scholarly journals Autopsy findings and clinical diagnoses: A retrospective analysis of 641 cases in Greece

2013 ◽  
Vol 59 (2) ◽  
pp. 157 ◽  
Author(s):  
SA Papadodima ◽  
CI Evaggelakos ◽  
IN Sergentanis ◽  
CA Spiliopoulou
2005 ◽  
Vol 129 (2) ◽  
pp. 210-214
Author(s):  
Chaido Spiliopoulou ◽  
Stavroula Papadodima ◽  
Nikolaos Kotakidis ◽  
Antonios Koutselinis

Abstract Context.—Despite medical and technologic advances, clinicians may misdiagnose a patient's situation and the cause of death. Autopsy may be valuable in uncovering the most frequent diagnostic pitfalls and helping clinicians to learn and to develop the medical art and science. Objective.—To compare the clinical diagnoses with postmortem findings and evaluate the frequency of diagnostic errors assessed by autopsies. Design.—Retrospective analysis of the protocols of 252 consecutive cases of adult patients autopsied in the Department of Forensic Medicine and Toxicology of Athens Medical School during the period 1999–2003. The outcome measures included concordance between diagnosis before death and at autopsy, sex, age, and length of hospitalization of the patient. Results.—In 73 cases (29%), the autopsy findings confirmed the clinical diagnosis and the cause of death suggested by the clinicians. In 45 cases (19%), the clinical diagnosis and the cause of death suggested by the clinicians were discordant with the autopsy findings. In 105 cases (42%), the autopsy requests did not include any suggestion about the cause of the patient's death. In 7 cases (3%), several diagnoses were suggested by the clinicians, and in 16 cases (6%), the comparison between clinical and postmortem diagnosis was not possible. The most frequently misdiagnosed diseases were coronary disease and pulmonary embolism. Conclusions.—It is concluded from this study that autopsies may reveal unexpected findings that are of critical importance and that a continued emphasis on autopsy evaluation is necessary to improve the quality of patient care.


2012 ◽  
Vol 59 (13) ◽  
pp. E929
Author(s):  
Edimar Alcides Bocchi ◽  
Thiago Ninck Valette ◽  
Silvia Moreira Ayub-Ferreira ◽  
Victor Issa ◽  
Luiz Alberto Benvenuti ◽  
...  

2006 ◽  
Vol 7 (5) ◽  
pp. 501
Author(s):  
Marta P Cardoso ◽  
Dafne C Bourguignon ◽  
M??rcio M Gomes ◽  
Paulo HN Saldiva ◽  
Cr??sio R Pereira ◽  
...  

2012 ◽  
Vol 40 (3) ◽  
pp. 842-846 ◽  
Author(s):  
Eva Tejerina ◽  
Andrés Esteban ◽  
Pilar Fernández-Segoviano ◽  
José María Rodríguez-Barbero ◽  
Federico Gordo ◽  
...  

2019 ◽  
Vol 9 (1-2) ◽  
pp. 44-50
Author(s):  
Lindsey T Ellis ◽  
Madeleine Opsahl ◽  
Deiter J. Duff ◽  
Carl C. Stacy

Introduction: Drowning deaths present a challenge for forensic pathologists, because the autopsy findings may occur in many nondrowning scenarios. Previous studies have attempted to identify patterns in organ weights that may be specific for drowning. The drowning index (DI) has been defined as the weight ratio of the lungs and pleural effusion fluid to the spleen. Studies have suggested DI may be useful in confirming drowning as the cause of death. No studies have yet compared autopsy findings in drownings to those in drug-related deaths, in spite of their qualitative similarities. Materials and Methods: We compared the lung and pleural effusion weight, spleen weight, and DI from 536 autopsies ruled drowning, opioid, or multidrug intoxication, or hanging in Columbia, Missouri, from 2011 to 2016. Results: Opioid overdoses result in heavier lungs and spleens than drownings, multidrug overdoses, or hangings. There is no DI value at which a death can be definitively ascribed to drowning. The median DI was significantly higher in drownings than in opioid intoxications, multidrug intoxications, or hangings ( P < .0001; P = .001; P = .005). However, very few drowning cases (13.33%) had a DI >14.1. Additionally, many opioid and multidrug overdoses had a DI >14.1. The highest calculated DI value (DI = 33) was associated with multidrug intoxication. Conclusion: In our opinion, the DI has little, if any, utility in distinguishing between drowning and drug-related deaths.


PEDIATRICS ◽  
1993 ◽  
Vol 92 (2) ◽  
pp. 248-251
Author(s):  
Joseph J. Stambouly ◽  
Ellen Kahn ◽  
Robert A. Boxer

Study objective. To examine the correlation between clinical diagnoses and autopsy findings in children who die in the pediatric intensive care unit (PICU). Design. Retrospective chart review. Setting. PICU of a university-affiliated hospital. Patients. A consecutive sample of patients who died in the PICU and had autopsies performed. Measurements and main results. Of 193 patients who died during the 7½year study period, 50 (6%) had autopsies performed. The mean age was 34.7 months (range 15 hours to 17 years), and the mean length of stay in the PICU was 12.2 days (range 2 hours to 60 days). Major admitting diagnoses included postoperative cardiac surgery (19), nonoperative cardiac disease (7), hematologic/malignant disorder (5), and acquired immunodeficiency syndrome (5). There were 5 cases (10%) where autopsy revealed a major finding that, if known prior to death, would have altered clinical management and might have resulted in cure or prolonged survival. In another 9 patients (18%) the autopsy revealed major findings that, if known prior to death, would not have altered management. Eight of these findings related to the cause of death and 2 of them involved the basic disease. There was no correlation between new findings and either patient age or length of stay in the PICU. Conclusions. Despite modern diagnostic techniques, the autopsy continues to reveal valuable and unsuspected information.


2006 ◽  
Vol 7 (5) ◽  
pp. 423-427 ◽  
Author(s):  
Marta P. Cardoso ◽  
Dafne C. Bourguignon ◽  
M??rcio M. Gomes ◽  
Paulo H. N. Saldiva ◽  
Cr??sio R. Pereira ◽  
...  

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