scholarly journals Fetal and maternal outcome following expectant management of severe pre-eclampsia remote from term

Author(s):  
Deepak A. V. ◽  
Reena R. P. ◽  
Deepa Anirudhan

Background: Expectant management of severe preeclampsia, remote from term is often a difficult decision. Maternal and foetal complications may occur while trying to achieve a more favourable perinatal outcome. We wanted to find out the foetal and maternal outcomes of expectant management in these women.Methods: A prospective cohort study was conducted at Government Medical College, Thrissur, India between May 2013 and April 2015. Women with severe preeclampsia remote from term, who were admitted, managed expectantly and delivered in our hospital during the study period, were recruited. The study subjects were grouped into: Group A (between 28 weeks and 31 weeks 6 days) and Group B (between 32 weeks and 33 weeks 6 days). A structured proforma was used to collect demographic and clinical details. The maternal and foetal outcomes were noted.Results: There were 4786 deliveries during the study period. Among them 76 (1.58% of total deliveries) women with severe preeclampsia between 28 weeks and 33-week 6 days gestation on expectant management were included in the study. The mean duration of expectant management was 7.92 days in group A (27 women) and 6.67 days in group B (49 women). Most women required termination of pregnancy for foetal distress (36.8%). HELLP syndrome and imminent eclampsia were the maternal complications that occurred. Perinatal loss was significantly more in Group A when compared to Group B.Conclusions: Expectant management of women with severe preeclampsia remote from term, especially between 32weeks and 33weeks 6 days, with antenatal corticosteroids and close monitoring, seems a reasonable option in developing countries.

1970 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Rukshana Ahmed ◽  
Shamim Ara

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77


2017 ◽  
Vol 5 (1) ◽  
pp. 49 ◽  
Author(s):  
Vigna Sai Potula

Background: This study compares the efficacy of vacuum therapy against conventional iodine povidone dressing with respect to area and time of ulcer.Methods: This study is a randomized controlled trail which was conducted in Meenakshi Medical College hospital and research institute Enathur Kanchipuram. The number of patients selected were 50, which were divided into 2 groups, Group A which consisted of 25 and received vacuum therapy, Group B which consisted of 25 and received povidone-iodine solution.Results: This study was a 16 days study, mean area of ulcer on day 0 was 11.25 cm2 in group B, 10.89 cm2 in group A. On day 6, mean area of ulcer was 10.44 cm2 in group B, 8.98 cm2 in group A. Mean area of ulcer was 10.39 cm2 in group B, 7.66 cm2 in group A on the end of the day 16. The results show that both the groups showed decrease in the area of ulcers, but patients in group A who underwent vacuum therapy have shown greater decrease in the mean area of ulcer. The decrease in surface area of ulcer was statistically significant i.e. p=0.025. There was a greater decrease in infection in group A on 16th day compared to group A on 16th day. On day 0, 48% and 60% growth of microorganisms was observed in patients of group B and group A respectively (p=0.428). On day 16, 28% and 8% growth of microorganisms was observed in patients of group B and group A respectively (p=0.034).Conclusions: Vacuum therapy was more effective compared to conventional method of povidone-iodone solution dressing in rate of healing and time of healing.


2014 ◽  
Vol 5 (1) ◽  
pp. 10-13
Author(s):  
Sabiha Mahbub ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Shamim Ara ◽  
Abdul Alim

A cross-sectional descriptive study was performed in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008, on post mortem parathyroid glands of 60 Bangladeshi people in different age groups. A total of 207 parathyroid glands were identified in relation to posterior border of thyroid lobes and collected from those 60 cadavers. The samples were collected from the unclaimed dead bodies within 24 hours after death that were under examination in the Department of Forensic Medicine of Dhaka Medical College, Dhaka. The samples were divided into three different age groups ranging from 15 to 75 years. The three groups are group A (10-30 years), group B (31-60 years) and group C (61-90 years). From each group, 20 best prepared slides were taken for examination. The percentage volume of parenchyma (glandular portion) and stroma (fibrous part with blood vessels and fat) were estimated by the point counting technique with Zeiss-I integrating eyepiece under the light microscope at low magnification. The mean SD percentage volume of parenchyma varies 64.88 2.75 to 65.90 2.33 in group A, 56.40 12.57 to 59.10 3.87 in group B and 38.80 2.77 to 41.50 2.38 in group C. In contrast, the mean SD percentage volume of stroma varies 33.50 2.27 to 34.88 2.95 in group A, 40.30 3.83 to 41.56 4.16 in group B and 58.50 2.38 to 61.20 2.77 in group C. The percentage volume of connective tissue stroma was found to increase with increasing age with simultaneous decrease in glandular parenchyma. DOI: http://dx.doi.org/10.3329/akmmcj.v5i1.18765 Anwer Khan Modern Medical College Journal Vol. 5, No. 1: January 2014, Pages 10-13


2013 ◽  
Vol 2 (1) ◽  
pp. 21-24
Author(s):  
Hasna Hena ◽  
Rubina Qasim ◽  
MD Enayet Ullah ◽  
Shamim Ara ◽  
Dilruba Siddiqua ◽  
...  

Background: Fallopian tube is one of the vital organ for human fertility.This is where the sperm fertilizes the ovum and human life begins. Detailed  morphological knowledge is essential for proper diagnosis and management of disease of fallopian tube. Study Design: Cross Sectional descriptive type of study. Place & period of study: Department of Anatomy, Dhaka Medical College, Dhaka from July 2008 to June 2009. Materials: 120 postmortem human fallopian tubes were collected from 60 unclaimed dead bodies that were under examination in the morgue of Department of Forensic Medicine, Dhaka Medical College, Dhaka. Methods: The samples were divided into three age groups: Group-A (10-13 years), Group-B (14-45 years) and Group-C (46-50 years). Results: The mean(±SD) number of fimbriae of the right & left Fallopian tubes were 21.20(±3.63) and 21.00(±4.00) in group A, 21.71(±2.13) and 21.53(±2.07) in group B and 20.90(±3.48) and 21.20± 2.30 in group C respectively.The highest mean number was found in group B and lowest mean number was in group A. The mean difference in number of fimbria of right and left Fallopian tube between Group-A, Group-B and Group-C were statistically not significant. Conclusion:In this study, the number of fimbriae does not vary in between right and left fallopian tubes, in any age group.DOI: http://dx.doi.org/10.3329/updcj.v2i1.13956 Update Dent. Coll. j: 2012; 2 (1): 21-24


2016 ◽  
Vol 44 (1) ◽  
pp. 8-10
Author(s):  
Hosna Ara Perven ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Fatema Johora ◽  
Halima Afroz ◽  
...  

This cross sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from January to December 2009, to determine the proportion of cortex and medulla of the ovary in di_erent age group of Bangladeshi women. This study was based on collection of 140 ovaries of 70 unclaimed female dead bodies from the morgue of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including A (10-13 years), B (14-45 years) & C (46-52 years). Histological slides were prepared by using routine haematoxylin and eosin stain. Ten best prepared histological slides from each age group were examined to determine the thickness of the cortex and medulla & proportion of the thickness of the cortex and the medulla of the ovary were expressed in percentages. The mean proportion of the cortex and the medulla of the right ovary were found 80.83±0.58% and 19.17±0.58% in group A, 86.95±1.14% and 13.05±1.14% in group B, 70.53±1.53% and 29.47±1.53% in group C respectively. The mean proportion of the cortex and the medulla of the left ovary were found 80.63±0.58% and 19.37±0.58% in group A, 86.78±1.14% and 13.22±1.14% in group B, 70.41±1.50% and 29.59±1.50% in group C respectively. The difference in mean proportion of the cortex and the medulla was not signi_cant in between the ovaries. However, the difference in mean proportion of the cortex and the medulla of the ovary between group A & group B, group A & group C and group B & group C were statistically significant.Bangladesh Med J. 2015 Jan; 44 (1): 8-10


2016 ◽  
Vol 30 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Sankar Kumar Basak ◽  
Kohinoor Begum ◽  
Maliha Rashid ◽  
Nahid Yasmin ◽  
Hasina Begum

Objective(s): To assess the association between the haematocrit value and severity of preeclampsia.Materials & Methods: This cross sectional study was conducted in the department of Obstetrics & Gynaecology of Dhaka Medical College Hospital, Dhaka during the period of January 2012 to December 2013. Total of 100 patients were studied and they were divided into two groups – group-A and group-B. Fifty preeclamptic patients were included in the group-A and 50 normal pregnant women were included in the group-B.Results: Majority of preeclamptic women (68%) and normal pregnant women (76%) were in the age group of 20-30 years with the mean ages of group-A and group-B subjects were 26.50±5.71 and 26.26±4.91 years respectively. Eighty six percent of group-A and 70% of group-B women were of lower socioeconomic status. Majority of the study subjects (74% of group-A and 80% of group-B) were housewife. More than half (54%) of the preeclamptic women were primigravid and 60% of normal pregnant women were multigravid. Among the preeclamptic subjects 16 (32%) had mild hypertension (DBP<110mmHg) and 34 (68%) had severe hypertension (DBP ? 110 mmHg). Out of 50 preeclamptic subjects 45 (90%) had severe proteinuria (+++) and only 5 (10%) had moderate (++) proteinuria.The mean haematocrit value of preeclamptic patients was 34.881±3.03 and that of normal pregnant women was 31.94±1.2. It was statistically significant (P value 0.001). The mean haematocrit value of normal pregnant, mild and severe preeclamptic women were 31.94±1.2, 33.31±2.57 and 35.62±2.95 respectively. It was also statistically significant (P value 0.001).Conclusion: This study shows that haematocrit value of preeclamptic patients is significantly higher compared to that of the normal pregnant women (P<0.05). There is a strong association of increasead haematocrit and preeclampsia.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 80-85


Mediscope ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Dilruba Siddiqua ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Fatema Johora ◽  
Hasna Hena ◽  
Sunjida Shahriah ◽  
...  

Background: The human adrenal gland shows a distinct proportion of two histological zones, named the cortex and the medulla, from outer inwards, in its histological appearance with differences in its cellular components and functions. Objective: The present study aims to see the variation in the proportion of the cortex and the medulla of the adrenal glands with age in a Bangladeshi population. Methods: A cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2008 to June 2009, based on collection of 140 postmortem human adrenal glands from 70 unclaimed dead bodies, in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including A (11-20 years), B (21-30 years), C (31-40 years) & D (41-60 years). Histological slides were prepared by using routine haematoxylin and eosin stain (H & E). Five best prepared slides from each group were examined under light compound microscope with low magnification. The thickness of adrenal cortex and medulla were measured by using ocular and stage micrometer and then converted into percentage volume. Results: The mean volume of the right adrenal cortex were found 83.64±3.71% in group A, 83.90±1.75% in group B, 83.74±5.78% in group C, 84.80±3.82% in group D, while the mean volume of the corresponding medulla were found 18.16±3.23% in group A, 15.70±2.71% in group B, 16.26±3.97% in group C, 16.20±4.04% in group D. The mean volume of the left adrenal cortex were found 84.64±3.49%, 84.90±1.75%, 84.20±3.40%, 85.44±2.66% in group A, B, C and D respectively, while the mean volume of the corresponding medulla were found 17.26±3.84%, 17.00±2.37%, 16.00±3.20% and 14.36±2.33% in group A, B, C and D respectively. The differences among the groups were not statistically significant. Conclusion: No difference was found in the proportion of the cortex and the medulla of adrenal gland in different age-groups. Mediscope Vol. 8, No. 1: January 2021, Page 1-6


2013 ◽  
Vol 22 (1) ◽  
pp. 34-38
Author(s):  
Sabiha Mahbub ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Abdul Alim ◽  
Rukshana Ahmed ◽  
Shamim Ara

Context: A cross-sectional descriptive type of study was designed to find out the difference in weight of the parathyroid glands of Bangladeshi people in relation to age and sex and to compare with the previous studies. Methods: This study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008. The study was performed on 207 post mortem human parathyroid glands collected from 60 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age-groups including group A (10-30 years), group B (31-60 years) & group C (61-90 years) and the weight of the parathyroids were measured and recorded. Results: The mean weight of the right superior parathyroid glands were 13.43±13.77 mg in group A, 13.86±19.15 mg in group B and 9.25±5.12 mg in group C in males and 16.00±6.69 mg in group A and 8.57±5.97 mg in group B in females respectively. The mean weight of the right inferior parathyroids were 17.78±13.94 mg, 16.75±15.67 mg and 23.00±11.53 mg in group A, B and C respectively in males and 26.00±4.18 mg in group A and 15.20±4.32 mg in group B in females. The mean weight of the left superior parathyroid glands were 13.63±6.08 mg in group A, 10.58±7.57 mg in group B and 11.00±3.74 mg in group C in males and 16.20±7.89 mg in group A and 8.29±5.47 mg in group B in females respectively. The mean weight of the left inferior parathyroid gland was 26.11±24.29 mg, 15.81±10.28 mg and 25.25±25.28 mg in group A, B and C respectively in males and 32.25±13.82 mg in group A and 13.29±5.41 mg in group B in females. No difference was found in the weight of superior parathyroid glands at right side between sexes and age groups excepting in superior and inferior parathyroid glands at left side between group A & B (p<0.05). DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15603 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 34-38


2013 ◽  
Vol 22 (1) ◽  
pp. 16-18
Author(s):  
Gul Newaz Begum ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Sunjida Shahriah ◽  
Khandaker Abu Rayhan ◽  
Hosna Ara Perven

Context: A Cross-sectional, descriptive type of study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2005 to June 2006, to see the variation in the size of the stomach with age in Bangladeshi people. Methods: The study was performed on 60 post mortem human stomach collected from unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including group A (2-16 years), group B (17-22 years) and group C (23-65 years). The length and breadth of each stomach were measured by using a measuring tape. Results: The mean length of the stomach were found 12.18±1.77 cm in group A, 17.74±1.95 cm in group B, and 25.31±1.63 cm in group C. The mean breadth of the stomach were found 6.81±0.40 cm, 8.26±0.57 cm and 9.54±0.45 cm in group A, B and C respectively. The differences between age groups were statistically significant (P<0.001). Conclusion: The length and breadth of the human stomach increase with age. DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15598 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 16-18


2020 ◽  
Vol 7 (10) ◽  
pp. 3305
Author(s):  
Goutam K. Chowdegowda ◽  
Satya V. Arya ◽  
Ashok K. Sharma ◽  
Dheer Singh Kalwaniya ◽  
Jaspreet Singh Bajwa

Background: If properly used in appendicitis, antibiotics can reduce the rate of infection by 50%. The use of post-operative antibiotics for preventing infective complications in non-perforated cases is still controversial.Methods: A randomised prospective study was conducted in the Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi with patients who presented acute appendicitis. A minimum number of 30 patients each in group A (pre-operative and post-operative antibiotics) and group B (only pre-operative antibiotics) were evaluated for 18 months, from January 2018 to June 2019.Results: The mean age of group A is 29.9±15.16 years and in group B is 25.97±9.470 years (p value=0.122, insignificant). There was male preponderance. The seroma formation in both the groups was 10.00% and no patients developed intra-abdominal abscess. The incidence of local site oedema was 10% in both the groups A and B and their p value is insignificant. In both the groups A and B, 10% of the people developed pus discharge from the stitch line and the p value is insignificant. In group A, 6.67% of the patients and in group B 10.00% of the patients developed stitch line inflammatory changes and the p value insignificant. In group A, 13.3% and in group B, 10.00% of the patients developed fever and their p value is 1. The mean length of hospital in case 1.23±0.5 days (group A) and is 1.17±0.45 days (group B) (p value=0.508).Conclusions: Hence we can conclude that a well-chosen and adequately-timed pre-operative antibiotics are adequate in preventing post-operative complications and post-operative antibiotics do not affect the same.


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