scholarly journals Comparison of Morphological Quantitative Characteristics of the Newly Formed Alveolar Bone After the Application of Demineralized Bone Matrix and Cortical Bone Allografts

2019 ◽  
Vol 37 (4) ◽  
pp. 1509-1516
Author(s):  
Fernando José Dias ◽  
Alain Arias ◽  
Eduardo Borie ◽  
Maria Florencia Lezcano ◽  
Manuel Arellano-Villalón ◽  
...  
Keyword(s):  
Cortical Bone ◽  
Alveolar Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Allografts ◽  
Quantitative Characteristics ◽  
Demineralized Bone

Accelerated repair of cortical bone defects using a synthetic extracellular matrix to deliver human demineralized bone matrix

2006 ◽  
Vol 24 (7) ◽  
pp. 1454-1462 ◽  
Author(s):  
Yanchun Liu ◽  
Shama Ahmad ◽  
Xiao Zheng Shu ◽  
R. Kent Sanders ◽  
Sally Anne Kopesec ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Cortical Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Defects ◽  
Demineralized Bone

Periodontal Repair in Dogs: Effect of Allogenic Freeze-Dried Demineralized Bone Matrix Implants on Alveolar Bone and Cementum Regeneration

1998 ◽  
Vol 69 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Chong-Kwan Kim ◽  
Kyoo-Sung Cho ◽  
Seong-Ho Choi ◽  
Annamarie Prewett ◽  
Ulf M.E. Wikesjö
Keyword(s):  
Alveolar Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Freeze Dried ◽  
Demineralized Bone

Ectopic Osteoinduction by Variously Demineralized Allogenic Cortical Bone Matrix

2007 ◽  
Vol 342-343 ◽  
pp. 105-108
Author(s):  
J.T. Kim ◽  
H.J. Kang ◽  
H.N. Kim ◽  
J.Y. Choi ◽  
J.M. Lee ◽  
...  
Keyword(s):  
Bone Formation ◽  
Cortical Bone ◽  
Cellular Proliferation ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Ectopic Bone Formation ◽  
Bioactive Molecules ◽  
Muscular Tissue ◽  
Ectopic Bone ◽  
Demineralized Bone

To improve ostegenic healing efficiency by demineralized bone matrix, we evaluated the ectopic bone formation induced by variously demineralized allogenic cortical bone matrices at subcutaneous and muscular sites in rats. The rat tubular cortical bone matrices were demineralized in heated 0.6N HCl at 60 °C for 5 and 20 mins, respectively, using a controlledheat ultrasonic cleaner and implanted in rat dorsal subcutaneous pouches and thigh muscles for 1-3 weeks. The influence of the demineralized condition of bone matrix on cellular proliferation and osteogenic differentiation was also evaluated in vitro by MTT assay and ALP staining. The cortical matrices were completely demineralized within 20 mins by sonication and heating of diluted 0.6 N HCl. The sonicated bone matrices in heated acidic solution at 60 °C revealed no adverse immunogenic and inflammatory response in vivo regardless of demineralized condition. Cellular proliferation and osteoblastic differentiation was facilitated by more fully demineralized. Ectopic bone formation was induced only by demineralized bone matrices and were more favorable in fully demineralized matrices. The ectopic bone induction was more favorably in subcutaneous pouches than in muscular tissue. These findings suggest that a fully demineralized cortical bone matrix maximizes osteogenic repair by exposing more bioactive molecules which in turn induce chondro- and osteognic differentiation of mesenchymal cells around the implanted matrices, and that the sonication of diluted 0.6 N HCl heated at 60 ° C is a rapid and effective method for sterile demineralized graft preparation.

Effect of allogeneic freeze-dried demineralized bone matrix on regeneration of alveolar bone and periodontal attachment in dogs

1998 ◽  
Vol 25 (10) ◽  
pp. 801-806 ◽  
Author(s):  
Nicholas Caplanis ◽  
Michael B. Lee ◽  
Grenith J. Zimmerman ◽  
Knut A. Selvig ◽  
Ulf M.E. Wikesjo
Keyword(s):  
Alveolar Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Freeze Dried ◽  
Periodontal Attachment ◽  
Demineralized Bone
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