Enhance the Biological Properties of Commercial Pure Titanium with Bioactive Glass Coating by Pulsed Laser Deposition

Journal of Biomimetics Biomaterials and Biomedical Engineering ◽

10.4028/www.scientific.net/jbbbe.51.29 ◽

2021 ◽

Vol 51 ◽

pp. 29-37

Author(s):

Alaa A. Mohammed

Keyword(s):

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Antibacterial Property ◽

Pure Titanium ◽

Pulsed Laser ◽

Mouse Fibroblast ◽

Laser Deposition ◽

Biological Behavior ◽

Glass Coating

Titanium is the most broadly employed implant material for the load bearing dental and the orthopedic uses due to its brilliant biological and mechanical characteristics. The aim of the present study is to assay the biological behavior of pure Titanium coated with a bioactive glass coating made by pulsed laser deposition. The coating characteristic and the biological behavior of coated specimens were assessed and compared with uncoated specimens. In vitro biological behavior including bioactivity, biocompatibility and antibacterial property was evaluated. The bioactivity of the specimens was assayed by immersion in a simulated body fluid for various times (7 and 14) days. Biocompatibility was assessed by MTT assay of L929 mouse fibroblast cells after 1, 3 and 5 days. Also, the antibacterial property was evaluated against S. aures by optical density method. The obtained results revealed that the pulsed laser deposited bioactive glass coating significantly improved the potential of Titanium for dental and orthopedic applications.

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45S5 bioactive glass coating on Ti6Al4V alloy using pulsed laser deposition technique

Materials Research Express ◽

10.1088/2053-1591/ab7568 ◽

2020 ◽

Vol 6 (12) ◽

pp. 125428 ◽

Cited By ~ 4

Author(s):

Shazia Shaikh ◽

Sunita Kedia ◽

Ananda Guha Majumdar ◽

Mahesh Subramanian ◽

Sucharita Sinha

Keyword(s):

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Pulsed Laser ◽

Ti6al4v Alloy ◽

Laser Deposition ◽

Glass Coating ◽

Deposition Technique

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Pulsed Laser Deposition and Biocompatibility of Titanium Nitride Coatings

Volume 3: Design, Materials and Manufacturing, Parts A, B, and C ◽

10.1115/imece2012-86330 ◽

2012 ◽

Author(s):

Talisha M. Haywood ◽

Kwadwo M. Darkwa ◽

Ram K. Gupta ◽

Dhananjay Kumar

Keyword(s):

Thin Films ◽

Pulsed Laser Deposition ◽

Bone Cells ◽

Cell Attachment ◽

Pure Titanium ◽

Pulsed Laser ◽

Laser Deposition ◽

Biological Behavior ◽

Stainless Steel 316L ◽

Tin Thin Films

TiN thin films were deposited on pure titanium (99.9 %) and stainless steel (316L) substrates using the pulsed laser deposition (PLD) technique. PLD is a very versatile technique to deposit high quality films and it allows the stoichiometry transfer of a multi-component system from target to deposited film. The crystallographic orientation of the films was studied using the X-ray diffraction technique and the results showed that the films were polycrystalline with the (111) preferred orientation. The hydrophilic/hydrophobicity nature of the films was investigated using contact angle measurements and the results indicated that the TiN coated surfaces were hydrophilic (< 90°). Biocompatibility of the TiN thin films was characterized in terms of cell attachment of bone cells on the surfaces of the coatings. Human bone marrow stromal cells were cultured, seeded, stained and imaged using a fluorescent microscope. Results on the biological behavior of the TiN thin films suggest that TiN is a good biocompatible material and has great promises in biological applications.

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Pulsed laser deposition of magnesium-containing bioactive glass film on porous Ti–6Al–4V substrate pretreated by micro-arc oxidation

Vacuum ◽

10.1016/j.vacuum.2015.12.005 ◽

2016 ◽

Vol 125 ◽

pp. 48-55 ◽

Cited By ~ 26

Author(s):

J. Ma ◽

C.Z. Wang ◽

C.L. Ban ◽

C.Z. Chen ◽

H.M. Zhang

Keyword(s):

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Pulsed Laser ◽

Laser Deposition ◽

Glass Film ◽

Porous Ti ◽

Micro Arc Oxidation

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A study on in vitro and in vivo bioactivity of HA/45S5 composite films by pulsed laser deposition

Applied Surface Science ◽

10.1016/j.apsusc.2013.01.117 ◽

2013 ◽

Vol 270 ◽

pp. 667-674 ◽

Cited By ~ 19

Author(s):

D.G. Wang ◽

C.Z. Chen ◽

Q.S. Ma ◽

Q.P. Jin ◽

H.C. Li

Keyword(s):

Pulsed Laser Deposition ◽

Composite Films ◽

Pulsed Laser ◽

Laser Deposition

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Borate and Silicate Bioactive Glass Coatings Prepared by Nanosecond Pulsed Laser Deposition

Coatings ◽

10.3390/coatings10111105 ◽

2020 ◽

Vol 10 (11) ◽

pp. 1105

Author(s):

Julietta V. Rau ◽

Angela De Bonis ◽

Mariangela Curcio ◽

Katharina Schuhladen ◽

Katia Barbaro ◽

...

Keyword(s):

Thin Films ◽

Bioactive Glass ◽

Pulsed Laser Deposition ◽

Osteogenic Differentiation ◽

Borate Glass ◽

Pulsed Laser ◽

Laser Deposition ◽

Alizarin Red ◽

Nanosecond Pulsed Laser ◽

Biological Tests

Silicate (13-93) and borate (13-93-B3) bioactive glass coatings were successfully deposited on titanium using the nanosecond Pulsed Laser Deposition technique. The coatings’ microstructural characteristics, compositions and morphologies were examined by a number of physico-chemical techniques. The deposited coatings retain the same functional groups of the targets, are a few microns thick, amorphous, compact and crack free. Their surface is characterized by the presence of micrometric and nanometric particles. The surface topography, investigated by Atomic Force Microscopy, is characterized by spherical or ellipsoidal particles of the 0.2–3 μm size range for the 13-93 silicate bioactive glass film and of the 0.1–1 µm range for the 13-93-B3 borate bioactive glass coating. Equine adipose tissue-derived mesenchymal stem cells (ADMSCs) were applied for biological tests and the osteogenic differentiation activity of cells on the deposited coatings was studied after ADMSCs growth in osteogenic medium and staining with Alizarin Red. Cytocompatibility and osteogenic differentiation tests have shown that thin films retain the biocompatibility properties of the target silicate and borate glass, respectively. On the other hand, no antibacterial activity of the borate glass films was observed, suggesting that ion doping is advisable to inhibit bacterial growth on the surface of borate glass thin films.

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