Adaptable Information Provisioning in Collaborative Networks

2011 ◽  
Vol 2 (4) ◽  
pp. 44-56
Author(s):  
Heiko Thimm ◽  
Karsten Boye Rasmussen

Well-informed network participants are a necessity for successful collaboration in business networks. The widespread knowledge of the many aspects of the network is an effective vehicle to promote trust within the network, successfully resolve conflicts, and build a prospering collaboration climate. Despite their natural interest in being well informed about all the different aspects of the network, limited resources, e.g. time restrictions of the participants, often prevents reaching an appropriate level of shared information. It is possible to overcome this problem through the use of an active information provisioning service that allows users to adapt the provisioning of information to their specific needs. This paper presents an extensible information modeling framework and also additional complementary concepts that are designed to enable such an active provisioning service. Furthermore, a high-level architecture for a system that offers the targeted information provisioning service is described.

Author(s):  
Heiko Thimm ◽  
Karsten Boye Rasmussen

Well-informed network participants are a necessity for successful collaboration in business networks. The widespread knowledge of the many aspects of the network is an effective vehicle to promote trust within the network, successfully resolve conflicts, and build a prospering collaboration climate. Despite their natural interest in being well informed about all the different aspects of the network, limited resources, e.g. time restrictions of the participants, often prevents reaching an appropriate level of shared information. It is possible to overcome this problem through the use of an active information provisioning service that allows users to adapt the provisioning of information to their specific needs. This paper presents an extensible information modeling framework and also additional complementary concepts that are designed to enable such an active provisioning service. Furthermore, a high-level architecture for a system that offers the targeted information provisioning service is described.


Author(s):  
Mateusz Iwo Dubaniowski ◽  
Hans Rudolf Heinimann

A system-of-systems (SoS) approach is often used for simulating disruptions to business and infrastructure system networks allowing for integration of several models into one simulation. However, the integration is frequently challenging as each system is designed individually with different characteristics, such as time granularity. Understanding the impact of time granularity on propagation of disruptions between businesses and infrastructure systems and finding the appropriate granularity for the SoS simulation remain as major challenges. To tackle these, we explore how time granularity, recovery time, and disruption size affect the propagation of disruptions between constituent systems of an SoS simulation. To address this issue, we developed a high level architecture (HLA) simulation of three networks and performed a series of simulation experiments. Our results revealed that time granularity and especially recovery time have huge impact on propagation of disruptions. Consequently, we developed a model for selecting an appropriate time granularity for an SoS simulation based on expected recovery time. Our simulation experiments show that time granularity should be less than 1.13 of expected recovery time. We identified some areas for future research centered around extending the experimental factors space.


2014 ◽  
Vol 37 ◽  
pp. 1-10 ◽  
Author(s):  
Peter E.D. Love ◽  
Jane Matthews ◽  
Ian Simpson ◽  
Andrew Hill ◽  
Oluwole A. Olatunji

2013 ◽  
Vol 57 (9) ◽  
pp. 4290-4299 ◽  
Author(s):  
Vici Varghese ◽  
Yumi Mitsuya ◽  
W. Jeffrey Fessel ◽  
Tommy F. Liu ◽  
George L. Melikian ◽  
...  

ABSTRACTThe many genetic manifestations of HIV-1 protease inhibitor (PI) resistance present challenges to research into the mechanisms of PI resistance and the assessment of new PIs. To address these challenges, we created a panel of recombinant multi-PI-resistant infectious molecular clones designed to represent the spectrum of clinically relevant multi-PI-resistant viruses. To assess the representativeness of this panel, we examined the sequences of the panel's viruses in the context of a correlation network of PI resistance amino acid substitutions in sequences from more than 10,000 patients. The panel of recombinant infectious molecular clones comprised 29 of 41 study-defined PI resistance amino acid substitutions and 23 of the 27 tightest amino acid substitution clusters. Based on their phenotypic properties, the clones were classified into four groups with increasing cross-resistance to the PIs most commonly used for salvage therapy: lopinavir (LPV), tipranavir (TPV), and darunavir (DRV). The panel of recombinant infectious molecular clones has been made available without restriction through the NIH AIDS Research and Reference Reagent Program. The public availability of the panel makes it possible to compare the inhibitory activities of different PIs with one another. The diversity of the panel and the high-level PI resistance of its clones suggest that investigational PIs active against the clones in this panel will retain antiviral activity against most if not all clinically relevant PI-resistant viruses.


1998 ◽  
Vol 51 (3) ◽  
pp. 421-429
Author(s):  
Julia Englesou ◽  
Mary Lekakou ◽  
Ernest Tzannatos

Among the many primary causes which lead to a shipping casualty, those of wrecking, stranding or coming into contact with fixed coastal structures depend (although not exclusively and only under specific conditions of visibility) upon the efficiency of the lighthouse and navigating lights network of a national coastline. The analysis of the shipping casualties involving Greek ships in the Greek seas revealed that, despite the recent introduction of sophisticated navigating aids for the prevention of stranding and contact, the share of the corresponding casualties remains unchanged. It appears that for coastal shipping operations, and in particular for port approaches, the traditional light navigating aids are and will always provide an irreplaceable safety service for navigators. This is mainly attributed to their technological simplicity which offers a high level of signal reliability and friendliness for the navigator.


SIMULATION ◽  
1999 ◽  
Vol 73 (5) ◽  
pp. 281-287 ◽  
Author(s):  
Mikel D. Petty ◽  
Piotr S. Windyga

2012 ◽  
Vol 204-208 ◽  
pp. 4952-4957
Author(s):  
Ji Hua Ye ◽  
Qi Xie ◽  
Yao Hong Xiahou

Researched how the multi-pipeline processor accelerates the running of thread ,found that when the branch predictor facing the random branch instruction, the hit rate will become very low, so bring out a new method that using the free pipeline to accelerate the running of branch instruction. If the right prediction from branch predictor is less than 70% and there is a free pipeline, then using two pipelines to run the two sides of a branch instruction at the same time. In order to test the new method, the HLA (High Level architecture) architecture-based simulation system is established, the results show that the new method can really reduce the time when processing the random branch instructions.


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