scholarly journals Prevalence of pulmonary tuberculosis in young adult patients with Type 1 diabetes mellitus in India

2016 ◽  
Vol 11 ◽  
Author(s):  
Ravinder Goswami ◽  
Abilash Nair ◽  
Randeep Guleria ◽  
Devasenathipathy Kandasamy ◽  
Raju Sharma ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Pulmonary Tuberculosis ◽  
Type 1 Diabetes Mellitus ◽  
Sputum Culture ◽  
Mantoux Test ◽  
Care Hospital ◽  
History Of ◽  
Culture Positive

Background: There is limited information on prevalence of pulmonary tuberculosis (PTB) in patients with type-1- diabetes. We assessed the prevalence of PTB in patients with type-1-diabetes attending the outpatient-clinic in a tertiary-care hospital. Methods: 151 patients with type-1-diabetes were screened for PTB by clinical examination and chest-radiography. Sputum Acid-Fast Bacilli Test (AFB) and Mycobacterium tuberculosis (M.tb) culture were performed in patients with clinical and radiological features suggestive of a possibility of PTB and also in those with history of PTB in the past. Their average glycated haemoglobin (HbA1c) during preceding 2 years was assessed. Sputum culture positive patients were managed by a pulmonologist. Results: 5/151 patients had respiratory symptoms and radiographic findings suggestive of PTB. 20/151 patients were asymptomatic but had history of PTB. Four of the five symptomatic patients and 12 with past PTB were positive for sputum M.tb by culture, giving a prevalence of 10.6 % sputum culture positive in type-1-diabetes. Average HbA1c was comparable in patients with and without positive sputum culture. ESR and Mantoux test were not discriminatory in these groups. Four clinically symptomatic M.tb culture positive and four asymptomatic patients with sputum culture positive for M.tb on two occasions (6 weeks apart) were put on antitubercular treatment (ATT). Patients who were culture positive for M.tb only on one occasion were kept on a close follow up. Conclusions: Patients with type-1-diabetes mellitus in India have high prevalence of PTB. They need to be actively screened for PTB by sputum M.tb culture in order to initiate early treatment and to prevent transmission in the community.

scholarly journals Accelerated Bilateral Cataract Formation as a First Manifestation of Diabetes Mellitus

2013 ◽  
Vol 114 (4) ◽  
pp. 258-262 ◽  
Author(s):  
M. R. Manaviat ◽  
Nasim Oveisi ◽  
A. Zare-Bidoki
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Emergency Room ◽  
Type 1 Diabetes Mellitus ◽  
Cataract Formation ◽  
Bilateral Cataract ◽  
Duration Of Diabetes ◽  
History Of ◽  
New Onset

There is a proved relationship between diabetes mellitus and the cataract formation. The incidence of this is usually related to the duration of diabetes. In this manuscript we report a 15 years old female presented to the emergency room with a 4 hour history of rapid bilateral diminished vision, initially diagnosed with idiopathic cataracts, but after more laboratory evaluations revealed new-onset type 1 diabetes mellitus without ketosis.

scholarly journals Pregnancy and delivery in a patient with a 40-year history of type 1 diabetes mellitus and antiphospholipid syndrome

2018 ◽  
Vol 67 (6) ◽  
pp. 93-99
Author(s):  
Roman V. Kapustin ◽  
Natalia V. Borovik ◽  
Ekaterina V. Musina ◽  
Olga N. Arzhanova ◽  
Maria I. Yarmolinskaya ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Antiphospholipid Syndrome ◽  
Perinatal Outcomes ◽  
Increased Risk ◽  
Pregnancy And Delivery ◽  
Perinatal Center ◽  
History Of

Type 1 diabetes mellitus is a condition associated with an increased risk of adverse perinatal outcomes such as spontaneous abortions, preterm birth, placental insufficiency, congenital malformations, and perinatal mortality. Diabetes mellitus combined with cardiovascular diseases in women during pregnancy often leads to hypertensive disorders and pre-eclampsia. The severity of the microvascular diabetic complications and frequency of hypoglycemic episodes, particularly in early pregnancy, are related to the risk of pre-eclampsia. We report the case of pregnancy and delivery of a live newborn in a 42-year-old woman with type 1 diabetes mellitus, pre-existing hypertension, heritable thrombophilia, and antiphospholipid syndrome. She had a 40-year history of type 1 diabetes mellitus with well-controlled diabetic nephropathy and retinopathy. The woman had been receiving continuous subcutaneous insulin therapy for the last five years, which allowed maintaining an appropriate glycemic control during pregnancy. Multidisciplinary supervision of course of pregnancy was carried out from the pre-gravidity stage until delivery and postpartum. In spite of the severe pre-eclampsia and preterm delivery by cesarean section at 36 weeks, she and newborn could avoid the intensive unit care and discharge from perinatal center without any complications.

scholarly journals Prevalence of pulmonary tuberculosis in young adult patients with Type 1 diabetes mellitus in India

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Abilash Nair ◽  
Randeep Guleria ◽  
Devasenathipathy Kandasamy ◽  
Raju Sharma ◽  
Nikhil Tandon ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Young Adult ◽  
Pulmonary Tuberculosis ◽  
Type 1 Diabetes Mellitus ◽  
Adult Patients

scholarly journals Evaluation of Children with Type 1 Diabetes Mellitus in terms of Overweight / Obesity in Tertiary Care Hospital

2021 ◽  
Author(s):  
Eda Çelebi Bitkin ◽  
Cengiz Kara ◽  
Gülay Can Yılmaz ◽  
Jamala Mammadova ◽  
Hasan Murat Aydın
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Tertiary Care ◽  
Normal Weight ◽  
Obese Group ◽  
Care Hospital ◽  
C Peptide

Abstract Objective: Obesity was once a rare problem in Type 1 diabetes mellitus, but is a growing problem today. The aim of our study is to determine the frequency of overweight / obesity at the time of diagnosis and during follow-up in children with type 1 diabetes mellitus as well as review the conditions that may accompany. Methods: 315 patients with type 1 diabetes mellitus were retrospectively analyzed. The patients were divided into two groups according to the last examination as normal weight and overweight / obese. The two groups were compared in terms of age at diagnosis, gender, birth weight, family history, anthropometric measurements, insulin dose used and blood pressure measurements, and insulin, c-peptide, hemoglobin A1c, triglyceride, and high-density lipoprotein levels at the time of diagnosis and follow-up. Results: The prevalence of overweight / obese in all patients was 4.8% at the time of diagnosis, while it was 9.8% at the last examination. The height, weight and BMI SD scores and c-peptide levels at the time of diagnosis of the overweight / obese group were higher than those with normal weight (p <0.001 and p = 0.008, respectively). The frequency of dyslipidemia and hypertension was higher in the overweight / obese group than in the normal weight group [18.2% versus 5% (p = 0.015) and 10% versus 1.5% (p = 0.003), respectively]. Conclusion: In our study, the fact that the overweight / obese group had higher BMI and c-peptide and lower HDL values at the time of diagnosis can be evaluated as indicators that insulin resistance syndrome can accompany T1DM from the beginning (double diabetes). When determining the treatment and follow-up strategies of patients with type 1 diabetes mellitus, considering the risk of obesity and taking the necessary precautions is very important in terms of morbidity.

scholarly journals Evaluation of children with type 1 diabetes mellitus in terms of overweight/obesity in tertiary care hospital

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Eda Celebi Bitkin ◽  
Cengiz Kara ◽  
Gülay Can Yılmaz ◽  
Jamala Mammadova ◽  
Hasan Murat Aydın
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Tertiary Care ◽  
Normal Weight ◽  
Obese Group ◽  
Care Hospital ◽  
C Peptide

Abstract Objectives Obesity is a growing problem in type 1 diabetes mellitus (T1DM) today. The aim of our study is to determine the frequency of overweight/obesity at the time of diagnosis and during follow-up in children with T1DM as well as review the conditions that may accompany. Methods A total of 315 patients with T1DM were retrospectively analyzed. The patients were divided into two groups as normal weight and overweight/obese. The two groups were compared in terms of age at diagnosis, birth weight, anthropometric measurements, insulin dose used and blood pressure measurements, and insulin, c-peptide, hemoglobin A1c, triglyceride, and high-density lipoprotein levels at the time of diagnosis and follow-up. Results The height, weight and body mass index standard deviation (BMI SD) scores, and c-peptide levels at the time of diagnosis of the overweight/obese group were higher than those with normal weight (p<0.001 and p = 0.008, respectively). The frequency of dyslipidemia and hypertension was higher in the overweight/obese group than in the normal weight group [18.2 vs. 5% (p = 0.015) and 10 vs. 1.5% (p = 0.003), respectively]. Conclusions In our study, the fact that the overweight/obese group had higher BMI and c-peptide and lower HDL values at the time of diagnosis can be evaluated as indicators that insulin resistance syndrome can accompany T1DM from the beginning (double diabetes). When determining the treatment and follow-up strategies of patients with T1DM, considering the risk of obesity and taking the necessary precautions is very important in terms of morbidity.

scholarly journals Predictive Factors of Quality of Life in Adults with Long-standing Type 1 Diabetes Mellitus

2020 ◽  
Author(s):  
Ana Castellano-Guerrero ◽  
Raquel Guerrero ◽  
Desiree Ruiz-Aranda ◽  
Sofia Perea ◽  
Alfonso Pumar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Social Support ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Predictive Factors ◽  
Care Hospital ◽  
Female Patients

Abstract Background: To determine gender differences in Quality of life (QoL) perception and to identify sociodemographic, clinical and psychological characteristics associated with impaired QoL in adults with long-standing type 1 diabetes mellitus (DM1). Methods: Cross-sectional evaluation in a random cohort of DM1 adult patients from a tertiary care hospital. QoL was evaluated using translated and validated self-administered Diabetes QoL questionnaire (Es-DQoL), and results transformed into a 0-100 scale. Psychological assessment included a planned psychological interview and self-reported questionnaires (Beck Depression Inventory II, State-Trait Anxiety Inventory Form Y, Fear of hypoglycaemia Scale, Medical Outcomes Study Social Support Survey). Results: A total of 312 patients (51.6% male; 38.2 ± 12.7 years; HbA 1c 7.5 ± 1.1% (58.5 ± 14.2 mmol/mol); 20.4 ± 12.0 years of DM1) were included in the analysis. Male and female subgroups showed similar sociodemographic and diabetes-related features and comparable social support. Among female patients, higher frequency of depression (31.7% vs. 14.9%, p<0.05) and anxiety (23.2% vs. 13.0%, p<0.05) and severity of depressive and anxious symptoms were also found. Compared to male patients, female patients showed a lower perception of QoL (75 [65-85] vs. 80 [69-87], p<0.05) and scored significantly worse in subscale Diabetes-related worries (69 [50-81] vs. 75 [62-88], p<0.05). Fear of hypoglycemia and severity of depressive and anxious symptoms, as well as the presence of macrovascular complications and high frequency of glycemic excursions were predictive factors of QoL. Conclusions: Adult women with long-standing DM1 showed a worse QoL perception probably related to higher frequency of psychopathological syndromes. Exposure to glycemic excursions and depressive and anxious symptoms were identified as modifiable, QoL-related variables. Educational, technological and psychological interventions aimed at reducing glycemic variability and improving psychological status are needed in order to improve QoL in DM1 patients.

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