A micro-morphometric study on the common bile duct and major duodenal papilla of the domestic swine

2021 ◽  
Vol 25 (2) ◽  
pp. 48-54
Author(s):  
V. A. Lazarenko ◽  
Y. V. Kanishchev ◽  
P. M. Nazarenko ◽  
D. P. Nazarenko ◽  
T. A. Samgina ◽  
...  

Objective. The radical elimination of extrahepatic biliary tract pathology in choledocholithiasis and acute biliary pancreatitis (ABP) reduces the risk of infection and eliminates the source of endogenous intoxication; so, the search of safe and effective techniques for endoscopic papillosphincterotomy (EPT) is important.Purpose: to assess outcomes of laser-assisted endoscopic papillosphincterotomy.Material and methods. 288 patients with “wedged” (n = 111) and “valve” (n = 177) choledocholithiasis and acute biliary pancreatitis were divided into two groups depending on EPT technique: in the control group, a papillotome with electrocoagulation cord was used (n = 195); in the main group, laser scalpel was used (n = 93).Results. 87 patients with “wedged” choledocholithiasis were treated with EPT and an end electrode on the wedged stone. 16 patients out of them had mild bleeding which was stopped by irrigation with epinephrine solution (1 : 10 000) followed by the targeted coagulation. The average surgical time was 38 ± 16 min. In 24 patients with rigid and edematous medial wall of the duodenum due to acute biliary pancreatitis, the proposed device plus laser technique for papillosphincterotomy were used (patent of the Russian Federation No. 2614891). There was no bleeding, the average surgical time was 24 ± 12 min. In “valve” choledocholithiasis, laparoscopic cholecystectomy (LCE) was performed; calculi from the common bile duct were removed. In 108 patients during LCE, EPT was made via an antegrade catheter. In 69 patients with anatomical and physiological obstacles caused by the major duodenal papilla, we performed LCE and EPT with laser light via an antegrade guide light made of fluoroplastics (patent of the Russian Federation No. 41594). Concrements from the common bile duct were removed with the Dormia basket.Conclusions. Laser light causes less damage, reliably provides hemostasis along the incision line on the anterior wall of the major duodenal papilla; in addition, a wedged calculus in “wedged” choledocholithiasis and a fluoroplastic light guide in “valve” choledocholithiasis reliably protect the posterior wall of the major duodenal papilla from laser light damage. Laser techniques used in EPT make the treatment of choledocholithiasis in patients with ABP having anatomical and physiological problems due to the major duodenal papilla safe and effective.


2021 ◽  
pp. 5-17
Author(s):  
Vladimir Alexandrovich Ivanov ◽  
Roman Nikolaevich Malushenko ◽  
Alexander Evgenievich Denisov ◽  
Elena Nikolaevna Kondrashenko

Mechanical jaundice is a clinical syndrome that develops due to the bile flow impairment along the bile ducts to the duodenum, remains one of the urgent problems of medicine. Of great importance among the causes of mechanical jaundice are diseases of the common bile duct and the major duodenal papilla, the diagnosis of which to this day remains a rather difficult task. The use of MRCP, ERСP, endo-ultrasonography and other highly informative bile tract imaging methods, despite great diagnostic capabilities, is associated with a number of limitations. In this regard, an important place, especially in the primary examination of patients, is occupied by transabdominal ultrasound, the advantages of which are non-invasiveness, portability, accessibility, safety, the possibility of multiple reiteration. A review of the literature presents domestic and foreign data of researchers regarding the possibility of ultrasonography in diagnostics of the common bile duct pathology and the pathology of the major duodenal papilla that are complicated by mechanical jaundice, as well as the greatest difficulties in diagnosing this pathology.


2016 ◽  
Vol 21 (5) ◽  
pp. 244-249
Author(s):  
Yury S. Vinnik ◽  
E. V Serova ◽  
D. A Chernykh ◽  
A. V Kovalev ◽  
D. V Stratovich ◽  
...  

In the structure of malignant tumors, accompanied by obstructive jaundice, there are most occurred such as the lesion of the pancreas (47%), bile duct cancer (20%) also papillary carcinoma (MDP) and gall bladder cancer (about 15%). In the case of inoperable tumor, in elderly and senile patients with severe concomitant somatic pathology, there are indicated palliative interventions as follows: percutaneous transhepatic external or external-internal drainage of the biliary tract with possible subsequent percutaneous transhepatic stenting of the common bile duct. Under our observation there was a patient of 75 years with verified major duodenal papilla cancer, complicated by obstructive jaundice, to whom as the first step there was performed percutaneous transhepatic external-internal drainage of the biliary tract, and as the second one - percutaneous transhepatic stenting of the common bile duct.


1981 ◽  
Vol 62 (5) ◽  
pp. 41-42
Author(s):  
O. S. Kochnev ◽  
V. N. Biryaltsev

Determination of the state of the biliary tract and the terminal part of the common bile duct is one of the most difficult issues of intraoperative diagnosis in complicated cholecystitis. Currently, none of the surgeons doubts the need for intraoperative cholangiography and its value. It is she who allows to identify in many patients the presence of calculi in the biliary tract, to determine the degree of expansion of the common bile duct and bile hypertension, the state of the terminal part of the common bile duct. However, the analysis of radiographs performed during 170 surgical interventions for various degrees of stenosis of the large duodenal papilla showed that even this most reliable method of intraoperative diagnosis has a significant drawback.


2019 ◽  
pp. 26-29
Author(s):  
I. N. Mamontov

Abstract. Aim: to determine the factors influencing on bacteribilia in patients with benign obstruction of the extrahepatic biliary tract (BOEBT). Materials and Methods. A study of 30 cases of BOEBT with bacteriologic bile assessment was performed. A comparison of the incidence of different factors in patients with or without bacteriobilia was done. Results. Positive bile culture was in 22 (73.3%) patients. The most common were E. coli and Klebsiella (68.2%). There was no difference (p<0.05) in sex, age, bilirubin level, gallbladder condition, common bile duct size, major duodenal papilla (MDP) size, common bile duct stones, sludge, Mirizzi syndrome, impacted stone in MDP. Significant differences were found in number of common bile duct stones: 1-2 stones (p<0,001) and multiple stones (p<0,05). Conclusions. Risk factors for bacteriobilia is 1-2 stones in the common bile duct (p<0,001). Multiple stones (≥3) are not associated with bacteriobilia (p<0,05).


2021 ◽  
pp. 104063872110171
Author(s):  
Megan E. Schreeg ◽  
Sybille A. Miller ◽  
John M. Cullen

Choledochal cysts, congenital segmental dilations of the common bile duct, have been reported in few cats, and histologic characterization is lacking. A 20-mo-old spayed female domestic shorthair cat was presented because of vomiting and weight loss. There was progressive elevation of liver enzyme activity (ALT > ALP, GGT) and hyperbilirubinemia. Diagnostic imaging identified focal cystic dilation of the common bile duct, dilation and tortuosity of adjacent hepatic ducts, and a prominent duodenal papilla. A choledochal cyst was suspected, and the animal was euthanized. On postmortem examination, there was a 2-cm, firm, thickened, cystic dilation of the common bile duct, patent with adjacent ducts. Histologically, the cyst wall was expanded by fibroblasts, collagen, and lymphoplasmacytic inflammation. Adjacent bile ducts were markedly dilated and tortuous, with lymphoplasmacytic inflammation and papillary mucosal hyperplasia that extended to the major duodenal papilla. There was chronic neutrophilic cholangitis, suggesting bacterial infection and/or disturbed bile drainage, extrahepatic obstruction, and lymphoplasmacytic pancreatitis with ductular metaplasia. Prominent lymphoid follicles within biliary ducts and duodenum suggested chronic antigenic stimulation. Choledochal cysts can be associated with chronic neutrophilic cholangitis, extrahepatic obstruction, choledochitis, duodenal papillitis, and pancreatitis, and should be a differential for increased hepatic enzymes and hyperbilirubinemia in young cats.


2007 ◽  
Vol 12 (6) ◽  
pp. 1146-1148 ◽  
Author(s):  
Shuichiro Uchiyama ◽  
Kazuo Chijiiwa ◽  
Naoya Imamura ◽  
Masahide Hiyoshi ◽  
Jiro Ohuchida ◽  
...  

2020 ◽  
pp. 21-26
Author(s):  
I. М. Mamontov

Abstract. The aim of the research was to studying histological and some morphomethrics feathers of the liver and related with them lethality during experimental complete and partial obstruction of the extrahepatic bile ducts (COEHBD and POEHBD). Materials and methods. The experiment was included 83 rats that were sacrificed on the 3rd, 7th, 14th, 21st, 28th and 35th days. COEHBD was modeled by ligation and transaction of the common bile duct, POEHBD was modeled by ligation of the common bile duct with a needle of a given diameter. Histological analyses of the liver was performed together with morphometric study. Results. The death of rats occurs during the first 3 days of the experiment and after 14 days, with a predominance of mortality on 14-35 days compared to the period up to 14 days (p<0.05). Death after 14 days of the experiment occurs in the model of complete cholestasis. From the all investigated morphometric measures such as the hepatocytes volume density (HVD), liver volume (LV), total hepatocytes volume (THV), the last one is the most accurately reflects the compensatory capabilities of the liver in conditions of complete and partial cholestasis and can serve as a criteria for predicting of the fatal outcome. Conclusion. The THV most accurately reflects the compensatory capabilities of the liver in experimental COEHBD and POEHBD and can serve as a criterion for predicting a fatal outcome.


2021 ◽  
Vol 7 (1) ◽  
pp. 205511692098439
Author(s):  
Francesca Venier ◽  
Krizia Compagnone ◽  
Annette Kerins ◽  
Chantal Rosa

Case summary An 11-year-old neutered female domestic shorthair cat presented to our hospital with a 5-day history of vomiting, lethargy, anorexia and hyperbilirubinaemia, despite intravenous fluid therapy, gastroprotectants and antibiotic treatment. An abdominal ultrasound revealed a markedly distended common bile duct (diameter 6.2 mm). The cystic duct and intrahepatic bile ducts were also dilated. A linear structure formed by two parallel hyperechoic lines was identified in the common bile duct and could be traced to the duodenal papilla. The cat underwent laparotomy for surgical decompression of the biliary tree. A tubular, brown-coloured structure was retrieved from the common bile duct. Histological examination was consistent with a degenerate helminth. The cat recovered uneventfully from the surgery and its demeanour and appetite improved rapidly over the following days. Liver and gallbladder wall histopathology was consistent with bacterial cholangitis and cholecystitis. Escherichia coli was cultured from both bile and liver parenchyma. Relevance and novel information To our knowledge, this is the first reported case of extrahepatic biliary duct obstruction caused by a helminth in a cat in the UK. We hypothesised that the obstruction had been caused by the aberrant migration of an intestinal nematode that became lodged in the duodenal papilla. Ultrasound allowed prompt diagnosis and guided the treatment decision.


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