  
Stefania Carmagnola ◽  
Serena Battista ◽  
...  
Keyword(s):  
Autoimmune Pancreatitis ◽  
Gastrointestinal Endoscopy ◽  
B Cell Lymphoma ◽  
Upper Gastrointestinal Endoscopy ◽  
Non Hodgkin Lymphoma ◽  
Pancreatic Masses ◽  
Pancreatic Lymphoma ◽  
Upper Gastrointestinal ◽  
Tomography Scan ◽  
Primary Pancreatic Lymphoma

Non Hodgkin lymphoma frequently involves the gastrointestinal tract, in particular the stomach and the small bowel. Rarely, it can also be a cause of pancreatic masses. Clinical presentation is often non-specific and may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. We report a case of primary pancreatic lymphoma in a young woman with jaundice, fever and abdominal pain mimicking autoimmune pancreatitis. Clinical evaluation included the abdominal Computed Tomography scan, Magnetic Resonance Imaging and an upper gastrointestinal endoscopy that revealed a large duodenal mass. Endoscopic biopsies were performed and eventually histological examination was coherent with a diagnosis of primary pancreatic lymphoma.

scholarly journals CandidaEsophagitis in an Immunocompetent Pregnant Woman

1993 ◽  
Vol 1 (3) ◽  
pp. 149-152 ◽  
Author(s):  
Jeffrey S. Greenspoon ◽  
Seth Kivnick
Keyword(s):  
Human Immunodeficiency Virus ◽  
Weight Loss ◽  
Candida Albicans ◽  
Gastrointestinal Endoscopy ◽  
Epigastric Pain ◽  
Upper Gastrointestinal Endoscopy ◽  
Second Trimester ◽  
Increased Risk ◽  
Immunodeficiency Virus ◽  
Upper Gastrointestinal

Background:Nausea and vomiting are common during the first half of pregnancy and usually require only supportive measures. When symptoms are progressive and weight loss occurs, treatable causes should be sought by means of upper gastrointestinal endoscopy. We report a case of an immunocompetent gravida with invasiveCandida albicansesophagitis.Case:The immunocompetent primigravida developed progressive nausea, vomiting, epigastric pain, and a 4.1 kg weight loss during the second trimester of pregnancy. Treatment with metoclopramide and cimetidine for presumed gastroesophageal reflux was not effective. The patient had normal T-cell CD4 and CD8 subsets and was human immunodeficiency virus (HIV) antibody negative. Upper gastrointestinal endoscopy revealedC. albicansesophagitis which was treated with oral nystatin. The esophagitis had resolved completely when reassessed postpartum. The use of histamine2blockers is associated with an increased risk for fungal esophagitis and may have been a contributing cause in this case.Conclusion:Pregnant patients with persistent nausea, vomiting, and weight loss should be evaluated by endoscopy for fungal esophagitis.

scholarly journals Acute Gastric Volvulus on Hiatal Hernia

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Abdessamad EL KAOUKABI ◽  
Mohamed MENFAA ◽  
Samir HASBI ◽  
Fouad SAKIT ◽  
Abdelkrim CHOHO
Keyword(s):  
Hiatal Hernia ◽  
Gastrointestinal Endoscopy ◽  
Epigastric Pain ◽  
Gastric Volvulus ◽  
Upper Gastrointestinal Endoscopy ◽  
Rare Entity ◽  
Midline Laparotomy ◽  
Acute Gastric Volvulus ◽  
Upper Abdominal ◽  
Upper Gastrointestinal

The gastric volvulus is defined as an abnormal rotation of all or part of the stomach around one of its axes, creating the conditions of an upper abdominal obstruction with gastric dilation and risk of strangulation. It is a rare entity that requires a surgical treatment, and its diagnosis is often delayed due to frequently aspecific symptoms. We will describe the observation of a 62 year old patient who presented to the emergency department for acute epigastric pain with dyspnea. The thoracoabdominal CT has demonstrated a stasis stomach on pyloric obstacle evoking a gastric torsion. An upper gastrointestinal endoscopy (EGD) and an upper gastrointestinal contrast made it possible to diagnose an acute gastric volvulus on hiatal hernia. A midline laparotomy was performed with detorsion of the stomach and repair of the hiatal hernia. The patient recovered gradually and was discharged on the sixth postoperative day. Three months after the operation, the patient remained asymptomatic.

One Patient, Two Lymphomas

2004 ◽  
Vol 128 (9) ◽  
pp. 1035-1038 ◽  
Author(s):  
Zuoqin Tang ◽  
Wen Jing ◽  
Neal Lindeman ◽  
Nancy Lee Harris ◽  
Judith A. Ferry
Keyword(s):  
Follicular Lymphoma ◽  
Lymphoid Tissue ◽  
Gastrointestinal Endoscopy ◽  
B Cell Lymphoma ◽  
Tissue Type ◽  
Gastric Disease ◽  
Upper Gastrointestinal Endoscopy ◽  
H Pylori ◽  
Upper Gastrointestinal

Abstract We report the case of a 73-year-old man who presented with a 2- to 3-month history of epigastric discomfort and guaiac-positive stool. An upper gastrointestinal endoscopy revealed a diffuse erythematous nodular mucosa and submucosal thickening in the stomach. Diffuse mucosal nodularity was also found in the second portion of the duodenum. A complete workup with histologic, immunohistochemical, and molecular studies revealed 2 distinct, apparently unrelated lymphomas, namely, a gastric marginal zone B-cell lymphoma (mucosa-associated lymphoid tissue type) in a background of Helicobacter pylori gastritis and a grade 1/3 duodenal follicular lymphoma. The patient was then treated with an H pylori eradication regimen. No therapy was given for his duodenal follicular lymphoma because his symptoms were thought to be due to the gastric disease and because the duodenal lesion was small. A 6-month follow-up with upper gastrointestinal endoscopy revealed only focal biopsy scarring in the stomach and an apparently normal duodenum. The follow-up biopsies revealed significant regression of his mucosa-associated lymphoid tissue lymphoma, but persistence of his duodenal follicular lymphoma. The combination of these 2 lymphomas in the same patient and the different clinical responses to antibiotic treatment make this case unique.

scholarly journals Helicobacter pylori Infection: Clinical, Endoscopic, and Histological Findings in Lebanese Pediatric Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
F. AL Kirdy ◽  
M. Rajab ◽  
N. El-Rifai
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Endoscopy ◽  
Pediatric Patients ◽  
Epigastric Pain ◽  
Demographic Data ◽  
Upper Gastrointestinal Endoscopy ◽  
Histopathological Findings ◽  
Increased Risk ◽  
H Pylori ◽  
Upper Gastrointestinal

Background. Helicobacter pylori (H. pylori) is a common and universally distributed bacterial infection. However, in children, active gastritis and ulcer are rarely seen. Objectives. The aims of this study were to establish the prevalence of H. pylori infection and to compare the clinical, endoscopic, and histopathological findings between infected and noninfected pediatric patients at Makassed General Hospital. Methods. Patients aged between 1 month and 17 years who underwent upper gastrointestinal endoscopy from January 2011 to January 2017 were included. The diagnosis of H. pylori was confirmed by a CLO test and/or its presence on biopsy specimens. Demographic data, clinical characteristics, endoscopic and histopathological findings, and gastritis score were recorded retrospectively. Results. During the study period, 651 children underwent upper gastrointestinal endoscopy. The main indication was abdominal pain (61%). The prevalence of H. pylori infection was 16.5%. The infection was most commonly seen among children aged between 6 and 10 years (43%). A large number of family members were associated with increased risk of infection (4.8±1.5 versus 5.2±1.8; p<0.05). Epigastric pain was more associated with H. pylori (61.3% versus 14.6% in noninfected patients; p<0.05). Nodular gastritis was commonly seen in infected patients (41.5% vs. 7.9%; p<0.05). Mild and moderate gastritis was seen more in infected versus noninfected patients (mild: 53.8% vs. 14%; moderate: 27.4% vs. 2.4%, respectively). Conclusion. Although epigastric pain was associated with H. pylori, other diagnoses should be considered since the infection are rarely symptomatic in children. Antral nodularity was associated with H. pylori infection; however, its absence does not preclude the diagnosis.

scholarly journals Upper gastrointestinal endoscopy; A study from a rural population of Sindh, Pakistan

2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Muhammad Kamran ◽  
Asher Fawwad ◽  
Syed Iftikhar Haider ◽  
Tahir Hussain ◽  
Jameel Ahmed
Keyword(s):  
Rural Population ◽  
Gastrointestinal Endoscopy ◽  
Epigastric Pain ◽  
Pathological Finding ◽  
Clinical Indication ◽  
Upper Gastrointestinal Endoscopy ◽  
Positive Finding ◽  
Primary Indication ◽  
Screening Endoscopy ◽  
Upper Gastrointestinal

Objective: To discuss common indications and findings on upper gastrointestinal endoscopy as well as to correlate these findings with alarm symptoms in the rural population of Gadap town, Sindh. Methods: This was a retrospective study on 1288 patients conducted in the medical ward of Fatima Hospital, Baqai Medical University. Patients’ demographics and other data related to the procedure were recovered from patients’ records. SPSS version 20 was used for statistical analysis. Results: Ratio of male and female patients was approximately 1:1. Majority of the patients were young, and most procedures were done as outpatients without the requirement of conscious sedation. Epigastric pain was the primary indication for upper GI endoscopy (62.6%). One third of the procedures performed did not report any pathological finding. Probability of a positive finding was more likely if a patient presented with dysphagia, heart-burn, hematemesis, vomiting, or for screening endoscopy (for varices). Patients who were diagnosed with esophageal candidiasis, esophageal varices or esophageal growth/ ulcer had reported one or more alarm symptoms in their history. Conclusions: Upper gastrointestinal endoscopy is a useful test to diagnose disorders of the esophagus, stomach and duodenum. However, it is an expensive procedure and therefore referring physicians should keep appropriate clinical indication and ethical considerations in mind before recommending such an investigation to their patients. doi: https://doi.org/10.12669/pjms.37.1.3297 How to cite this:Kamran M, Fawwad A, Haider SI, Hussain T, Ahmed J. Upper gastrointestinal endoscopy; A study from a rural population of Sindh, Pakistan. Pak J Med Sci. 2021;37(1):9-14. doi: https://doi.org/10.12669/pjms.37.1.3297 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Rare presentation of TB oesophagus: a case report

2018 ◽  
Vol 5 (9) ◽  
pp. 3180 ◽  
Author(s):  
Nagella Pradeep Kumar Reddy ◽  
S. Sabu Jeyasekharan ◽  
Nithila C. ◽  
A. Sai Kishore
Keyword(s):  
Case Report ◽  
Gastrointestinal Endoscopy ◽  
Tuberculosis Patient ◽  
Oesophageal Perforation ◽  
Upper Gastrointestinal Endoscopy ◽  
Rare Presentation ◽  
Upper Gi ◽  
Rare Case Report ◽  
Upper Gastrointestinal

This is a rare case report of Tb oesophagus presenting as upper GI bleeding. Patient was subjected to upper gastrointestinal endoscopy, which revealed an ulcerative growth in the mid oesophagus. Biopsy revealed oesophageal tuberculosis. Patient was managed conservatively with Anti-Tuberculosis Treatment (ATT). Follow up endoscopy after six months revealed resolution of the ulcer and patient was symptomatically better. In spite of the rare nature of the disease, it can be managed effectively with ATT to avoid complications (fistula, stricture, and oesophageal perforation), which might warrant surgery.

scholarly journals Successful Endoscopic Resection of an Early Carcinoma of the Duodenum

1999 ◽  
Vol 5 (4) ◽  
pp. 239-244 ◽  
Author(s):  
Tomoko Tada ◽  
Jyunya Arai ◽  
Akihiko Ohta ◽  
Kouitirou Satoh ◽  
Katuya Hattori ◽  
...  
Keyword(s):  
Biopsy Specimen ◽  
Gastrointestinal Endoscopy ◽  
Epigastric Pain ◽  
Early Carcinoma ◽  
Upper Gastrointestinal Endoscopy ◽  
Depth Of Invasion ◽  
Tubular Adenoma ◽  
Group Iii ◽  
Large Size ◽  
Upper Gastrointestinal

We describe a patient in whom an early carcinoma of the duodenum was able to be resected endoscopically. A 77-year-old man presented with epigastric pain. Upper gastrointestinal endoscopy revealed a mass in the duodenum, and the patient was admitted. A whitish nodular aggregated lesion, measuring 20 mm in diameter, was found in the second portion of the duodenum. Examination of a biopsy specimen showed a Group III tubular adenoma. Endoscopic ultrasonography showed that the lesion was confined to the mucosa. The large size of the lesion suggested the possibility of malignancy. Endoscopic mucosal resection was therefore performed. Histopathologically, the diagnosis was carcinoma in adenoma. The depth of invasion was mucosal. We conclude that endoscopic muosal resection can be used to treat mucosal lesions arising in the duodenum.

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