Genomics and Population Health

2013 ◽  
pp. 240-248
Author(s):  
Chan Chee Khoon
Keyword(s):  
Adverse Effects ◽  
Knowledge Base ◽  
Population Health ◽  
State Of Health ◽  
General State ◽  
The Right ◽  
The Way

Imagine being able to find out how a drug will affect you before you take it... receiving a medication that is specifically tailored to treat your disease, while minimizing your risk of developing adverse effects. Although a person’s environment, diet, and general state of health can all influence how he or she responds to medicines, another important factor is genes. Pharmacogenetics is the study of how your genes affect the way your body responds to a medicine. Pharmacogenetics helps to determine what the right medicine is for you, based on your own genes.1 The Pharmacogenetics and Pharmacogenomics Knowledge Base http://www.pharmgkb.org/resources/education/phar-genetics.jsp.

Genomics and Population Health

2011 ◽  
pp. 15-23
Author(s):  
Chan Chee Khoon
Keyword(s):  
Adverse Effects ◽  
Knowledge Base ◽  
Population Health ◽  
State Of Health ◽  
General State ◽  
The Right ◽  
The Way

Imagine being able to find out how a drug will affect you before you take it... receiving a medication that is specifically tailored to treat your disease, while minimizing your risk of developing adverse effects. Although a person‘s environment, diet, and general state of health can all influence how he or she responds to medicines, another important factor is genes. Pharmacogenetics is the study of how your genes affect the way your body responds to a medicine. Pharmacogenetics helps to determine what the right medicine is for you, based on your own genes.1 The Pharmacogenetics and Pharmacogenomics Knowledge Base http://www.pharmgkb.org/resources/education/phar-genetics.jsp.

scholarly journals Application of atomic force microscopy in biology and medicine

2021 ◽  
Vol 2058 (1) ◽  
pp. 012029
Author(s):  
V G Nikitaev ◽  
A N Pronichev ◽  
T K Markov ◽  
N Esaulov
Keyword(s):  
Atomic Force Microscopy ◽  
Atomic Force Microscope ◽  
Knowledge Base ◽  
Human Body ◽  
State Of Health ◽  
General State ◽  
Force Microscopy ◽  
Atomic Force

Abstract This article presents the main areas of application of atomic force microscopy in biology and medicine, describes the principle of an atomic force microscope and the main modes of its operation. The works and results of the leading laboratories in the stated topic are considered. There are a number of proposals for generalizing the considered results into a unified knowledge base on diseases and the general state of health of the human body.

CONCEPT OF PATIENT’S ADVANCE EXPRESSED WILL

2019 ◽  
pp. 282
Author(s):  
Dagnija Volodjko
Keyword(s):  
Self Determination ◽  
Best Interests ◽  
Right To Know ◽  
State Of Health ◽  
The Right To Know ◽  
The Right ◽  
Medical Examinations ◽  
Insight Into ◽  
The Way

The patient may be found in a situation where he can no longer make decisions because of an accident or illness. It is considered that the decision on treatment admit in the best interests of the patient, but without certain written instructions it is almost impossible. The patient's advance expressed will is the way in which any person can express the exact wishes of treatment for particular situations at a time when patient can’t made the decision. There is a need to respect to the principle of self-determination, where the patient has the right to know all the information about his state of health and he can determine in what situations he agrees or prohibits certain medical examinations, treatments or interventions. In Latvia, the idea of the patient's advance expressed will has been not many research and not implemented, so the work gives an insight into the concept and content of the patient's advance expressed will.

The adaptation of design thinking in auditing

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Linda MEIJER-WASSENAAR ◽  
Diny VAN EST
Keyword(s):  
The Netherlands ◽  
Design Thinking ◽  
Public Organizations ◽  
Design Framework ◽  
The Right ◽  
The Way

How can a supreme audit institution (SAI) use design thinking in auditing? SAIs audit the way taxpayers’ money is collected and spent. Adding design thinking to their activities is not to be taken lightly. SAIs independently check whether public organizations have done the right things in the right way, but the organizations might not be willing to act upon a SAI’s recommendations. Can you imagine the role of design in audits? In this paper we share our experiences of some design approaches in the work of one SAI: the Netherlands Court of Audit (NCA). Design thinking needs to be adapted (Dorst, 2015a) before it can be used by SAIs such as the NCA in order to reflect their independent, autonomous status. To dive deeper into design thinking, Buchanan’s design framework (2015) and different ways of reasoning (Dorst, 2015b) are used to explore how design thinking can be adapted for audits.

Memories for the Return? Remembering the Nakba by the First Generation of Palestinian Refugees in Syria

2017 ◽  
Vol 16 (2) ◽  
pp. 177-192 ◽  
Author(s):  
Anaheed Al-Hardan
Keyword(s):  
First Generation ◽  
Palestinian Refugees ◽  
Oslo Accords ◽  
Right Of Return ◽  
Palestinian Refugee ◽  
Temporal And Spatial ◽  
The Right ◽  
Political Realities ◽  
The Way

The 1948 Nakba has, in light of the 1993 Oslo Accords and Palestinian refugee activists' mobilisation around the right of return, taken on a new-found centrality and importance in Palestinian refugee communities. Closely-related to this, members of the ‘Generation of Palestine’, the only individuals who can recollect Nakba memories, have come to be seen as the guardians of memories that are eventually to reclaim the homeland. These historical, social and political realities are deeply rooted in the ways in which the few remaining members of the generation of Palestine recollect 1948. Moreover, as members of communities that were destroyed in Palestine, and whose common and temporal and spatial frameworks were non-linearly constituted anew in Syria, one of the multiples meanings of the Nakba today can be found in the way the refugee communities perceive and define this generation.

Comparative Views on the Right to Vote in International Law

2018 ◽  
Author(s):  
Shai Dothan
Keyword(s):  
Human Rights ◽  
International Law ◽  
National Courts ◽  
European Court ◽  
Right To Vote ◽  
The Right ◽  
Democratic Elections ◽  
The Way

There is a consensus about the existence of an international right to vote in democratic elections. Yet states disagree about the limits of this right when it comes to the case of prisoners’ disenfranchisement. Some states allow all prisoners to vote, some disenfranchise all prisoners, and others allow only some prisoners to vote. This chapter argues that national courts view the international right to vote in three fundamentally different ways: some view it as an inalienable right that cannot be taken away, some view it merely as a privilege that doesn’t belong to the citizens, and others view it as a revocable right that can be taken away under certain conditions. The differences in the way states conceive the right to vote imply that attempts by the European Court of Human Rights to follow the policies of the majority of European states by using the Emerging Consensus doctrine are problematic.

Normative Concepts

2017 ◽  
Author(s):  
Matti Eklund
Keyword(s):  
Positive Answer ◽  
Thick Concepts ◽  
Normative Concepts ◽  
The Right ◽  
The Way

What is it for a concept to be normative? Some possible answers are explored and rejected, among them that a concept is normative if it ascribes a normative property. The positive answer defended is that a concept is normative if it is in the right way associated with a normative use. Among issues discussed along the way are the nature of analyticity, and there being a notion of analyticity—what I call semantic analyticity—such that a statement can be analytic in this sense while failing to be true. Considerations regarding thick concepts and slurs are brought to bear on the issues that come up.

The Inviolability of Diplomatic Agents in the Context of Employment

2017 ◽  
Author(s):  
Lisa Rodgers
Keyword(s):  
Human Rights ◽  
Fair Trial ◽  
European Convention ◽  
Employment Contracts ◽  
Domestic Servants ◽  
Recent Developments ◽  
Diplomatic Immunity ◽  
The Right ◽  
The Way

‘Ordinary’ employment contracts—including those of domestic servants—have been deemed to attract diplomatic immunity because they fall within the scope of diplomatic functions. This chapter highlights the potential for conflict between these forms of immunity and the rights of the employees, and reflects on cases in which personal servants of diplomatic agents have challenged both the existence of immunity and the scope of its application. The chapter examines claims that the exercise of diplomatic immunity might violate the right to a fair trial under Article 6 of the European Convention on Human Rights and the way in which courts have dealt with these issues. The chapter analyses diplomats’ own employment claims and notes that they are usually blocked by the assertion of immunity, but also reflects on more recent developments in which claims had been considered which were incidental to diplomatic employment (eg Nigeria v Ogbonna [2012]).

scholarly journals A Sensibilist Explanation of Imaginative Resistance

2021 ◽  
pp. 1-16
Author(s):  
Nils Franzén
Keyword(s):  
Actual World ◽  
David Hume ◽  
Recent Discussion ◽  
Personal Taste ◽  
Predicates Of Personal Taste ◽  
Imaginative Resistance ◽  
The World ◽  
The Right ◽  
Evaluative Terms ◽  
The Way

Abstract This article discusses why it is the case that we refuse to accept strange evaluative claims as being true in fictions, even though we are happy to go along with other types of absurdities in such contexts. For instance, we would refuse to accept the following statement as true, even in the context of a fiction: (i) In killing her baby, Giselda did the right thing; after all, it was a girl. This article offers a sensibilist diagnosis of this puzzle, inspired by an observation first made by David Hume. According to sensibilism, the way we feel about things settles their evaluative properties. Thus, when confronted with a fictional scenario where the configuration of non-evaluative facts and properties is relevantly similar to the actual world, we refuse to go along with evaluative properties being instantiated according to a different pattern. It is the attitudes we hold in the actual world that fix the extension of evaluative terms, even in nonactual worlds. When engaging with a fiction, we (to some extent) leave our beliefs about what the world is like behind, while taking our emotional attitudes with us into the fiction. To substantiate this diagnosis, this paper outlines a sensibilist semantics for evaluative terms based on recent discussion regarding predicates of personal taste, and explains how, together with standard assumptions about the nature of fictional discourse, it makes the relevant predictions with respect to engagement with fictions.

scholarly journals Psychosocial Burden and Strains of Pedagogues—Using the Job Demands-Resources Theory to Predict Burnout, Job Satisfaction, General State of Health, and Life Satisfaction

2021 ◽  
Vol 18 (15) ◽  
pp. 7921
Author(s):  
Marie Drüge ◽  
Sandra Schladitz ◽  
Markus Antonius Wirtz ◽  
Karin Schleider
Keyword(s):  
Job Satisfaction ◽  
Life Satisfaction ◽  
Prediction Model ◽  
Social Workers ◽  
Job Demands ◽  
State Of Health ◽  
General State ◽  
Psychosocial Burden ◽  
Role Conflicts ◽  
Copenhagen Psychosocial Questionnaire

The current study examines the Job Demands-Resources theory among pedagogical professionals. A total of 466 pedagogues (n = 227 teachers; n = 239 social workers) completed the Copenhagen Psychosocial Questionnaire online. After testing the questionnaire structure using confirmatory factor analysis, a JD-R-based prediction model to predict effects of strains on the outcome constructs of burnout, job satisfaction, general state of health, and life satisfaction was estimated. The results confirm the questionnaire structure (RMSEA= 0.038; CFI = 0.94) as well as the fit of the prediction model (RMSEA = 0.039; CFI = 0.93). The outcome constructs could be predicted by emotional demands, work–privacy conflict, role conflicts, influence at work, scope for decision making, and opportunities for development (0.41 ≤ R² ≤ 0.57). Especially for life satisfaction, a moderator analysis proved the differences between teachers and social workers in the structure of the prediction model. For teachers, quantitative demands and work–privacy conflict are predictive, and for social workers, role conflicts and burnout are predictive. The study offers starting points for job-related measures of prevention and intervention.

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