scholarly journals Hyperbolic relation between beta-cell function and insulin sensitivity for type 2 diabetes mellitus, malaria, influenza, Helicobacter pylori, Chlamydia pneumoniae,and hepatitis C virus infection-induced inflammation/oxidative stress and temporary insulin resistance in Central Africans*

2017 ◽  
Vol 47 ◽  
pp. 1834-1841 ◽  
Author(s):  
Jean Bosco Kasiam Lasi ON’KIN ◽  
Benjamin LONGO-MBENZA ◽  
Venant TCHOKONTE-NANA ◽  
Augustin Nge OKWE ◽  
Nelly Kangola KABANGU
2007 ◽  
Vol 4 (2_suppl) ◽  
pp. S7-S11 ◽  
Author(s):  
Michel P Hermans

Before a patient develops overt type 2 diabetes mellitus, there is typically a prolonged period of patho-physiological change. In the common form of type 2 diabetes mellitus, there are years of insulin resistance, initially compensated by increased beta cell function, then impaired glucose tolerance develops, and finally type 2 diabetes. We know from studies such as the United Kingdom Prospective Diabetes Study (UKPDS) and the Belfast study that loss of beta cell function and insulin resistance are usually relentless.1, 2 Thus, therapy to reduce blood glucose has to be gradually increased with time for patients with diabetes. What is less well known is that every person has a different slope for beta cell function loss which intersects with insulin resistance.


2008 ◽  
Vol 32 (4) ◽  
pp. 310
Author(s):  
Kristy Wittmeier ◽  
Samatha Carey ◽  
Joanne Hamilton ◽  
Andrea Macintosh ◽  
Elizabeth Sellers ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document