Extranodal diffuse large B-cell lymphoma: Experience from a tertiary care oncology center in South India

2014 ◽  
Vol 3 (4) ◽  
pp. 276
Author(s):  
Vishwanath Sathyanarayanan ◽  
TM Suresh ◽  
K.Govind Babu ◽  
Suresh Babu ◽  
LinuAbraham Jacob ◽  
...  
Keyword(s):  
B Cell ◽  
South India ◽  
Cell Lymphoma ◽  
Tertiary Care ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Oncology Center ◽  
Large B Cell

scholarly journals Diffuse large B-cell lymphoma in elderly: Experience from a tertiary care oncology center in South India

2017 ◽  
Vol 06 (02) ◽  
pp. 072-074
Author(s):  
K.N. Lokesh ◽  
M.C. Suresh Babu ◽  
K.C. Lakshmaiah ◽  
K. Govind Babu ◽  
Smitha C. Saldanha ◽  
...  
Keyword(s):  
B Cell ◽  
Response Rate ◽  
Cell Lymphoma ◽  
Tertiary Care ◽  
B Cell Lymphoma ◽  
Clinical Staging ◽  
Intermediate Risk ◽  
Large B Cell Lymphoma ◽  
Oncology Center ◽  
Large B Cell

Abstract Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most frequent non-Hodgkins lymphoma in the elderly. With the rising proportion of older persons in India, it is important to study current patterns and management of this disease, given that data in this regard are scarce in Indian settings. The aim of this study was to document the clinical features of DLBCL among elderly patients and their outcome over 7 years at a tertiary care oncology center. Materials and Methods: This was a retrospective records review of 119 DLBCL cases between January 2007 and January 2015 aged 60 years and above done at Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India. Clinical staging was done according to Ann Arbor staging as modified by Cotswold's and International Prognostic Index (IPI) calculated. Results: The mean age was 69.54 years (±5.44) with male: female ratio of 1.52:1. B symptoms were seen in 33% of patients. Thirty-six percent of the patients had stage II disease. The advanced stage was seen in 12% and bulky disease in 9.5%. Bone marrow was involved in 12%. The most common extranodal site was the head and neck region. The distribution according to the IPI was as follows: Low risk 38 (31.93%), low-intermediate risk 53 (44.54%), high-intermediate risk 20 (16.80%), and high risk 8 (6.72%). Among 119 patients, 98 (64.7%) received treatment with either combination of rituximab, cyclophosphamide, adriamycin, vincristine, epirubicin, and prednisolone. Overall response rate was 63.26% with a complete response rate of 38.77%. The overall survival ranged from 2 to 123 months with the median being 9.5 months. Conclusion: In elderly, DLBCL is common in seventh decade and most of them present in an early stage and low IPI. The incorporation of rituximab to anthracycline based chemotherapy shows a significant improvement in survival in elderly DLBCL.

Diffuse large B-cell lymphoma: experience from a tertiary care center in north India

2009 ◽  
Vol 27 (2) ◽  
pp. 310-318 ◽  
Author(s):  
Rohan Khera ◽  
Snigdha Jain ◽  
Lalit Kumar ◽  
S. Thulkar ◽  
M. Vijayraghwan ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
Care Center ◽  
Tertiary Care ◽  
B Cell Lymphoma ◽  
North India ◽  
Tertiary Care Center ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Diffuse large B-cell lymphoma: A retrospective study from a regional care center in South India

2018 ◽  
Vol 55 (1) ◽  
pp. 66 ◽  
Author(s):  
SuparnaAjit Rao ◽  
SureshMC Babu ◽  
Sunny Garg ◽  
GovindaBabu Kanakasetty ◽  
LakshmaiahChinnagiriyappa Kuntegowdanahalli ◽  
...  
Keyword(s):  
Retrospective Study ◽  
B Cell ◽  
South India ◽  
Cell Lymphoma ◽  
Care Center ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Primary Breast Diffuse Large B Cell Lymphoma – Report of 6 Cases from South India with Review of Literature

2013 ◽  
Vol 4 (4) ◽  
pp. 368-373 ◽  
Author(s):  
K. N. Lokesh ◽  
Vishwanath Sathyanarayanan ◽  
K. C. Lakshmaiah ◽  
T. M. Suresh ◽  
K. Govinda Babu ◽  
...  
Keyword(s):  
B Cell ◽  
South India ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Review Of Literature ◽  
Large B Cell Lymphoma ◽  
Large B Cell
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