Surface Modification of 316 L Stainless Steel by Sol-Gel Ceramic Coating and its Cytocompatibility

2015 ◽  
Vol 1119 ◽  
pp. 423-427
Author(s):  
Han Lee ◽  
Jiunn Der Liao ◽  
Minh Hien Ngo Thi ◽  
Yu Hui Lin ◽  
Pei Lin Shao ◽  
...  

In this research, sol-gel method was utilized to prepare ceramic coating on medical grade 316 L stainless steel with different annealing temperature, solution constitute and coating layers. As-prepared zirconia film morphology was characterized by scanning electron microscope. The human umbilical vein endothelial cells (HUVECs) were cultured on specimens to evaluate their biocompatibility, with fluorescence staining to observe the morphology of cells. The results showed that annealed zirconia film was improved mechanical properties. According to the bio-evaluation results, HUVECs shows very small difference on proliferation activity on ZrO2coatings compared to 316 L stainless steel, which was shows high difference on proinflammation response test. This indicated that ceramic coating can be indeed less aggressive, which was use for potential future application in surface treatment of stainless steel in scalpels and indwelling needle.

2015 ◽  
Vol 3 (44) ◽  
pp. 8717-8728 ◽  
Author(s):  
Xin Li ◽  
Shuheng Yuan ◽  
Si Chen ◽  
Rifang Luo ◽  
Kaiqin Xiong ◽  
...  

An angiopoietin-1 functionalized surface was establishedviapolydopamine coating and regulated HUVECs survival, proliferation and function.


2013 ◽  
Vol 10 (86) ◽  
pp. 20130411 ◽  
Author(s):  
Yen-Jen Wang ◽  
Teng-Yuan Lo ◽  
Chieh-Hsi Wu ◽  
Dean-Mo Liu

In this communication, we report a facile nanotopographical control over a stainless steel surface via an electrophoretic deposition of colloidal amphiphilic chitosan for preferential growth, proliferation or migration of vascular smooth muscle cells (VSMCs) and human umbilical vein endothelial cells (HUVECs). Atomic force microscopy revealed that the colloidal surface exhibited a deposition time-dependent nanotopographical evolution, wherein two different nanotopographic textures indexed by ‘kurtosis’ ( R kur ) value were easily designed, which were termed as ‘sharp’ (i.e. high peak-to-valley texture) surface and ‘flat’ (i.e. low peak-to-valley texture) surface. Cellular behaviour of VSMCs and HUVECs on both surfaces demonstrated topographically dependent morphogenesis, adherent responses and biochemical properties in comparison with bare stainless steel. The formation of a biofunctionalized surface upon a facile colloidal chitosan deposition envisions the potential application towards numerous biomedical devices, and this is especially promising for cardiovascular stents wherein a new surface with optimized texture can be designed and is expected to create an advantageous environment to stimulate HUVEC growth for improved healing performance.


1994 ◽  
Vol 346 ◽  
Author(s):  
Jean-Francois Quinson ◽  
Chantal Chino ◽  
Anne-Marie De Becdelievre ◽  
Christian Guizard

ABSTRACTZrO2 coatings were obtained by the the alkoxide route and deposited onto stainless steel using the dip coating technique. The starting solutions were prepared by mixing zirconium tetrabutoxide, isopropanol, acetylacetone. The water content for the hydrolitic reaction arose from the atmosphere moisture.Useful information for the structural organization of the zirconia/steel interphase is given by XPS analysis.It is found that during firing treatment, the main components (Fe, Cr, Ni) of the stainless steel diffuse into the ceramic coating. XPS data allow to describe the chemical composition variation from the bulk substrate to the outer coating surface.


2015 ◽  
Vol 593 ◽  
pp. 71-80 ◽  
Author(s):  
Djahida Sidane ◽  
Didier Chicot ◽  
Sabeha Yala ◽  
Salima Ziani ◽  
Hafit Khireddine ◽  
...  

2006 ◽  
Vol 510-511 ◽  
pp. 442-445 ◽  
Author(s):  
Dae Yong Shin ◽  
Kyung Nam Kim ◽  
In-Tak Nam ◽  
Sang Mok Han

ZrO2-SiO2 coatings deposited on 316 L stainless steel were prepared to protect chemically the substrates by sol-gel process using Zr(OC3H7 n)4/Si(OC2H5)4 as precursors. The influence of the ZrO2-SiO2 coatings on the corrosion resistance of the 316 L stainless steel was evaluated with the potentiodynamic polarization curves in deareated 15% H2SO4 solutions at 25, 40 and 50 °C . Comparative test was performed on uncoated one. The values of the electrochemical parameters explain how. ZrO2-SiO2 films increase the resistance of stainless steel against corrosion.


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