Diabetic Data Warehouses

Author(s):  
Joseph L. Breault

The National Academy of Sciences convened in 1995 for a conference on massive data sets. The presentation on health care noted that “massive applies in several dimensions . . . the data themselves are massive, both in terms of the number of observations and also in terms of the variables . . . there are tens of thousands of indicator variables coded for each patient” (Goodall, 1995, paragraph 18). We multiply this by the number of patients in the United States, which is hundreds of millions.

2019 ◽  
Vol 25 (11) ◽  
pp. 1773-1779 ◽  
Author(s):  
David A Schwartz ◽  
Ignacio Tagarro ◽  
Mary Carmen Díez ◽  
William J Sandborn

Abstract Background Fistulas may arise as a relevant complication of Crohn’s disease (CD). Despite their clinical significance and the substantial burden imposed on patients, limited data are available on the epidemiology of fistulizing CD in the United States. Methods A systematic literature review was conducted to identify data published between 1970 and 2017 on the epidemiology of fistulas in patients with CD, with the aim to estimate the number of prevalent cases in the United States. Retrieved titles and abstracts were screened by 2 independent researchers for inclusion criteria (US population-based studies reporting data on the epidemiology of fistulizing CD). To validate the literature-based estimate, data from a US claims database (Truven Health MarketScan database) were analyzed. This database has broad geographic coverage, with health care data for >60 million patients during the period of the analysis. Results The literature search retrieved 7 articles for full-text review, and only 1 met the criteria for inclusion. This study described the cumulative incidence of fistulas in a CD population from Minnesota over 20 years. From the reported data, the estimated number of prevalent cases with fistulizing CD in the United States was ~76,600 in 2017 (~52,900 anal, ~7400 rectovaginal, ~2300 enterocutaneous, and ~14,100 internal). Analysis from the US health care database resulted in an estimated number of ~75,700 patients, confirming the robustness of the original estimate from the literature. Conclusions Based on 2 separate analyses, the estimated number of patients with fistulizing CD in the United States is ~77,000 patients.


2004 ◽  
Vol 95 (2) ◽  
pp. 487-493
Author(s):  
Xiaofang Gao

Hedge is defined as the expression of provisionalness and possibility that makes scientific messages tentative, vague, and imprecise, thereby reducing the force of claims scientists make. Linguistic study of hedges began in the early 1970s in generative semantics. Since then, the focus has shifted from seeking linguistic properties in spoken discourse to analyzing its pragmatic functions in written contextual communication. The purpose of this paper was to analyze hedges in Chinese and English scientific articles from the perspective of contrastive pragmatics. Based on a contextual analysis of 5 Chinese and 5 English scientific articles, selected randomly, from two journals in molecular biology— Science in China and Proceedings of the National Academy of Sciences of the United States of America, there were significant differences between Chinese and English scientific articles in use of hedges.


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