scholarly journals Assessment of Crystal Morphology on Uptake, Particle Dissolution, and Toxicity of Nanoscale Titanium Dioxide on Artemia Salina

2017 ◽  
Vol 2 (1) ◽  
pp. 11-27 ◽  
Author(s):  
Martha S. Johnson ◽  
Mehmet Ates ◽  
Zikri Arslan ◽  
Ibrahim O. Farah ◽  
Coneliu Bogatu
Keyword(s):  
Oxidative Stress ◽  
Crystal Structure ◽  
Crystal Morphology ◽  
Artemia Salina ◽  
Toxic Effects ◽  
Short Term ◽  
Physico Chemical ◽  
And Oxidative Stress ◽  
Nanoscale Titanium Dioxide

Knowledge of nanomaterial toxicity is critical to avoid adverse effects on human and environment health. In this study, the influences of crystal morphology on physico-chemical and toxic properties of nanoscale TiO2 (n- TiO2) were investigated. Artemia salina were exposed to anatase, rutile and mixture polymorphs of n-TiO2 in seawater. Short-term (24 h) and long-term (96 h) exposures were conducted in 1, 10 and 100 mg/L suspensions of n-TiO2 in the presence and absence of food. Anatase form had highest accumulation followed by mixture and rutile. Presence of food greatly reduced accumulation. n-TiO2 dissolution was not significant in seawater (p<0.05) nor was influenced from crystal structure. Highest toxic effects occurred in 96h exposure in the order of anatase>mixture>rutile. Mortality and oxidative stress levels increased with increasing n-TiO2 concentration and exposure time (p<0.05). Presence of food in the exposure medium alleviated the oxidative stress, indicating deprivation from food could promote toxic effects of n-TiO2 under long-term exposure.

scholarly journals Elevated exposure to prenatal thyroid hormones affects embryonic mortality but has no clear effects into adulthood

2019 ◽  
Author(s):  
Tom Sarraude ◽  
Bin-Yan Hsu ◽  
Ton G.G. Groothuis ◽  
Suvi Ruuskanen
Keyword(s):  
Oxidative Stress ◽  
Thyroid Hormones ◽  
Hatching Success ◽  
Long Term Effects ◽  
Short Term ◽  
Short And Long Term ◽  
Long Term Consequences ◽  
Maternal Thyroid ◽  
And Oxidative Stress

AbstractMaternal thyroid hormones (THs) are known to be crucial in embryonic development in humans, but their influence on other, especially wild, animals remains poorly understood. So far, the studies that experimentally investigated the consequences of maternal THs focused on short-term effects, while early organisational effects with long-term consequences, as shown for other prenatal hormones, could also be expected. In this study, we aimed at investigating both the short- and long-term effects of prenatal THs in a bird species, the Japanese quail Coturnix japonica. We experimentally elevated yolk TH content (the prohormone T4, and its active metabolite T3, as well as a combination of both hormones). We analysed hatching success, embryonic development, offspring growth and oxidative stress as well as their potential organisational effects on reproduction, moult, and oxidative stress in adulthood. We found that eggs injected with both hormones had a higher hatching success compared with control eggs, suggesting conversion of T4 into T3 by the embryo. We detected no other clear short-term or long-term effects of yolk THs. These results suggest that yolk thyroid hormones are important in the embryonic stage of precocial birds, but other short- and long-term consequences remain unclear. Research on maternal thyroid hormones will greatly benefit from studies investigating how embryos use and respond to this maternal signalling. Long-term studies on prenatal THs in other taxa in the wild are needed for a better understanding of this hormone-mediated maternal pathway.

scholarly journals Testing the short-and long-term effects of elevated prenatal exposure to different forms of thyroid hormones

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10175
Author(s):  
Tom Sarraude ◽  
Bin-Yan Hsu ◽  
Ton Groothuis ◽  
Suvi Ruuskanen
Keyword(s):  
Oxidative Stress ◽  
Embryonic Development ◽  
Thyroid Hormones ◽  
Hatching Success ◽  
Long Term Effects ◽  
Short Term ◽  
Short And Long Term ◽  
Long Term Consequences ◽  
And Oxidative Stress

Maternal thyroid hormones (THs) are known to be crucial in embryonic development in humans, but their influence on other, especially wild, animals remains poorly understood. So far, the studies that experimentally investigated the consequences of maternal THs focused on short-term effects, while early organisational effects with long-term consequences, as shown for other prenatal hormones, could also be expected. In this study, we aimed at investigating both the short- and long-term effects of prenatal THs in a bird species, the Japanese quail Coturnix japonica. We experimentally elevated yolk TH content (the prohormone T4, and its active metabolite T3, as well as a combination of both hormones). We analysed hatching success, embryonic development, offspring growth and oxidative stress as well as their potential organisational effects on reproduction, moult and oxidative stress in adulthood. We found that eggs injected with T4 had a higher hatching success compared with control eggs, suggesting conversion of T4 into T3 by the embryo. We detected no evidence for other short-term or long-term effects of yolk THs. These results suggest that yolk THs are important in the embryonic stage of precocial birds, but other short- and long-term consequences remain unclear. Research on maternal THs will greatly benefit from studies investigating how embryos use and respond to this maternal signalling. Long-term studies on prenatal THs in other taxa in the wild are needed for a better understanding of this hormone-mediated maternal pathway.

Long-term erythropoietin therapy does not affect endothelial markers and oxidative stress in haemodialyzed patients

2013 ◽  
Vol 65 ◽  
pp. 41-42
Author(s):  
Tomasz Domaniewski ◽  
Dariusz Pawlak ◽  
Michał Myśliwiec ◽  
Krystyna Pawlak
Keyword(s):  
Oxidative Stress ◽  
Endothelial Markers ◽  
And Oxidative Stress

SHORT-TERM RESPONSES TO CADMIUM EXPOSURE IN THE ESTUARINE POLYCHAETE LAEONEREIS ACUTA (POLYCHAETA, NEREIDIDAE): SUBCELLULAR DISTRIBUTION AND OXIDATIVE STRESS GENERATION

2006 ◽  
Vol 25 (5) ◽  
pp. 1337 ◽  
Author(s):  
Juliana Zomer Sandrini ◽  
Francesco Regoli ◽  
Daniele Fattorini ◽  
Alessandra Notti ◽  
Alan Ferreira Inácio ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Subcellular Distribution ◽  
Cadmium Exposure ◽  
Stress Generation ◽  
Short Term ◽  
And Oxidative Stress

Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects

Toxicology ◽  
2006 ◽  
Vol 219 (1-3) ◽  
pp. 73-84 ◽  
Author(s):  
Jiunn-Wang Liao ◽  
Jaw-Jou Kang ◽  
Chian-Ren Jeng ◽  
Shao-Kuang Chang ◽  
Ming-Jang Kuo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Line ◽  
Calcium Ion ◽  
Toxic Effects ◽  
C2c12 Myoblast ◽  
Myoblast Cell Line ◽  
Myoblast Cell ◽  
And Oxidative Stress

scholarly journals The Effect of a Short-Term Exposure to Lead on the Levels of Essential Metal Ions, Selected Proteins Related to Them, and Oxidative Stress Parameters in Humans

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Michał Dobrakowski ◽  
Marta Boroń ◽  
Ewa Birkner ◽  
Aleksandra Kasperczyk ◽  
Ewa Chwalińska ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lead Exposure ◽  
Essential Metals ◽  
Short Term ◽  
Oxidative Stress Parameters ◽  
Short Term Exposure ◽  
Exposed Workers ◽  
Occupationally Exposed ◽  
And Oxidative Stress ◽  
Stress Parameters

The present study was designed to explore the possible influence of subacute exposure to lead on the levels of selected essential metals, selected proteins related to them, and oxidative stress parameters in occupationally exposed workers. The study population included 36 males occupationally exposed to lead for 36 to 44 days. Their blood lead level at the beginning of the study was 10.7 ± 7.67 μg/dl and increased to the level of 49.1 ± 14.1 μg/dl at the end of the study. The levels of calcium, magnesium, and zinc increased significantly after lead exposure compared to baseline by 3%, 3%, and 8%, respectively, while the level of copper decreased significantly by 7%. The malondialdehyde (MDA) level and the activities of catalase (CAT) and superoxide dismutase (SOD) did not change due to lead exposure. However, the level of lipid hydroperoxides (LPH) in serum increased significantly by 46%, while the level of erythrocyte lipofuscin (LPS) decreased by 13%. The serum levels of essential metals are modified by a short-term exposure to lead in occupationally exposed workers. A short-term exposure to lead induces oxidative stress associated with elevated levels of LPH but not MDA.

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