scholarly journals A case of noninvasive ductal carcinoma with focal microinvasion in the duct wall of the male breast with bloody nipple discharge.

2002 ◽  
Vol 63 (3) ◽  
pp. 575-578
Author(s):  
Noriaki WADA ◽  
Masato FUJISAKI ◽  
Takayuki TAKAHASHI ◽  
Shinobu HIRAHATA ◽  
Dai MAEDA ◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Nipple Discharge ◽  
Male Breast ◽  
Bloody Nipple Discharge ◽  
Duct Wall ◽  
Noninvasive Ductal Carcinoma

scholarly journals A spontaneous unveiling of bilateral DCIS in an elderly male

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Tessa Meyer ◽  
Patrick Borgen ◽  
Kristen Rojas
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Ductal Carcinoma ◽  
Nipple Discharge ◽  
Incidence Rates ◽  
Male Breast ◽  
Elderly Male ◽  
Brca Mutations ◽  
Cancer Risk Factors ◽  
Bloody Nipple Discharge

Abstract The rarity of male breast cancer continues to limit its study despite increasing incidence rates, particularly within the past decade [Speirs V, Shaaban AM. The rising incidence of male breast cancer. Breast Cancer Res Treat 2009;115:429–30]. Although this trend appears to be substantially documented, male patients with breast cancer have been and continue to be excluded from landmark breast cancer trials. Currently, there are no standardized breast cancer screening protocols in place for men, including those with pathogenic BRCA mutations. As a result, men with breast cancer typically present at a later stage, and on average, 8–10 years later than females [Ruddy KJ, Winer EP. Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. Ann Oncol 2013;24:1434–43]. As the incidence of disease continues to rise, the need for algorithmic standardization with regards to screening, diagnosing, treating and managing male breast cancer has become imperative. We report the case of a 71-year-old male who presented with spontaneous bloody nipple discharge and was found to have bilateral ductal carcinoma in situ.

Cystic Encapsulated Papillary Carcinoma in the Male Breast: An Unusual Feature With a Diagnostic Challenge

2021 ◽  
pp. 106689692110187
Author(s):  
Rongying Li ◽  
Karan Saluja ◽  
Brenda Mai ◽  
Michael Covinsky ◽  
Hongxia Sun
Keyword(s):  
Papillary Carcinoma ◽  
Cyst Wall ◽  
Correct Diagnosis ◽  
Nipple Discharge ◽  
Left Breast ◽  
Male Breast ◽  
Unusual Feature ◽  
Breast Mass ◽  
Repeat Biopsy ◽  
Bloody Nipple Discharge

Papillary carcinoma in the male breast is uncommon. Here, we report a case of a large encapsulated papillary carcinoma (EPC) in a 62-year-old male. The patient presented with a left breast mass of 1-year duration and bloody nipple discharge for several days. Mammography and breast ultrasonography showed a large left breast mass. The initial biopsy demonstrated fat necrosis with acute and chronic inflammation only. Due to clinical suspicion, a repeat biopsy was performed and revealed scant fragments of papillary carcinoma in a background of inflammation. The patient underwent left total mastectomy. Grossly, the breast contained a 9.0 cm entirely cystic lesion lined by a hemorrhagic thick fibrotic wall. No solid area was identified in the cyst. The entire cyst wall was examined under microscopy; only a few sections with papillary carcinoma were identified. The lesion was confined to the cyst wall; so, a diagnosis of EPC was made. Compared to the previously reported EPC cases of male breast, the lesion of this case was unusually cystic, which making the diagnosis challenging. Therefore, awareness of this unusual feature, repeat biopsy when the pathology result is discordant, and extensive sampling of the lesion are essential for making the correct diagnosis and guiding patient management.

scholarly journals A CASE OF NONIVASIVE CARCINOMA OF THE MALE BREAST WITH BLOODY NIPPLE DISCHARGE

1998 ◽  
Vol 59 (10) ◽  
pp. 2514-2517
Author(s):  
Teruhisa SAKURAI ◽  
Takaomi SUZUMA ◽  
Shinichiro MIYOSHI ◽  
Hirokazu TANINO ◽  
Shinii MAEBEYA ◽  
...  
Keyword(s):  
Nipple Discharge ◽  
Male Breast ◽  
Bloody Nipple Discharge

Unilateral nipple discharge in a man without a palpable mass diagnosed as breast cancer

2020 ◽  
Vol 13 (11) ◽  
pp. e236223
Author(s):  
Karan N Ramakrishna ◽  
Justin Durland ◽  
Christopher Ramos ◽  
Amit Singh Dhamoon
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Ductal Carcinoma ◽  
Early Recognition ◽  
Nipple Discharge ◽  
Care Physician ◽  
Male Breast ◽  
Laboratory Findings ◽  
Palpable Mass ◽  
History Of

A 69-year-old man without a family history of breast cancer presented to his primary care physician with a 1-year history of clear, unilateral nipple discharge (ND) without an associated palpable breast mass. His laboratory findings were significant for hyperprolactinaemia at 28 ng/mL. Diagnostic work up including mammography, ultrasound and core needle biopsy ultimately revealed a ductal carcinoma in situ and a rare papillary variant of invasive ductal carcinoma. The patient was referred to a multidisciplinary oncology team and underwent a right total mastectomy followed by adjuvant hormonal therapy. The patient made a good postoperative recovery and remains without evidence of recurrence 6 months from surgery. Male breast cancer is rare, but its incidence is increasing. Male breast cancer presenting as ND without a palpable mass is uncommon. Early recognition of breast symptoms in men can lead to earlier diagnoses and improved outcomes.

Breast cancer in male veterans: A retrospective chart review.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e12531-e12531
Author(s):  
Anita Aggarwal ◽  
Min-Ling L Liu ◽  
Nihar Kiritkumar Patel ◽  
Rebecca Evangelista ◽  
Steven Krasnow
Keyword(s):  
Breast Cancer ◽  
Ductal Carcinoma ◽  
Nipple Discharge ◽  
Agent Orange ◽  
Clinicopathologic Characteristics ◽  
Palpable Mass ◽  
Bloody Nipple Discharge ◽  
Male Veterans ◽  
Male Patients

e12531 Background: Male breast cancer (BCA) is rare and makes up < 1% of all of breast cancer cases. Treatment is mainly based on what is known from female BCA and survival is similar between genders. Objectives: To investigate the clinicopathologic characteristics of BCA and overall survival in male veterans. Methods: Medical records of male patients diagnosed with breast cancer at the Veterans Affairs Medical Centers of Washington DC, Baltimore and Martinsburg from 1992-2012 were reviewed after Institutional Review Board approval. Results: From 1995-2012, 51 male patients with BCA were identified from cancer registry. 29/51(57%) were African American (AA), 41% Caucasian (WM), and 2% other race. Median age was 70 years (44-86years). Palpable mass was presenting symptom in 41/51(80%) and 8(16%) had gynecomastia or bloody nipple discharge. Family history of breast cancer was positive in 11 patients without mention of BRCA genes except pt #24 who was BRCA2+. 3 patients were exposed to Agent Orange. ER/PR was positive in 36(71%), ER+/PR- in 1(2%), ER+/PR+/HER2+ in 2(4%), ER-/PR-/HER- in 2(4%). 41% & 57% had right and left BCA, respectively. 40 (80%) underwent mastectomy. 18(36%) had lymph node involvement (1-13 LN). 90% had invasive ductal carcinoma (IDC), 8% DCIS, and 2% sarcoma. Cancer in 26% was stage I, 38% stage II, 18% stage III and 8% stage IV. 12(24%) received combination chemotherapy. 33(66%) were given tamoxifen. 4(8%) patients had relapsed/recurrent disease in 1-5 years of their diagnosis and died within 2-12 years after the relapse. At median follow up of 174m (4m-19years), 28(56%) patients died (cause of death not known in all), 21(42%) alive and 3(6%) lost to follow up. Conclusions: Median age at diagnosis of BCA seems to be higher in males (70 years) as compared to historical female age (60 years). IDC is the main pathology and 73% tumors were ER +. Survival rate is approximately 40% at >10years of follow up. Survival by stage revealed no difference.

Synchronous bilateral noninvasive ductal carcinoma of the male breast: A case report

Breast Cancer ◽  
2003 ◽  
Vol 10 (2) ◽  
pp. 163-166 ◽  
Author(s):  
Kenzo Okada ◽  
Shinsuke Kajiwara ◽  
Hitoshi Tanaka ◽  
Goi Sakamoto
Keyword(s):  
Case Report ◽  
Ductal Carcinoma ◽  
Male Breast ◽  
Noninvasive Ductal Carcinoma

scholarly journals Noninvasive ductal carcinoma of the male breast with marked apocrine metaplasia.

1994 ◽  
Vol 33 (4) ◽  
pp. 691-696 ◽  
Author(s):  
Mituyuki KINJO ◽  
Keiko TAIRA ◽  
Akira TERUYA ◽  
Cyorei YOHENA ◽  
Haruo KINA ◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Male Breast ◽  
Apocrine Metaplasia ◽  
Noninvasive Ductal Carcinoma

scholarly journals Ductal Carcinoma In situ of the Male Breast

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 288-290 ◽  
Author(s):  
Melissa Brents ◽  
John Hancock
Keyword(s):  
Breast Cancer ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Histological Grade ◽  
Nipple Discharge ◽  
Left Breast ◽  
Male Breast ◽  
High Grade

Background: Ductal carcinoma in situ of the male breast is an unusual lesion and most often associated with invasive carcinoma. On rare occasions when the in situ component is present in pure form, histological grade is almost always low to intermediate. Imaging for these patients is difficult as gynecomastia is often present and can mask underlying calcifications or carcinoma. Case Report: We report a case of pure high-grade ductal carcinoma in situ of the male breast in a patient with clear nipple discharge. Breast mammography showed bilateral gynecomastia and benign calcifications. Subsequent breast ultrasound showed dilated ducts of the left breast, and a left breast ductogram showed filling defects suggestive of a papilloma. Excisional biopsy and subsequent mastectomy were consistent with high-grade ductal carcinoma in situ. Conclusion: Male breast cancer is uncommon and, although there is increasing awareness, it is less studied compared to female breast cancer. With a clinical history of nipple discharge of any kind, further evaluation with imaging should be considered. In males with gynecomastia, it is important to remember that ductal carcinoma in situ, even of high grade, is difficult to detect on mammography and may not be associated with suspicious calcifications.

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