Modeling and Simulation of Pharmaceutical Powder Compaction

2012 ◽  
Vol 217-219 ◽  
pp. 1403-1406
Author(s):  
Guo Ning Si ◽  
Chen Lan

The finite element method was conducted to simulate the pharmaceutical powder compression process by using Drucker–Prager Cap model and elastic-plastic deformation theory. The effects of different friction coefficient on tablet property were systematically studied. The results show that the pressure-density curves shift towards right-hand side with slight decrease at smaller friction coefficient. The fluidity of powder remains the inverse decrease with the friction coefficient, and the density distribution changed more uniform. The maximum Mises stress becomes larger with the friction coefficient increased. The powder displacement decreases near die as the friction coefficient increasing. The research can both predict the tablet property and provide the theory reference for tablet practice production through the finite element analysis of pharmaceutical powder compaction.

2014 ◽  
Vol 721 ◽  
pp. 131-134
Author(s):  
Mi Mi Xia ◽  
Yong Gang Li

To research the load upper bracket of Francis hydroelectric unit, then established the finite-element model, and analyzed the structure stress of 7 operating condition points with the ANSYS software. By the strain rosette test, acquired the data of stress-strain in the area of stress concentration of the upper bracket. The inaccuracy was considered below 5% by analyzing the contradistinction between the finite-element analysis and the test, and match the engineering precision and the test was reliable. The finite-element method could be used to judge the stress of the upper bracket, and it could provide reference for the Structural optimization and improvement too.


Author(s):  
Nikhil Joshi ◽  
Pritha Ghosh ◽  
Jonathan Brewer ◽  
Lawrence Matta

Abstract API RP 1102 provides a method to calculate stresses in buried pipelines due to surface loads resulting from the encroachment of roads and railroads. The API RP 1102 approach is commonly used in the industry, and widely available software allows for quick and easy implementation. However, the approach has several limitations on when it can be used, one of which is that it is limited to pipelines crossing as near to 90° (perpendicular crossing) as practicable. In no case can the crossing be less than 30° . In this paper, the stresses in the buried pipeline under standard highway vehicular loading calculated using the API RP 1102 method are compared with the results of two other methods; an analytical method that accounts for longitudinal and circumferential through wall bending effects, and the finite element method. The benefit of the alternate analytical method is that it is not subject to the limitations of API RP 1102 on crossing alignment or depth. However, this method is still subject to the limitation that the pipeline is straight and at a uniform depth. The fact that it is analytical in nature allows for rapid assessment of a number of pipes and load configurations. The finite element analysis using a 3D soil box approach offers the greatest flexibility in that pipes with bends or appurtenances can be assessed. However, this approach is time consuming and difficult to apply to multiple loading scenarios. Pipeline crossings between 0° (parallel) and 90° (perpendicular) are evaluated in the assessment reported here, even though these are beyond the scope of API RP 1102. A comparison across the three methods will provide a means to evaluate the level of conservatism, if any, in the API RP 1102 calculation for crossing between 30° and 90° . It also provides a rationale to evaluate whether the API RP 1102 calculation can potentially be extended for 0° (parallel) crossings.


2017 ◽  
Vol 2017 ◽  
pp. 1-19 ◽  
Author(s):  
Roman Kvasov ◽  
Lev Steinberg

This paper presents the numerical study of Cosserat elastic plate deformation based on the parametric theory of Cosserat plates, recently developed by the authors. The numerical results are obtained using the Finite Element Method used to solve the parametric system of 9 kinematic equations. We discuss the existence and uniqueness of the weak solution and the convergence of the proposed FEM. The Finite Element analysis of clamped Cosserat plates of different shapes under different loads is provided. We present the numerical validation of the proposed FEM by estimating the order of convergence, when comparing the main kinematic variables with an analytical solution. We also consider the numerical analysis of plates with circular holes. We show that the stress concentration factor around the hole is less than the classical value, and smaller holes exhibit less stress concentration as would be expected on the basis of the classical elasticity.


Author(s):  
C. Dumitras ◽  
I. Cozminca

The electromagnetic forming has the advantage of a minimum forming time, but this is a major obstacle in determining the process’s history of the forming workpiece. Both experimental and theoretical known analysis methods for this process give a discret array of data (only for the displacements). One considers it is more adequate to use the finite element method in studying this process. The main advantage of the finite element analysis is given by the fact that it shows the stress and strain fields in a continuous way during the deformation process. Also, it offers a model from which one can predict the final shape of the part and the possible crack zones. One present a compared study of the experimental and the simulated results achieved of the free bulging aluminum specimens by electromagnetic impulses.


1987 ◽  
Vol 2 (2) ◽  
pp. 115-121
Author(s):  
D. Ho ◽  
P. K. K. Lee ◽  
H. W. Chung ◽  
W. C. Keung

A reinforced concrete folded plate space structure of span 28 m and clear height 9·4 m was constructed as a games hall. The structure was analysed using the finite element method. At the design stage, model tests were carried out to check the accuracy of the method of analysis. To assess the behaviour of the actual structure subject to its self-weight, strains and deflections were monitored during construction both before and after removal of formwork. The tests confirmed that results given by the finite element analysis are of sufficient accuracy for the purpose of design, irrespective of the assumptions involved.


2012 ◽  
Vol 468-471 ◽  
pp. 2413-2416 ◽  
Author(s):  
Chuang Du ◽  
Yan Yan Li ◽  
Rong Guo ◽  
Shi Bin Ma

In order to study the performance of asphalt pavement with function layer under temperature-load coupling action, the thickness of surface layer, the module of surface layer and was analyzed to abtain their influence on the function layer stress using the finite element method. The results clearly indicated that it is very effective to prevent the reflection crack by increasing the thickness of asphalt surface layer and it is not obvious to reduce the reflection crack through enhancing the module of asphalt surface layer.


2012 ◽  
Vol 590 ◽  
pp. 487-491
Author(s):  
Qin Man Fan

The frame is the main part of the force matrix of truck vehicle and the stress state is complex and difficult to design. The finite element method is more accurate for the analysis of the static and dynamic characteristics of the frame, which provide guidance for the frame structure design. Establish finite element model of the frame with the application of ANSYS. According to the mechanical analysis of the model, impose reasonable constraints and load, the most typical of the four conditions in the frame is calculated with the finite element analysis, and predicted the weak parts of the frame according to the frame stress-strain cloud, which provided a very important theoretical basis for the improvement of the frame structure of the frame and optimizing design of the frame.


2021 ◽  
Author(s):  
Muhammad Ardalani-Farsa

The finite element method has been applied in the area of the cervical spine since the 1970's. In the present research work, the finite element method was employed to model, validate and analyze a complete model of the human cervical spine from C1 to T1, including interconnecting intervertebral discs, ligaments and joints. The developed model of the cervical spine was validated by the experimental results presented in the literature. As the values obtained from the finite element analysis were mainly in the range of motion observed in the experiment; it was concluded that the finite element results were consistent with the reported data in the literature. Next, the validated model of the cervical spine was examined under physiological loading modes to locate the areas bearing maximum stress in the cervical spine. Finally, to study the effect of variations in the material properties on the output of the finite element analysis, a material property sensitivity study was conducted to the C3-T1 model of cervical spine. Changes in the material properties of the soft tissues affected the external and internal responses of both the hard and soft tissue components, while changes in those of the hard tissues only affected the internal response of hard tissues.


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