A Novel of L-Serine/Chitosan Electrochemical Sensor for Determination of Paracetamol

2014 ◽  
Vol 599-601 ◽  
pp. 776-781 ◽  
Author(s):  
Fu Neng Tan ◽  
Xue Hui Pang ◽  
Yun Bo Zhou
Keyword(s):  
Electrochemical Sensor ◽  
Electrochemical Impedance ◽  
Potassium Ferricyanide ◽  
Acetate Buffer Solution ◽  
Carbon Electrode ◽  
Practical Application ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Solution Interface

A novel type of L-serine and chitosan modified glassy carbon electrode (L-Ser/CS-GCE) as a electrochemical sensor for determination of paracetamol was fabricated. With potassium ferricyanide as the probe, electrochemical properties of this sensor were characterized via electrochemical impedance spectroscopy(EIS) and measured EIS data were fitted with an equivalent circuit to investigate the detailed information about the electrode/solution interface. The electrochemical behavior of paracetamol on L-Ser/CS-GCE was studied via Cyclic voltammetry(CV). This electrochemical sensor showed an excellent electrocatalytic activity for the oxidation of paracetamol in pH4.9 acetate buffer solution and accelerated electron transfer between the electrode and paracetamol. Linear scan voltammetry (LSV) was used for determination of paracetamol. Peak current increased linearly with increasing paracetamol concentration in the range of 2.0×10-6～1.0×10 -3mol/L and the detection limit was found to be 8.3×10-7mol/L. The electrochemical sensor showed good stability and reproducibility. The practical application of the electrochemical sensor was successfully applied for determining the concentration of paracetamol in commercial acetaminophen tablets.

Preparation and characterization of a poly-o-phenylenediamine film modified glassy carbon electrode as a H2O2 sensor

2013 ◽  
Vol 91 (11) ◽  
pp. 1077-1084 ◽  
Author(s):  
Wenying Zhai ◽  
Xiuying Tian ◽  
Yun Yan ◽  
Yuehua Xu ◽  
Yuechun Zhao ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Electrochemical Impedance ◽  
Monomer Concentration ◽  
Acetate Buffer ◽  
Acetate Buffer Solution ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution

A poly-o-phenylenediamine film modified glassy carbon electrode (PoPD/GC) was successfully prepared by cyclic voltammetry in acetate buffer solution. The polymerization mechanism of oPD is discussed. The impedance behavior and morphology of the PoPD membrane were characterized using cyclic voltammetry, electrochemical impedance spectroscopy, and scanning electron microscopy, respectively. It is discovered that the PoPD/GC prepared only in acetate buffer solution had dual electrocatalytic activity toward the oxidation and reduction of H2O2. The optimal buffer solution pH, scanning rate, monomer concentration, and number of scannings for film forming were 4.2, 0.05 V s−1, 6.0 mmol L−1, and 30, respectively. The linear ranges between the anodic (Δia) or cathodic (Δic) current and H2O2 concentration were 0.07−1.0 × 104 and 0.04−4.5 × 104 μmol L−1, respectively. The corresponding calibration curves were Δia (μA) = 8.03c (mmol L−1) + 6.36 (n = 18, R2 = 0.9989) and Δic (μA) = −5.52c (mmol L−1) − 0.77 (n = 18, R2 = 0.9990) with a detection limit of 0.03 and 0.02 μmol L−1 (S/N = 3), respectively. The PoPD/GC prepared in the optimal conditions showed good stability and quick response (<0.2 s) to H2O2, which was successfully applied to the determination of H2O2 in real water samples with satisfactory results.

scholarly journals Determination of Mercury (II) Ion on Aryl Amide-Type Podand-Modified Glassy Carbon Electrode

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Sevgi Güney ◽  
Gülcemal Yıldız ◽  
Gönül Yapar
Keyword(s):  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Reference Electrode ◽  
Differential Pulse ◽  
Acetate Buffer Solution ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution

A new voltammetric sensor based on an aryl amide type podand, 1,8-bis(o-amidophenoxy)-3,6-dioxaoctane, (AAP) modified glassy carbon electrode, was described for the determination of trace level of mercury (II) ion by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). A well-defined anodic peak corresponding to the oxidation of mercury on proposed electrode was obtained at 0.2 V versus Ag/AgCl reference electrode. The effect of experimental parameters on differential voltammetric peak currents was investigated in acetate buffer solution of pH 7.0 containing 1 × 10−1 mol L−1NaCl. Mercury (II) ion was preconcentrated at the modified electrode by forming complex with AAP under proper conditions and then reduced on the surface of the electrode. Interferences of Cu2+, Pb2+, Fe3+, Cd2+, and Zn2+ions were also studied at two different concentration ratios with respect to mercury (II) ions. The modified electrode was applied to the determination of mercury (II) ions in seawater sample.

scholarly journals A facile graphene oxide based sensor for electrochemical detection of prostate anti-cancer (anti-testosterone) drug flutamide in biological samples

RSC Advances ◽  
2017 ◽  
Vol 7 (41) ◽  
pp. 25702-25709 ◽  
Author(s):  
R. Karthik ◽  
Mani Govindasamy ◽  
Shen-Ming Chen ◽  
Tse-Wei Chen ◽  
J. Vinoth kumar ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Electrochemical Sensor ◽  
Electrochemical Detection ◽  
Glassy Carbon ◽  
Biological Samples ◽  
Cancer Drug ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Anti Cancer

An electrochemical sensor based on graphene oxide modified glassy carbon electrode for the determination of anti-cancer drug flutamide.

The synthesis and characterization of 3D mesoporous CeO2 hollow spheres as a modifier for the simultaneous determination of amlodipine, hydrochlorothiazide and valsartan

2020 ◽  
Vol 12 (13) ◽  
pp. 1767-1778 ◽  
Author(s):  
Najmeh Farvardin ◽  
Shohreh Jahani ◽  
Maryam Kazemipour ◽  
Mohammad Mehdi Foroughi
Keyword(s):  
Electrochemical Sensor ◽  
Glassy Carbon ◽  
Hollow Sphere ◽  
Hollow Spheres ◽  
Synthesis And Characterization ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Mesoporous Ceo2

Electrochemical sensor based on mesoporous CeO2 hollow sphere modified glassy carbon electrode for simultaneous detecting amlodipine, hydrochlorothiazide and valsartan was fabricated.

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