scholarly journals MD-2 Enables Toll-Like Receptor 2 (TLR2)-Mediated Responses to Lipopolysaccharide and Enhances TLR2-Mediated Responses to Gram-Positive and Gram-Negative Bacteria and Their Cell Wall Components

2001 ◽  
Vol 166 (3) ◽  
pp. 1938-1944 ◽  
Author(s):  
Roman Dziarski ◽  
Qiuling Wang ◽  
Kensuke Miyake ◽  
Carsten J. Kirschning ◽  
Dipika Gupta
Keyword(s):  
Cell Wall ◽  
Gram Negative Bacteria ◽  
Toll Like Receptor ◽  
Gram Positive ◽  
Gram Negative ◽  
Cell Wall Components ◽  
Toll Like Receptor 2 ◽  
Wall Components

scholarly journals Gram Positive Bacterial Lipoteichoic Acid Role in a Root Canal Infection – A Literature Review

2021 ◽  
Author(s):  
Vinoo Subramaniam Ramachandran ◽  
Mensudar Rathakrishnan ◽  
Malathy Balaraman Ravindrran ◽  
Alargarsamy Venkatesh ◽  
Vidhya Shankari Shanmugasundaram ◽  
...  
Keyword(s):  
Cell Wall ◽  
Immune Surveillance ◽  
Lipoteichoic Acid ◽  
The Body ◽  
Gram Positive ◽  
Gram Negative ◽  
Cell Wall Components ◽  
Root Canals ◽  
Endodontic Infection ◽  
Wall Components

Bacteria and its by-products are found to be the main cause of pulpal and periapical infection of tooth. Infected root canals of tooth harbours a wide variation of microbial flora that includes both Gram-positive and Gram-negative microorganisms. Bacterial components such as Lipopolysaccharide (LPS) of gram negative bacteria and Lipoteichoic Acid (LTA) of gram positive bacteria have the potential to enter the peri-apical tissue of tooth and initiate the inflammatory process. After microbial death that occurs either due to body’s defence cells or by antibiotic action, bacterial cell wall components such as LTA are released which can persist inside macrophages for prolonged periods causing chronic inflammation. Once these cell-wall components are recognized by the body immune surveillance cells, numerous inflammatory mediators are released leading to inflammation and subsequent pathological consequences. The purpose of this review is intend to summarize the role of gram positive bacterial component LTA in causing endodontic infection and use of potential therapeutic agents against LTA.

scholarly journals Lipoprotein is a predominant Toll-like receptor 2 ligand in Staphylococcus aureus cell wall components

2005 ◽  
Vol 18 (2) ◽  
pp. 355-362 ◽  
Author(s):  
Masahito Hashimoto ◽  
Kazuki Tawaratsumida ◽  
Hiroyuki Kariya ◽  
Kazue Aoyama ◽  
Toshihide Tamura ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Wall ◽  
Toll Like Receptor ◽  
Cell Wall Components ◽  
Toll Like Receptor 2 ◽  
Wall Components

scholarly journals Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

Immunity ◽  
1999 ◽  
Vol 11 (4) ◽  
pp. 443-451 ◽  
Author(s):  
Osamu Takeuchi ◽  
Katsuaki Hoshino ◽  
Taro Kawai ◽  
Hideki Sanjo ◽  
Haruhiko Takada ◽  
...  
Keyword(s):  
Cell Wall ◽  
Bacterial Cell ◽  
Bacterial Cell Wall ◽  
Gram Positive ◽  
Gram Negative ◽  
Cell Wall Components ◽  
Wall Components
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