Management of early onset severe preeclampsia in a tertiary hospital in india: does expectant management alter perinatal outcome?

2011 ◽  
Vol 65 (12) ◽  
pp. 535 ◽  
Author(s):  
Manisha Kumar ◽  
Usha Gupta ◽  
Namita Jain ◽  
Jyoti Meena ◽  
Abha Singh
2020 ◽  
Vol 32 (2) ◽  
pp. 73-78
Author(s):  
Kamrun Nahar ◽  
Hosna Akter ◽  
Summyia Nazmeen ◽  
Saria Tasnim

Background: Management of severe pre eclampsia remote from term remains one of the most difficult challenges in obstetric practice. Expectant management of early onset severe pre eclampsia improves neonatal outcome. Methods: A prospective case series extending over five years peiod were recorded to evaluate the maternal and perinatal outcome of expectant management of severe preeclampsia presenting between 24-34 weeks of gestation in a tertiary referral center. All women (n=160) presenting with early onset (24-34 weeks of gestation) severe preeclampsia , where both the mother and the fetus were otherwise stable. Frequent clinical and biochemical monitoring of maternal status with careful blood pressure control. Foetal surveillance included six hourly foetal heart rate monitoring, bi weekly non stress test and weekly USG evaluation. Results: Mean number of days of prolongation of gestation was 6 days ( range 1-24days). The largest prolongation of pregnancy was recorded in patients with the lowest gestational age. Conservative management was associated with a 1.63% ( 17/160) intrauterine fetal loss rate. The days of pregnancy prolongation and perinatal mortality were significantly higher among those managed at <30 weeks. Increasing gestational age correlated with a reduction of RDS ( respiratory distress syndrome). Maternal morbidities were significantly higher among those managed at < 32 weeks. But there was no maternal mortality. Conclusion: Good perinatal outcome and less risk to mother can be achieved at 30-34 weeks gestation. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 73-78


2021 ◽  
Vol 28 (1) ◽  
pp. 28-35
Author(s):  
Zohreh Tabasi ◽  
Elahe Mesdaghinia ◽  
Masoumeh Abedzadeh-Kalahroudi ◽  
Hossein Akbari ◽  
Mahsa Bandagi-Motlagh ◽  
...  

2000 ◽  
Vol 107 (10) ◽  
pp. 1258-1264 ◽  
Author(s):  
D. R. Hall ◽  
H. J. Odendaal ◽  
G. F. Kirsten ◽  
J. Smith ◽  
D. Grove

2020 ◽  
pp. 1-4
Author(s):  
Debika Biswas ◽  
Shalini Gainder ◽  
Debarshi Jana

Preeclampsia is a heterogeneous clinical syndrome which is a leading cause of maternal, fetal, and neonatal morbidity and mortality. The aim of the study evaluate the maternal and fetal outcome in women with diagnosis of early onset preeclampsia. The present study was conducted with the primary objective to study the maternal, fetal and neonatal outcome among women diagnosed with early onset of preeclampsia without severe feature and with severe features. The overall outcome in women where pregnancies were continued after giving Mgso4 therapy were also studied. This was a prospective hospital based study in which 119 pregnant women were enrolled from emergency ward (labour room) who were diagnosed to have early onset preeclampsia at less than 32 weeks of gestation. Women with early onset preeclampsia were given expectant management and the maternal and perinatal outcome in women were reviewed as per severity that is whether PE occurred with or without severe features. The maternal complications did not increase in women who received expectant management in women with PE with severe features, as well as the group which had received prophylactic Mgso4 therapy and in whom subsequently pregnancy continued for few days to weeks. The perinatal outcome was compromised because of early presentation of PE which probably causes the placental insufficiency even in women without severe features. Significant number of days gained during expectant management has an impact on the perinatal outcome which was from few days to weeks in this study.


2009 ◽  
Vol 282 (1) ◽  
pp. 23-27 ◽  
Author(s):  
El-Said Abdel-Hady ◽  
Muhammad Fawzy ◽  
Mohamed El-Negeri ◽  
Mohamed Nezar ◽  
Ahmed Ragab ◽  
...  

Author(s):  
Deepak A. V. ◽  
Reena R. P. ◽  
Deepa Anirudhan

Background: Expectant management of severe preeclampsia, remote from term is often a difficult decision. Maternal and foetal complications may occur while trying to achieve a more favourable perinatal outcome. We wanted to find out the foetal and maternal outcomes of expectant management in these women.Methods: A prospective cohort study was conducted at Government Medical College, Thrissur, India between May 2013 and April 2015. Women with severe preeclampsia remote from term, who were admitted, managed expectantly and delivered in our hospital during the study period, were recruited. The study subjects were grouped into: Group A (between 28 weeks and 31 weeks 6 days) and Group B (between 32 weeks and 33 weeks 6 days). A structured proforma was used to collect demographic and clinical details. The maternal and foetal outcomes were noted.Results: There were 4786 deliveries during the study period. Among them 76 (1.58% of total deliveries) women with severe preeclampsia between 28 weeks and 33-week 6 days gestation on expectant management were included in the study. The mean duration of expectant management was 7.92 days in group A (27 women) and 6.67 days in group B (49 women). Most women required termination of pregnancy for foetal distress (36.8%). HELLP syndrome and imminent eclampsia were the maternal complications that occurred. Perinatal loss was significantly more in Group A when compared to Group B.Conclusions: Expectant management of women with severe preeclampsia remote from term, especially between 32weeks and 33weeks 6 days, with antenatal corticosteroids and close monitoring, seems a reasonable option in developing countries.


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