scholarly journals Seasonal distribution and phylogenetic analysis of human metapneumovirus in children with acute respiratory tract infections admitted to a general hospital in Sri Lanka

2021 ◽  
Vol 11 (0) ◽  
pp. 3
Author(s):  
M. V. M. Divarathna ◽  
R. A. M. Rafeek ◽  
A. J. Morel ◽  
S. Jagoda ◽  
F. Noordeen
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
L. Gayani Tillekeratne ◽  
Champica K. Bodinayake ◽  
Thushani Dabrera ◽  
Ajith Nagahawatte ◽  
Wasantha Kodikara Arachchi ◽  
...  

2021 ◽  
Vol 11 (2) ◽  
pp. 146-150
Author(s):  
Ahmed Osman Gasim Attar ◽  
Khalid Enan ◽  
Sara Abdelghani ◽  
Lienda Bashier Eltayeb

Background: Human metapneumovirus (hMPV) is a major novel cause of acute respiratory infections ranging from wheezing to bronchiolitis and pneumonia in children worldwide. The aim of this study was to detect hMPV in hospitalized children with acute respiratory tract infections (ARTIs) by using reverse transcription-loop mediated isothermal amplification (RT-LAMP) assay. Methods and Results: A total of 68 children with ARTIs who were clinically suspected of acquiring hMPV were included in the study in the period between January 2019 and February 2020. Posterior-pharyngeal (throat) swabs were obtained from each patient. hMPV RNA was revealed in 18(26.5%) cases. The age range was from <1 year to 10 years (mean age of 5.25±2.62). Sixteen (23.5%) of the participants were in the age group of <1 year, where the majority of hMPV-positive subjects (n=11) were found (16.2% of the total number of infected children) (P=0.0025). The majority of hMPV-negative subjects (n=15) were found in the age group of 5-10 years (22% of the total number of infected children) (P=0.0025). Cough, fever, and shortness of breath were common symptoms in hMPV-positive children: 15(83.3%), 13(72.2%), and 12(66.7%), respectively. There was a statistically significant correlation between common clinical symptoms and the age group of hMPV-positive children: symptoms were common in the age group of <1 year. Conclusion: Our study represents the first report in Khartoum, Sudan, on the detection of hMPV using RT-LAMP. RT-LAMP is a valuable, quick diagnostic technique for hMPV detection.


Author(s):  
Rafea B. ◽  
Alharbi F. ◽  
Alhazmi G. ◽  
Alahmadi L. ◽  
Almotiri M. ◽  
...  

Introduction: In general practice, approximately two-thirds of antibiotic prescriptions are for respiratory tract infections. Acute respiratory tract infections, which include acute uncomplicated bronchitis, pharyngitis, rhinosinusitis and the common cold, are often common reasons for acute outpatient visits to physicians and antibiotic prescriptions for adults. The improper treatment of acute respiratory tract infections is now an urgent public health threat, as it is an important contributor to antibiotic resistance. In developing countries, including Saudi Arabia, antibiotics are prescribed excessively and are often obtained without prescription. Aim: The aim of this study was to gather information on current antibiotic prescribing rates for respiratory tract infection in Hera General Hospital Makkah Almukarramah, Saudi Arabia. Method: A cross-sectional study, incorporating systematic sampling on clinical data from antibiotic prescriptions in hospitalised and emergency departments at Hera General Hospital, was conducted. From September 2017 to April 2018, approximately 500 prescriptions were collected from each hospitalised and emergency pharmacy for patients with respiratory tract infections. Results: The most prescribed antibiotics for respiratory tract infections came from the penicillin group and ciprofloxacin. The prescribing of antibiotics for respiratory tract infections was more prevalent amongst males than females. Potential over-prescribing of antibiotics for upper respiratory tract infections specially patients with otitis media especially in children without proper lab investigations.


Sign in / Sign up

Export Citation Format

Share Document