Impact Deposition of Radon Progeny (218Po ,214Po and 210Po) on the Surface of Human Blood: In Vitro Study

2011 ◽  
Vol 110-116 ◽  
pp. 2004-2009 ◽  
Author(s):  
Asaad Hamid Ismail ◽  
Mohamad S. Jaafar
Keyword(s):  
Human Blood ◽  
Radon Concentration ◽  
Absorbed Dose ◽  
Blood Component ◽  
Good Efficiency ◽  
Present Design ◽  
Human Blood Samples ◽  
The Impact ◽  
Exposure Technique

This work presented new irradiation technique to estimate the impact of radon's progeny deposition on the human blood surface on some blood diseases, using CR-39Nuclear Track Detectors (NTDs). The results show that the present design has good efficiency and the loss rate of radon concentration was a little. Amount of the loss of radon concentration during the process of mixing blood component did not affect on the efficiency of exposure technique. Therefore, method of mixing blood component process was successful. As well as, human blood exposure to radon gas (2210±5.1Bq/m3) make thrombocytopenia, and no effect on red blood cell. And rate of radon absorbed dose into the human blood samples is high at 20 minutes.

Thermodynamic Properties of Rifampicin Redox Current Peaks in Human Blood Samples Using Nano-Sensor (Carbon Nanotubes / Glassy Carbon Electrode)

2021 ◽  
Vol 43 (1) ◽  
pp. 41-41
Author(s):  
Sura Ali AL ASADI Sura Ali AL ASADI ◽  
Muhammed Mizher RADHI and Wisam Hindawi HOIDY Muhammed Mizher RADHI and Wisam Hindawi HOIDY
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Human Blood ◽  
Electrochemical Technique ◽  
Activation Entropy ◽  
Carbon Electrode ◽  
Different Temperatures ◽  
Human Blood Samples ◽  
The Impact

The cyclic voltammetric electrochemical technique was utilized to investigate the effect of different temperatures on the redox current peaks of rifampicin (RF), a drug commonly used to treat many diseases including tuberculosis (TB), in vitro for human blood medium. A modified working electrode of glassy carbon electrode (GCE) with carbon nanotube (CNT) (CNT / GCE) was used as a sensitive nano-sensor to evaluate the impact of temperature on the blood medium in the presence of RF ions. The results confirmed the presence of two oxidation and one reduction current peaks of RF in blood medium at 0.5, 1, and -0.5 V respectively. The redox current peaks of RF ions in blood medium were enhanced with increasing the temperature from 20 to 36oC. The activation energy (E*) values were determined by applying Arrhenius equation with oxidative and anti-oxidative peaks of Ea*(Ipa)= 9.252 and 11.026 kJ.mol-1.K-1,respectively. Other thermodynamic functions such as the change in each of activation Enthalpy (ΔH*), activation Gibbs energy (ΔG*) and activation Entropy (ΔS*) values were estimated using Eyring equation. The present results of the effects of different temperatures on the blood status in presence of RF lead to the explanation of the oxidative stress of the drug which used in an inflammatory of blood at different temperature.

Thermodynamic Properties of Rifampicin Redox Current Peaks in Human Blood Samples Using Nano-Sensor (Carbon Nanotubes / Glassy Carbon Electrode)

2021 ◽  
Vol 43 (1) ◽  
pp. 41-41
Author(s):  
Sura Ali AL ASADI Sura Ali AL ASADI ◽  
Muhammed Mizher RADHI and Wisam Hindawi HOIDY Muhammed Mizher RADHI and Wisam Hindawi HOIDY
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Human Blood ◽  
Electrochemical Technique ◽  
Activation Entropy ◽  
Carbon Electrode ◽  
Different Temperatures ◽  
Human Blood Samples ◽  
The Impact

The cyclic voltammetric electrochemical technique was utilized to investigate the effect of different temperatures on the redox current peaks of rifampicin (RF), a drug commonly used to treat many diseases including tuberculosis (TB), in vitro for human blood medium. A modified working electrode of glassy carbon electrode (GCE) with carbon nanotube (CNT) (CNT / GCE) was used as a sensitive nano-sensor to evaluate the impact of temperature on the blood medium in the presence of RF ions. The results confirmed the presence of two oxidation and one reduction current peaks of RF in blood medium at 0.5, 1, and -0.5 V respectively. The redox current peaks of RF ions in blood medium were enhanced with increasing the temperature from 20 to 36oC. The activation energy (E*) values were determined by applying Arrhenius equation with oxidative and anti-oxidative peaks of Ea*(Ipa)= 9.252 and 11.026 kJ.mol-1.K-1,respectively. Other thermodynamic functions such as the change in each of activation Enthalpy (ΔH*), activation Gibbs energy (ΔG*) and activation Entropy (ΔS*) values were estimated using Eyring equation. The present results of the effects of different temperatures on the blood status in presence of RF lead to the explanation of the oxidative stress of the drug which used in an inflammatory of blood at different temperature.

scholarly journals Platelet-neutrophil complex formation-a detailed in vitro analysis of murine and human blood samples

2015 ◽  
Vol 99 (5) ◽  
pp. 781-789 ◽  
Author(s):  
Maximilian Mauler ◽  
Julia Seyfert ◽  
David Haenel ◽  
Hannah Seeba ◽  
Janine Guenther ◽  
...  
Keyword(s):  
Complex Formation ◽  
Human Blood ◽  
Blood Samples ◽  
Human Blood Samples ◽  
Vitro Analysis ◽  
In Vitro Analysis

Stability of Fibrinogen Concentrate in Human Blood Samples: An In Vitro Study

2018 ◽  
Vol 183 (suppl_1) ◽  
pp. 183-188 ◽  
Author(s):  
Wenjun Z Martini ◽  
Rodolfo de Guzman ◽  
Michael A Dubick
Keyword(s):  
Human Blood ◽  
In Vitro Study ◽  
Vitro Study ◽  
Fibrinogen Concentrate ◽  
Blood Samples ◽  
Human Blood Samples

scholarly journals Behaviour of Titanium Dioxide Particles in Artificial Body Fluids and Human Blood Plasma

2021 ◽  
Vol 22 (19) ◽  
pp. 10614
Author(s):  
Eva Korábková ◽  
Věra Kašpárková ◽  
Daniela Jasenská ◽  
Dita Moricová ◽  
Eliška Daďová ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Human Blood ◽  
Body Fluids ◽  
Human Blood Plasma ◽  
Tio2 Particles ◽  
Commercial Mixture ◽  
Increased Risk ◽  
The Impact

The growing application of materials containing TiO2 particles has led to an increased risk of human exposure, while a gap in knowledge about the possible adverse effects of TiO2 still exists. In this work, TiO2 particles of rutile, anatase, and their commercial mixture were exposed to various environments, including simulated gastric fluids and human blood plasma (both representing in vivo conditions), and media used in in vitro experiments. Simulated body fluids of different compositions, ionic strengths, and pH were used, and the impact of the absence or presence of chosen enzymes was investigated. The physicochemical properties and agglomeration of TiO2 in these media were determined. The time dependent agglomeration of TiO2 related to the type of TiO2, and mainly to the type and composition of the environment that was observed. The presence of enzymes either prevented or promoted TiO2 agglomeration. TiO2 was also observed to exhibit concentration-dependent cytotoxicity. This knowledge about TiO2 behavior in all the abovementioned environments is critical when TiO2 safety is considered, especially with respect to the significant impact of the presence of proteins and size-related cytotoxicity.

The Measurements of Uranium Concentration in Human Blood in Selected Regions in Iraq Using CR-39 Track Detector

2014 ◽  
Vol 925 ◽  
pp. 679-683 ◽  
Author(s):  
Anees A. Al-Hamzawi ◽  
M.S. Jaafar ◽  
Nada F. Tawfiq
Keyword(s):  
Human Blood ◽  
Fission Track ◽  
Uranium Concentration ◽  
Track Detector ◽  
Residential Area ◽  
Military Operations ◽  
Blood Samples ◽  
Human Blood Samples ◽  
South Of Iraq ◽  
The Impact

The technique of fission track has been applied to determine the concentration of uranium in blood samples for people, male and female of Basrah city (south of Iraq), using CR-39 track detector. During the Gulf Wars I and II in 1991 and 2003 respectively, this city became a place of military operations. The measurements were done for samples of human blood for people to study the impact of exposure in this city as compared to results from Babylon city (central Iraq); the latter is far from exposure locations. The results showed that the uranium concentrations in human blood of people in Basrah city ranged from 0.83 ppb to 2.47 while for people in Babylon city, the uranium concentration ranged from 0.3 ppb to 1.59 ppb. It has also been found that the uranium concentration in human blood samples of people in Basrah city is higher than those of people in Babylon city. Results showed statistically significant differences in the uranium concentration in the residential area.

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