scholarly journals Minimum performance level definition for bone plate testing according to standard: A preliminary study

2021 ◽  
Vol 4 (s1) ◽  
Author(s):  
Federico A. Bologna ◽  
Mara Terzini ◽  
Andrea T. Lugas ◽  
Alberto L. Audenino
Keyword(s):  
Medical Devices ◽  
In Silico ◽  
Experimental Tests ◽  
Experimental Results ◽  
Orthopedic Device ◽  
Device Implantation ◽  
In Silico Modeling ◽  
Preliminary Study ◽  
Time Required ◽  
Minimum Performance

In silico modeling of osteosynthesis medical devices allows the reduction of the time required for experimental tests and the introduction of “simulation-driven design”. Using a wise combination of these techniques and analytical calculations, it is possible to relate the experimental results, which are mandatory for regulatory purposes, to the plate physiological application and prevent the occurrence of complications in the early stages after the orthopedic device implantation on humans and animals.

Yaw Galloping of a TLWP Platform Under High Speed Currents by Analytical Methods and its Comparison With Experimental Results

2017 ◽  
Author(s):  
Francisco Lamas ◽  
Miguel A. M. Ramirez ◽  
Antonio Carlos Fernandes
Keyword(s):  
High Speed ◽  
Production Systems ◽  
Experimental Tests ◽  
Experimental Results ◽  
Analytical Methodology ◽  
New Approach ◽  
Laboratory Facilities ◽  
Polynomial Curve ◽  
Computational Fluid Dynamics Cfd ◽  
Cfd Analyses

Flow Induced Motions are always an important subject during both design and operational phases of an offshore platform life. These motions could significantly affect the performance of the platform, including its mooring and oil production systems. These kind of analyses are performed using basically two different approaches: experimental tests with reduced models and, more recently, with Computational Fluid Dynamics (CFD) dynamic analysis. The main objective of this work is to present a new approach, based on an analytical methodology using static CFD analyses to estimate the response on yaw motions of a Tension Leg Wellhead Platform on one of the several types of motions that can be classified as flow-induced motions, known as galloping. The first step is to review the equations that govern the yaw motions of an ocean platform when subjected to currents from different angles of attack. The yaw moment coefficients will be obtained using CFD steady-state analysis, on which the yaw moments will be calculated for several angles of attack, placed around the central angle where the analysis is being carried out. Having the force coefficients plotted against the angle values, we can adjust a polynomial curve around each analysis point in order to evaluate the amplitude of the yaw motion using a limit cycle approach. Other properties of the system which are flow-dependent, such as damping and added mass, will also be estimated using CFD. The last part of this work consists in comparing the analytical results with experimental results obtained at the LOC/COPPE-UFRJ laboratory facilities.

scholarly journals In silico imaging clinical trials: cheaper, faster, better, safer, and more scalable

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Aldo Badano
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Medical Devices ◽  
In Silico ◽  
Lessons Learned ◽  
Patient Access ◽  
High Quality ◽  
Virtual Imaging ◽  
Regulatory Evaluation

AbstractImaging clinical trials can be burdensome and often delay patient access to novel, high-quality medical devices. Tools for in silico imaging trials have significantly improved in sophistication and availability. Here, I describe some of the principal advantages of in silico imaging trials and enumerate five lessons learned during the design and execution of the first all-in silico virtual imaging clinical trial for regulatory evaluation (the VICTRE study).

scholarly journals 2021 Biomaterials Science Emerging Investigators Issue In-silico design of additively manufacturable composite synthetic vascular conduits and grafts with tuneable compliance

2021 ◽  
Author(s):  
Oisín Sean Byrne ◽  
Fergal Brian Coulter ◽  
Ellen T Roche ◽  
Eoin D O'Cearbhaill
Keyword(s):  
Medical Devices ◽  
Clinical Assessment ◽  
In Silico ◽  
Critical Part ◽  
In Silico Design ◽  
Physiological Conditions

Benchtop testing of endovascular medical devices under accurately simulated physiological conditions is a critical part of device evaluation prior to clinical assessment. Currently, glass, acrylic and silicone vascular models are...

In Silico Modeling as a Tool to Predict and Characterize Plant Toxicity

2020 ◽  
pp. 367-378
Author(s):  
Charles Oluwaseun Adetunji ◽  
William Peter Mitembo ◽  
Chukwuebuka Egbuna ◽  
G.M. Narasimha Rao
Keyword(s):  
In Silico ◽  
Plant Toxicity ◽  
In Silico Modeling

scholarly journals In silico modeling gas molecules transfer through the biomembrane by kinks-solitons

2021 ◽  
Author(s):  
P. V. Mokrushnikov ◽  
E. V. Lezhnev ◽  
V. Ya. Rudyak
Keyword(s):  
In Silico ◽  
In Silico Modeling ◽  
Gas Molecules
Sign in / Sign up

Export Citation Format

Share Document