Fibers Obtaining and Characterization Using Poly (Lactic-co-Glycolic Acid) and Poly (Isoprene) Containing Hydroxyapatite and α TCP Calcium Phosphate by Electrospinning Method

2014 ◽  
Vol 631 ◽  
pp. 173-178
Author(s):  
Fernanda Albrecht Vechietti ◽  
D. Marques ◽  
Nathália Oderich Muniz ◽  
Luis Alberto Santos
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Tissue Regeneration ◽  
Morphological Properties ◽  
Polymeric Fibers ◽  
Natural Bone ◽  
Electrospinning Method ◽  
Biological Apatite ◽  
The One

Natural bone is formed by a complex composite, essentially constituted of biological apatite and fibers of collagen. The combination of materials such as biopolymers and bioceramics may result in an interesting material for application in bone tissue regeneration. This work aims to obtain polymeric fibers containing Poly (Lactic-co-Glycolic Acid) and Poly (Isoprene), supplemented with hydroxyapatite (HA) and α-tricalcium phosphate (TCP). The thermal, mechanical and morphological properties of the fibers were evaluated . Even presenting a larger diameter, fibers with α-TCP presented lower elastic modulus than fibers with HA. Both fibers presented similar thermal behavior, with glass transition temperature in the same range that the one presented by raw PLGA and similar degradation temperatures. Is safe to say that the presence of ceramics in the fibers have a potential for further investigations aiming bone tissue regeneration.

Biological and mechanical evaluation of poly(lactic-co-glycolic acid)-based composites reinforced with 1D, 2D and 3D carbon biomaterials for bone tissue regeneration

2017 ◽  
Vol 12 (2) ◽  
pp. 025012 ◽  
Author(s):  
Tejinder Kaur ◽  
Senthilguru Kulanthaivel ◽  
Arunachalam Thirugnanam ◽  
Indranil Banerjee ◽  
Krishna Pramanik
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Tissue Regeneration ◽  
2D And 3D

scholarly journals Carbon Nanostructures in Bone Tissue Engineering

2016 ◽  
Vol 10 (1) ◽  
pp. 877-899 ◽  
Author(s):  
Brian Lee Perkins ◽  
Naghmeh Naderi
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Carbon Nanostructures ◽  
Bone Tissue Regeneration ◽  
Biophysical Properties ◽  
Carbon Nanostructure ◽  
Natural Bone ◽  
Wide Range

Background:Recent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians’ reconstructive armory. Current clinically available reconstructive options have certain advantages, but also several drawbacks that prevent them from gaining universal acceptance. A wide range of synthetic and natural biomaterials is being used to develop tissue-engineered bone. Many of these materials are currently in the clinical trial stage.Methods:A selective literature review was performed for carbon nanostructure composites in bone tissue engineering.Results:Incorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration.Conclusion:This review summarizes the chemical and biophysical properties of carbon nanostructures and discusses their functionality in bone tissue regeneration.

Enhanced osteogenic differentiation and bone regeneration of poly(lactic-co-glycolic acid) by graphene via activation of PI3K/Akt/GSK-3β/β-catenin signal circuit

2018 ◽  
Vol 6 (5) ◽  
pp. 1147-1158 ◽  
Author(s):  
Xiaowei Wu ◽  
Shang Zheng ◽  
Yuanzhou Ye ◽  
Yuchen Wu ◽  
Kaili Lin ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Defects ◽  
Bone Tissue Regeneration ◽  
Autologous Bone ◽  
Potential Strategy ◽  
Gsk 3Β ◽  
Reconstruction Of Bone Defects

The reconstruction of bone defects by guiding autologous bone tissue regeneration with graphene-based biomaterials is a potential strategy in the area of bone tissue engineering.

Preparation of spherical macroporous poly(lactic‐co‐glycolic acid) for bone tissue regeneration

2015 ◽  
Vol 9 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Chunhui Bian ◽  
Huiming Lin ◽  
Xiaofeng Li ◽  
Jie Ma ◽  
Pingping Jiang ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Tissue Regeneration

Release of simvastatin from scaffolds of poly(lactic‐co‐glycolic) acid and biphasic ceramic designed for bone tissue regeneration

2019 ◽  
Vol 107 (6) ◽  
pp. 2152-2164 ◽  
Author(s):  
Isis C. Encarnação ◽  
Mariane B. Sordi ◽  
Águedo Aragones ◽  
Carmen Maria Olivera Müller ◽  
Anderson C. Moreira ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Tissue Regeneration ◽  
Biphasic Ceramic

scholarly journals Load‐bearing biodegradable polycaprolactone‐poly (lactic‐co‐glycolic acid)‐ beta tri‐calcium phosphate scaffolds for bone tissue regeneration

2019 ◽  
Vol 30 (5) ◽  
pp. 1189-1197 ◽  
Author(s):  
Alok Kumar ◽  
Yiren Zhang ◽  
Amalia Terracciano ◽  
Xiao Zhao ◽  
Tsan‐Liang Su ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Glycolic Acid ◽  
Bone Tissue Regeneration ◽  
Load Bearing
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