scholarly journals Rising trends of HCV infection over a period of 4 years among blood donors in central India: A retrospective study

2013 ◽  
Vol 3 (4) ◽  
pp. 240 ◽  
Author(s):  
Alok Kumar ◽  
Satish Sharma ◽  
Narayan Ingole ◽  
Nitin Gangane
Keyword(s):  
Retrospective Study ◽  
Blood Donors ◽  
Central India ◽  
Hcv Infection

scholarly journals Seroprevalence of Hepatitis C Virus Infection among Blood Donors at Madhya Pradesh, India: A Retrospective Study

2019 ◽  
pp. 1-8
Author(s):  
Prakriti Gupta ◽  
Dharmesh Chandra Sharma ◽  
Umesh Chandra Yadav ◽  
Jyoti Bindal ◽  
K. K. Pandey
Keyword(s):  
Hepatitis C Virus ◽  
Retrospective Study ◽  
Hepatitis C ◽  
Blood Donors ◽  
Blood Donation ◽  
Madhya Pradesh ◽  
Hcv Infection ◽  
Chi Square ◽  
Significant Difference ◽  
Blood Banks

Background: Viral hepatitis is a global health problem with 170 million Hepatitis C Virus (HCV) carriers worldwide, and 12-13 million HCV carriers in India. Unscreened blood and components play a significant role in transmission of HCV apart from reuse of injection needles, unsterilized surgical equipments and vertical transmission from mother to child.  Unsafe blood transfusion not only poses risk to patients, causing significant morbidity and mortality, but also adds to the economical burden on healthcare system. Aims and Objectives: Aim of this study is to estimate the seroprevalence of HCV infection among the voluntary and relative donors over a period of 7 years at blood banks of Madhya Pradesh with collaboration of Madhya Pradesh State AIDS control Society (MPSACS) Bhopal, India from 2011 to 2017. Materials and Methods: This is a retrospective study of blood donation at blood banks, of Madhya Pradesh, India.  Blood units were screened for TTIs from January 2011 To December 2017. HIV, HCV and HBV tests were done by ELISA. Data of HCV was collected and compared statistically by frequency distribution and percentage proportion. Chi Square (χ 2) test was used to determine the significant difference statistically. Results: The mean age of donors was 32.4 2 ± 8.63 years. Major contribution was from male donors (93.8%). Majority of donation was done voluntarily (87.3 %).  Out of the total 1,876,219 donors tested for TTIs over 7 years, 1980 (0.11%) were positive to anti HCV (p=.000001). Conclusion: The prevalence of HCV infection was 0.11% among blood donors of Madhya Pradesh, with geographic variation among districts. Aiming to provide safe blood to the patients, prevention of transmission of HCV by proper donor counseling and screening of the unit is required.

ABO and Rhesus (D) Blood Group Distribution among Blood Donors in Rural South Haryana (Mewat-Region): A 5 Years Retrospective Study

2018 ◽  
Vol 4 (3) ◽  
Author(s):  
Sudheer Singh ◽  
Shailesh Kumar Mishra ◽  
Shivani Kalhan ◽  
Puja Sharma ◽  
Rahul N Satarkar ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Blood Group ◽  
Blood Donors ◽  
Rural South ◽  
Group Distribution

scholarly journals Seroepidemiology of Hepatitis B and C Virus Infections: A Five-Year Retrospective Study Among Blood Donors in Saboba District in the Northern Region of Ghana

2021 ◽  
Author(s):  
Abel Makija Nlankpe ◽  
Patrick Kwesi Owiafi ◽  
David Adedia ◽  
Jacob Nabei Nignan ◽  
Precious Kwablah Kwadzokpui
Keyword(s):  
Retrospective Study ◽  
Hepatitis B ◽  
Blood Donors ◽  
Adult Population ◽  
Public Health Education ◽  
Northern Region ◽  
Female Group ◽  
Seroprevalence Rate ◽  
Virus Infections ◽  
Hcv Coinfection

Abstract Background and Objectives: Chronic hepatitis B and C infections are capable of progressing to liver cirrhosis and hepatocellular carcinoma. Globally, it has been estimated that over 2 billion and 170 million people are living with hepatitis B and C infections, respectively. Ghana remains one of the highly endemic countries challenged by continues spread of these viral agents in Africa. This study aimed to determine the seroprevalence and trend of Hepatitis B and C coinfections among blood donors in Saboba District of the Northern Region of Ghana. Methods: A five-year hospital based retrospective study was carried out among 8,605 blood donors comprising 8517 males and 88 females using data on blood donors from Saboba Assemblies of God Hospital located in the Saboba District in the Northern Region of Ghana from 2013 to 2017. Blood bank records on HBV and HCV potential blood donors who visited the hospital to donate blood was retrieved. Donor demographic details, i.e. age and gender were also recovered. Donors who were registered to the hospital but were not residents of the Northern Region were excluded from the study. Donors with incomplete records were also excluded from the study. The data was managed using Microsoft Excel spreadsheet 2016 and analysed using GraphPad Prism statistical software. Results: The overall prevalence of asymptomatic viral hepatitis B and C infection in the general adult population was 9.59% and 12.71%, respectively, with an HBV/HCV coinfection rate of 2.23%. The number of donors generally declined with advancement in years from 2038 (23.68%) since 2013 to as low as 1169 (13.59%) in 2016, except for 2017 where a sharp increase of 1926 (22.38%) was observed. The first and second highest proportions of donors fell within the age categories of 20-29 [51.53% (4434)] and 30-39 [32.90% (2831)]. Seroprevalence rate of HBV, HCV and HBV/HCV coinfection rates were generally higher among the female group than observed among the male category. The year-to-year variation in HBV, HCV and HBV/HCV infection was statistically significant. The highest year-to-year HBV seropositivity rate was 11.48% in the year 2013, while that for HCV and HBV/HCV coinfection was 16.24% and 5.85% respectively both documented in the year 2014. HBV and HBV/HCV coinfection rate was highest among donors aged <20 years old, while HCV seroprevalence was highest among donors aged 50-59 years old. Conclusion: Seroprevalence of HBV and HCV among donors in the Saboba District of the Northern Region of Ghana is endemic. The HBV/HCV coinfections rate also raises serious concern owing to its high prevalence rate among the younger age. Intensive public health education coupled with mobile screening and mass vaccination of seronegative individuals is advised so as to help curb further spread of the infection and in effect help safeguard the health status of potential donors in the district.

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