Integrated Treatment of Comorbid Depression and Substance Use Disorders

Eating disorders (ED) and substance use disorders (SUD) frequently co-occur but are rarely treated in a comprehensive integrated manner. This chapter elucidates the complex relationship between ED and SUD to help the treating professional create an integrated treatment plan that addresses both disorders and any other co-occurring conditions. Evidence-based treatments for each disorder are discussed, and recommendations on how to take “best practices” from both fields to formulate a treatment plan that addresses the specific needs of the patient are presented. The chapter includes case examples that demonstrate the importance of understanding the adaptive function of both disorders when developing an effective intervention.

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Integrated Treatment for Mood and Substance Use Disorders

Psychiatric Services ◽

10.1176/appi.ps.55.5.595 ◽

2004 ◽

Vol 55 (5) ◽

pp. 595-595

Author(s):

Robert E. Drake

Keyword(s):

Substance Use ◽

Substance Use Disorders ◽

Integrated Treatment

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When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field

Substance Abuse Research and Treatment ◽

10.4137/sart.s9245 ◽

2012 ◽

Vol 6 ◽

pp. SART.S9245 ◽

Cited By ~ 1

Author(s):

Linda E. Wüsthoff ◽

Helge Waal ◽

Rolf W. Gråwe

Keyword(s):

Clinical Trial ◽

Substance Use ◽

Randomized Clinical Trial ◽

Substance Use Disorders ◽

Clinical Studies ◽

Psychosocial Interventions ◽

Integrated Treatment ◽

Lessons Learned ◽

Future Research ◽

New Challenges

Research on treatments for patients with co-occurring psychiatric and substance use disorders is of core importance and at the same time highly challenging as it includes patients that are normally excluded from clinical studies. Such research may require methodological adaptations which in turn create new challenges. However, the challenges that arise in such studies are insufficiently discussed in the literature. The aim of this methodology paper is, firstly, to discuss the methodological adaptations that may be required in such research; secondly, to describe how such adaptations created new challenges in a group-randomized clinical trial on Integrated Treatment amongst patients with co-occurring psychiatric and substance use disorders. We also discuss how these challenges might be understood and highlight lessons for future research in this field. Trial registration: NCT00447733.

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Efficacy of antidepressants in substance use disorders with and without comorbid depression

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2004.09.004 ◽

2005 ◽

Vol 78 (1) ◽

pp. 1-22 ◽

Cited By ~ 151

Author(s):

Marta Torrens ◽

Francina Fonseca ◽

Gerard Mateu ◽

Magí Farré

Keyword(s):

Substance Use ◽

Substance Use Disorders ◽

Comorbid Depression

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Integrated Treatment of PTSD and Substance Use Disorders: Examination of Imaginal Exposure Length

Journal of Traumatic Stress ◽

10.1002/jts.22175 ◽

2017 ◽

Vol 30 (2) ◽

pp. 166-172 ◽

Cited By ~ 1

Author(s):

Adam C. Mills ◽

Christal L. Badour ◽

Kristina J. Korte ◽

Therese K. Killeen ◽

Aisling V. Henschel ◽

...

Keyword(s):

Substance Use ◽

Substance Use Disorders ◽

Integrated Treatment ◽

Imaginal Exposure ◽

Exposure Length

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Childhood and adolescent risk factors for comorbid depression and substance use disorders in adulthood

Addictive Behaviors ◽

10.1016/j.addbeh.2012.06.008 ◽

2012 ◽

Vol 37 (11) ◽

pp. 1240-1247 ◽

Cited By ~ 32

Author(s):

Kerry M. Green ◽

Katarzyna A. Zebrak ◽

Kate E. Fothergill ◽

Judith A. Robertson ◽

Margaret E. Ensminger

Keyword(s):

Risk Factors ◽

Substance Use ◽

Substance Use Disorders ◽

Comorbid Depression ◽

Adolescent Risk

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Co-occurring Substance Use Disorders

10.1093/med/9780190610999.003.0020 ◽

2017 ◽

Author(s):

Michael Soule ◽

Hilary S. Connery

Keyword(s):

Mental Health ◽

Substance Use ◽

Substance Use Disorders ◽

Psychotic Disorders ◽

Behavioral Therapy ◽

Contingency Management ◽

Integrated Treatment ◽

Mental Health Clinics ◽

Medication Assisted Treatment ◽

Community Mental Health Clinics

Substance use disorders are frequently comorbid with mood, anxiety, and psychotic disorders, and they commonly present in tandem in both primary care and psychiatric settings. Unfortunately, in the past, individuals with co-occurring substance use and mental health disorders would receive treatment in community mental health clinics only after their substance use disorder was “stabilized.” There has been increasing recognition that integrated treatment is necessary for these individuals to fully succeed and achieve recovery. This chapter uses a common presentation to illustrate up-to-date screening and treatment recommendations. Motivational interviewing, contingency management, cognitive–behavioral therapy, and medication-assisted treatment are explored. A discussion of the continuum of community-based services and systems challenges follows.

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Cognitive Therapy for Comorbid Depression

10.1093/oxfordhb/9780199797004.013.009 ◽

2014 ◽

Author(s):

Mark A. Whisman ◽

Daniel BE

Keyword(s):

Substance Use ◽

Anxiety Disorders ◽

Personality Disorders ◽

Cognitive Therapy ◽

Substance Use Disorders ◽

Clinical Guidelines ◽

Clinical Samples ◽

Comorbid Depression ◽

Axis Ii ◽

Axis I

Depression often co-occurs with other Axis I and Axis II psychiatric disorders. This chapter presents a model for how cognitive therapy (CT) of depression can be adapted in conceptualizing and treating the complex set of issues and problems that often accompany comorbid depression. It begins with a discussion of the prevalence of comorbidity in community and clinical samples, then review the research on comorbidity and outcome to CT for depression, followed by a model for adapting or modifying CT for patients who present with depression and a comorbid Axis I or Axis II disorder. The chapter concludes with specific clinical guidelines for treating depression that co-occurs with anxiety disorders, substance use disorders, and personality disorders.

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