scholarly journals Extrapulmonary features of bronchiectasis: muscle function, exercise capacity, fatigue, and health status

2012 ◽  
Vol 7 ◽  
Author(s):  
Ozge Ozalp ◽  
Deniz Inal-Ince ◽  
Ebru Calik ◽  
Naciye Vardar-Yagli ◽  
Melda Saglam ◽  
...  
Keyword(s):  
Health Status ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Muscle Function ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Muscle Endurance ◽  
Respiratory Muscle Strength ◽  
Peripheral Muscle ◽  
6Mwt Distance

Background: There are limited number of studies investigating extrapulmonary manifestations of bronchiectasis. The purpose of this study was to compare peripheral muscle function, exercise capacity, fatigue, and health status between patients with bronchiectasis and healthy subjects in order to provide documented differences in these characteristics for individuals with and without bronchiectasis. Methods: Twenty patients with bronchiectasis (43.5 ± 14.1 years) and 20 healthy subjects (43.0 ± 10.9 years) participated in the study. Pulmonary function, respiratory muscle strength (maximal expiratory pressure – MIP - and maximal expiratory pressure - MEP), and dyspnea perception using the Modified Medical Research Council Dyspnea Scale (MMRC) were determined. A six-minute walk test (6MWT) was performed. Quadriceps muscle, shoulder abductor, and hand grip strength (QMS, SAS, and HGS, respectively) using a hand held dynamometer and peripheral muscle endurance by a squat test were measured. Fatigue perception and health status were determined using the Fatigue Severity Scale (FSS) and the Leicester Cough Questionnaire (LCQ), respectively. Results: Number of squats, 6MWT distance, and LCQ scores as well as lung function testing values and respiratory muscle strength were significantly lower and MMRC and FSS scores were significantly higher in patients with bronchiectasis than those of healthy subjects (p<0.05). In bronchiectasis patients, QMS was significantly associated with HGS, MIP and MEP (p<0.05). The 6MWT distance was significantly correlated to LCQ psychological score (p<0.05). The FSS score was significantly associated with LCQ physical and total and MMRC scores (p<0.05). The LCQ psychological score was significantly associated with MEP and 6MWT distance (p<0.05). Conclusions: Peripheral muscle endurance, exercise capacity, fatigue and health status were adversely affected by the presence of bronchiectasis. Fatigue was associated with dyspnea and health status. Respiratory muscle strength was related to peripheral muscle strength and health status, but not to fatigue, peripheral muscle endurance or exercise capacity. These findings may provide insight for outcome measures for pulmonary rehabilitation programs for patients with bronchiectasis.

Relationship between respiratory muscle function and age, sex, and other factors

1989 ◽  
Vol 66 (2) ◽  
pp. 943-948 ◽  
Author(s):  
H. I. Chen ◽  
C. S. Kuo
Keyword(s):  
Muscle Strength ◽  
Pulmonary Function ◽  
Duty Cycle ◽  
Muscle Function ◽  
Respiratory Muscle ◽  
Forced Expiratory Volume ◽  
Inspiratory Muscle ◽  
Muscle Endurance ◽  
Respiratory Muscle Strength ◽  
Respiratory Muscle Function

To investigate the effects of gender and age on respiratory muscle function, 160 healthy volunteers (80 males, 80 females) were divided into four age groups. Twenty-eight of the male subjects were smokers. After the subjects were familiarized with the experimental procedure, respiratory muscle strength, inspiratory muscle endurance, and spirometric function, including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), FEV1/FVC, tidal volume, breathing rate, and duty cycle, were measured. The respiratory muscle strength was indicated by the maximal static inspiratory and expiratory pressures (PImmax and PEmmax). Inspiratory muscle endurance was determined by the time the subject was able to sustain breathing against an inspiratory pressure load on a modified Nickerson-Keens device. The results showed that 1) except for inspiratory muscle endurance and FEV1/FVC, men had greater respiratory muscle and pulmonary functions than women, 2) respiratory muscle function and pulmonary function decreased with age, 3) smoking tended to lower duty cycle and FEV1/FVC and to enhance PE,mmax, and 4) inspiratory muscle endurance was greater in men who were physically active than in those who were sedentary. Therefore we conclude that there are sexual and age differences in respiratory muscle strength and pulmonary function and that smoking or physical activity may affect respiratory muscle function.

scholarly journals Muscle function and quality of life in the Crohn’s disease

2017 ◽  
Vol 30 (2) ◽  
pp. 337-345 ◽  
Author(s):  
Andrea Lemos Cabalzar ◽  
Diana Junqueira Fonseca Oliveira ◽  
Maycon de Moura Reboredo ◽  
Fernando Azevedo Lucca ◽  
Júlio Maria Fonseca Chebli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Muscle Function ◽  
Respiratory Muscle ◽  
Control Group ◽  
Respiratory Muscle Strength ◽  
Peripheral Muscle ◽  
Sf 36 ◽  
Inflammatory Bowel

Abstract Introduction: Crohn’s disease (CD) is an inflammatory bowel disease, marked by exacerbations and remissions periods. Peripheral manifestations in CD may be present with the syndrome of skeletal muscle dysfunction (SMD), which is characterized by loss of muscle strength, fatigue complain, limited exercise capacity and impaired quality of life of these patients. Objective: Evaluate muscle strength, physical capacity and quality of life of patients with CD and compare them with healthy controls. Methods: 18 patients CD and 12 healthy controls matched for age and sex were involved. Peripheral muscle strength evaluated by handgrip strength of the dominant hand and respiratory muscle strength by measures of respiratory muscle strength (maximal inspiratory/expiratory pressure - MIP and MEP). Exercise capacity evaluated by Shuttle test (ST) and the quality of life by the Short-form 36 (SF-36) and by the Inflammatory Bowel Disease Questionnaire (IBDQ). Results: Patients with CD presented a lower respiratory muscle strength (MIP = -68.93 ± 26.61 vs 29.63 ± -100 cmH2O, p = 0.0013 and MEP = 81.07 ± 30.26 vs 108 ± 25.30 cmH2O, p = 0.032) and a tendency the lower peripheral muscle strength (31.72 ± 8.55 vs 39.00 ± 13.37 kgf, p = 0.09). In addition, CD patients presented worse physical capacity on the ST compared to the control group (513.7 ± 237m vs 983.0 ± 263m, p < 0.05) and worse quality of life in 7 of 8 domains of the SF-36 and in all dimensions of the IBDQ. Conclusion: Patients with CD showed muscle functional impairment and poorer quality of life compared to healthy control group. These findings suggest that the assessment and maybe interventions in the muscle function must be used in clinical practice.

scholarly journals Monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of pulmonary function evaluation in amyotrophic lateral sclerosis

2013 ◽  
Vol 71 (3) ◽  
pp. 146-152 ◽  
Author(s):  
Guilherme Fregonezi ◽  
Palomma Russelly Saldanha Araújo ◽  
Tathiana Lindemberg Ferreira Macêdo ◽  
Mario Emilio Dourado Junior ◽  
Vanessa Regiane Resqueti ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscle Strength ◽  
Early Diagnosis ◽  
Pulmonary Function ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Function Evaluation ◽  
Respiratory Muscle Strength ◽  
Respiratory Dysfunction ◽  
Lateral Sclerosis

ObjectiveIt was study the relationship between respiratory muscle strength and forced vital capacity (FVC) in patients with amyotrophic lateral sclerosis (ALS) versus healthy subjects.MethodsPulmonary function and respiratory muscle strength [maximal inspiratory (PImax), maximal expiratory (PEmax) and sniff nasal inspiratory pressure (SNIP)] were assessed in patients with ALS and healthy subjects, matched using cutoffs established in the literature for impaired pulmonary function and respiratory muscle weakness.ResultsTwenty-eight ALS patients and 28 healthy subjects were studied. We found sensitivity and specificity for PImax, PEmax and SNIP of 75/58%, 81/67% and 75/67%. The Receiver Operating Characteristic curve (ROC curve) indicated that the variables PImax, PEmax and SNIP can identify differences in respiratory muscle strength between ALS and healthy individuals at 0.89, 0.9 and 0.82, respectively. A positive correlation was recorded between FVC (%) versus SNIP, PImax and PEmax.ConclusionIn ALS, monitoring respiratory muscle strength assists in early diagnosis of respiratory dysfunction as opposed to the isolated use of FVC.

Impairment of respiratory muscle function in pulmonary hypertension

2007 ◽  
Vol 114 (2) ◽  
pp. 165-171 ◽  
Author(s):  
Hans-Joachim Kabitz ◽  
Anja Schwoerer ◽  
Hinrich-Cordt Bremer ◽  
Florian Sonntag ◽  
Stephan Walterspacher ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Muscle Strength ◽  
Muscle Function ◽  
Respiratory Muscle ◽  
World Health ◽  
Walking Distance ◽  
Respiratory Muscle Strength ◽  
Control Subjects ◽  
Respiratory Muscle Function ◽  
Health Organization

It has been suggested that impaired respiratory muscle function occurs in patients with PH (pulmonary hypertension); however, comprehensive investigations of respiratory muscle function, including the application of non-volitional tests, needed to verify impairment of respiratory muscle strength in patients with PH have not yet been performed. In the present study, respiratory muscle function was assessed in 31 patients with PH (20 females and 11 males; mean pulmonary artery pressure, 51±20 mmHg; median World Health Organization class 3.0±0.5; 25 patients with pulmonary arterial hypertension and six patients with chronic thromboembolic PH) and in 31 control subjects (20 females and 11 males) well-matched for gender, age and BMI (body mass index). A 6-min walking test was performed to determine exercise capacity. Volitionally assessed maximal inspiratory (7.5±2.1 compared with 6.2±2.8 kPa; P=0.04) and expiratory (13.3±4.2 compared with 9.9±3.4 kPa; P<0.001) mouth pressures, sniff nasal (8.3±1.9 compared with 6.6±2.2 kPa; P=0.002) and transdiaphragmatic (11.3±2.5 compared with 8.7±2.5 kPa; P<0.001) pressures, non-volitionally assessed twitch mouth (1.46±0.43 compared with 0.97±0.41 kPa; P<0.001) and transdiaphragmatic (2.08±0.55 compared with 1.47±0.72 kPa; P=0.001) pressures during bilateral anterior magnetic phrenic nerve stimulation were markedly lower in patients with PH compared with control subjects. Maximal inspiratory mouth (r=0.58, P<0.001) and sniff transdiaphragmatic (r=0.43, P=0.02) pressures were correlated with the 6-min walking distance in patients with PH. In conclusion, the present study provides strong evidence that respiratory muscle strength is reduced in patients with PH compared with well-matched control subjects. Furthermore, the 6-min walking distance is significantly linked to parameters assessing inspiratory muscle strength.

Respiratory muscle strength at rest, during and after maximal exercise in healthy subjects

2015 ◽  
Author(s):  
Letícia Zumpano Cardenas ◽  
Pauliane Vieira Santana ◽  
Mayra Caleffi Pereira ◽  
Jeferson George Ferreira ◽  
Luiz Fernando Orlandin ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Healthy Subjects ◽  
Respiratory Muscle ◽  
Maximal Exercise ◽  
Respiratory Muscle Strength

scholarly journals The Effect of Habitual Exercise on Respiratory-Muscle Function in Older Adults

2005 ◽  
Vol 13 (1) ◽  
pp. 34-44 ◽  
Author(s):  
Mark L. Watsford ◽  
Aron J. Murphy ◽  
Matthew J. Pine ◽  
Aaron J. Coutts
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Muscle Function ◽  
Respiratory Muscle ◽  
Endurance Capacity ◽  
Respiratory Muscle Strength ◽  
Exercise Participation ◽  
Inspiratory Muscles ◽  
Respiratory Muscle Function ◽  
Habitual Exercise

Older adults’ participation in habitual exercise might be affected by alterations to respiratory mechanics such as decreased respiratory-muscle strength. This reduction can cause a decrease in efficiency of the ventilatory pump, potentially compromising exercise participation. This research examined the role of habitual exercise in respiratory-muscle function and the associated implications for exercise performance. Seventy-two healthy older adults (36 men, 64.9 ± 8.6 years, 177.2 ± 8.4 cm, 82.5 ± 11.9 kg; 36 women, 64.9 ± 9.5 years, 161.7 ± 6.4 cm, 61.6 ± 9.2 kg) undertook respiratory-function and walking-performance tests. Active men and women achieved higher scores than their inactive counterparts for all tests except spirometry, where no differences were evident. The results indicate that a significant amount of the elevated fitness level might be accounted for by increased endurance capacity of the inspiratory muscles. Inactive older individuals might be at risk for inadequate respiratory-muscle strength, so interventions should be considered.

scholarly journals The Role of Inspiratory Muscle Training in Sickle Cell Anemia Related Pulmonary Damage due to Recurrent Acute Chest Syndrome Attacks

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Burcu Camcıoğlu ◽  
Meral Boşnak-Güçlü ◽  
Müşerrefe Nur Karadallı ◽  
Şahika Zeynep Akı ◽  
Gülsan Türköz-Sucak
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Respiratory Muscle ◽  
Acute Chest Syndrome ◽  
Respiratory Muscle Strength ◽  
Muscle Training ◽  
Functional Exercise ◽  
Functional Exercise Capacity

Background. The sickling of red blood cells causes a constellation of musculoskeletal, cardiovascular, and pulmonary manifestations. A 32-year-old gentleman with sickle cell anemia (SCA) had been suffering from recurrent acute chest syndrome (ACS).Aim. To examine the effects of inspiratory muscle training (IMT) on pulmonary functions, respiratory and peripheral muscle strength, functional exercise capacity, and quality of life in this patient with SCA.Methods. Functional exercise capacity was evaluated using six-minute walk test, respiratory muscle strength using mouth pressure device, hand grip strength using hand-held dynamometer, pain using Visual Analogue Scale, fatigue using Fatigue Severity Scale, dyspnea using Modified Medical Research Council Scale, and health related quality of life using European Organization for Research and Treatment of Cancer QOL measurement.Results. A significant improvement has been demonstrated in respiratory muscle strength, functional exercise capacity, pain, fatigue, dyspnea, and quality of life. There was no admission to emergency department due to acute chest syndrome in the following 12 months after commencing regular erythrocytapheresis.Conclusion. This is the first report demonstrating the beneficial effects of inspiratory muscle training on functional exercise capacity, respiratory muscle strength, pain, fatigue, dyspnea, and quality of life in a patient with recurrent ACS.

Sign in / Sign up

Export Citation Format

Share Document