scholarly journals Peyronie’s disease: A “triple oxygenant therapy”

2013 ◽  
Vol 85 (1) ◽  
pp. 36 ◽  
Author(s):  
Francesco Ciociola ◽  
Giovanni Maria Colpi

Objectives: To evaluate the effects of upregulators of nitric oxide in one patient with Peyronie’s disease, after non significant improvement following intracavernosal verapamil. Methods: A 20-years-old Caucasian male presented with penile induration in flaccid state, persistent during erection and associated with mild pain at third middle of penis. After treatment with intracavernosal verapamil for 4 months with relief of penile discomfort, followed by counseling on the use of penile extender for at least 6 hours per day, he was prescribed pentoxifylline associated with tadalafil plus levo-arginine, propionil-carnitine and Vitamin B3. Results: After almost 2 years, the septal thickness was reduced at ultrasound evaluation after this “triple oxygenant therapy”. Conclusion: NO-iNOS biology in Peyronie patients is the very protagonist in modulating penile fibrosis through up-regulation of NO-cGMP pathway that influences penile health by preventing and reversing fibrosis in the tunical albuginea.

1995 ◽  
pp. 1122-1125 ◽  
Author(s):  
Rolf Vosshenrich ◽  
Immo Schroeder-Printzen ◽  
Wolfgang Weidner ◽  
Uwe Fischer ◽  
Matthias Funke ◽  
...  

2018 ◽  
Vol 51 (4) ◽  
pp. 257-261 ◽  
Author(s):  
Maitê Aline Vieira Fernandes ◽  
Luis Ronan Marquez Ferreira de Souza ◽  
Luciano Pousa Cartafina

Abstract Ultrasound is an excellent method for the study of penis. In this article, using a critical review of the literature and teaching files, we present examples of the major findings in the ultrasound routine, focusing on trauma, priapism, Peyronie's disease, and erectile dysfunction.


1995 ◽  
Vol 153 (4) ◽  
pp. 1122-1125 ◽  
Author(s):  
Rolf Vosshenrich ◽  
Immo Schroeder-Printzen ◽  
Wolfgang Weidner ◽  
Uwe Fischer ◽  
Matthias Funke ◽  
...  

Author(s):  
Юрий Заседа

Relevance. The spectrum of combined mechanisms of action of PRP-therapy, LISWT and LNP therapy suggests the clinical eff ect for patients with fi broplastic penile induration, which currently does not have conservative therapies that have suffi cient effi cacy.The aim of the study was to determine the effi cacy of combined PRP-therapy with intracavernous activation of growth factors by LISWT method + LNP and ICA pharmacotherapy in treatment of fi broplastic penile induction.Design. The study group comprised 23 patients of the Men’s Health Clinic in Kyiv, suff ering from fi broplastic penile inducing (Peyronie’s disease, ICD-10: N48.6) with erectile dysfunction.Results of the study. A 6-month follow-up observation showed a reduction of pain during erection, a signifi cant improvement in erectile function, a total regression of the areas less than 25 mm2 and a signifi cant decrease in the density and area of the induration areas that over 25 mm2. Conclusions. It has been established that the therapeutic model of the combined use of PRP-therapy with intracavernous activation of growth factors by LISWT method + LOD + ICA in the treatment of fi broplastic penile induration, shows a pronounced clinical eff ect, which makes this therapeutic model a promising option for conservative correction of pain and erectile dysfunction in fi broplastic penile induration.


1992 ◽  
Vol 2 (3) ◽  
pp. 230-232 ◽  
Author(s):  
G. Helweg ◽  
W. Judmaier ◽  
K. Wicke ◽  
A. Oberhauser ◽  
D. zur Nedden ◽  
...  

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