scholarly journals Efficacy of acoustic radiation force impulse elastography in differentiation of benign and malignant lymph nodes

2017 ◽  
Vol 03 (02) ◽  
pp. 106-110 ◽  
Author(s):  
Rashmi Sudhir ◽  
M. V. T. Krishna Mohan ◽  
Bogala Shilpa ◽  
Veeraiah K. Chaudhary
Keyword(s):  
Lymph Nodes ◽  
Operating Characteristic ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Tissue Imaging ◽  
Arfi Elastography ◽  
The Mean ◽  
Malignant Lymph Nodes

Abstract Aims and Objectives: Aim of this study was to assess the clinical usefulness of Acoustic Radiation Force Impulse (ARFI) elastography imaging in differentiating benign and malignant/metastatic superficial nodes. Methods and Materials: ARFI elastography (Siemens Medical Solutions, Mountain View, CA) using Virtual touch Tissue Imaging (VTI) technique was performed and Shear wave velocity (m/sec) was measured in 85 patients (mean age, 49 years; range, 16–72 years) with 126 lymph nodes (96 axillary, 21 cervical and 9 inguinal nodes) which were biopsied and histo-pathologically correlated. Results: Of 126 nodes, 71 were benign (64 reactive and 7 koch's) and 55 were malignant (40 metastases and 15 lymphoma). The mean ARFI value of malignant nodes ±SD (4.42 ± 2.60) were significantly higher than the benign nodes (1.76 ± 0.44), with P <0.001. With the use of Receiver Operating Characteristic (ROC) curve, the cut off SWV was estimated to be 2.45m/s with sensitivity of 83.6%, specificity of 91%, and accuracy of 93.7 % while the conventional US based short axis diameter (SAD) measurement with cut off value of 10mm, showed the sensitivity of 62 %, specificity of 87% and accuracy of 87%. Conclusion: Acoustic radiation force impulse elastography is feasible for superficial lymph nodes and provides quantitative elasticity measurements, which may complement B-mode ultrasound and potentially improve the differentiation of benign and malignant/metastatic lymph nodes.

scholarly journals Role of Ultrasound Acoustic Radiation Force Impulse in Differentiating Benign from Malignant Superficial Lymph Nodes

2020 ◽  
Vol 10 ◽  
pp. 18
Author(s):  
Reettika Chanda ◽  
Madhavi Kandagaddala ◽  
Vinu Moses ◽  
Elanthenral Sigamani ◽  
Shyamkumar Nidugala Keshava ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Diagnostic Performance ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Area Ratio ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
The Mean ◽  
Malignant Lymph Nodes ◽  
Arfi Imaging

Objective: The purpose of this study was to evaluate the diagnostic performance of acoustic radiation force impulse (ARFI) imaging in differentiating benign from malignant peripheral lymphadenopathy. Materials and Methods: This was a prospective study approved by the Institutional Review Board with financial grant for the same. Ultrasound and ARFI imaging of peripheral lymph nodes were performed and correlated with pathological results, which were used as the reference standard. The virtual touch tissue imaging and virtual touch tissue quantification parameters of ARFI were analyzed in 86 lymph nodes, of which 78 were included in the study. Using receiver operating characteristic curve analysis, the diagnostic usefulness of ARFI values were evaluated with respect to their sensitivity, specificity, and area under the curve. Results: The mean area ratio of benign lymph nodes was 0.88 (±0.2) and that of malignant lymph nodes was 1.17 (±0.14). The mean shear wave velocities (SWV) of benign and malignant lymph nodes were 2.02 m/s (±0.94) and 3.7 m/s (±2.27), respectively. The sensitivity and specificity of virtual touch imaging area ratio in differentiating benign from malignant lymph nodes was 97% and 77%, of SWV was 71% and 70%, and of SWV ratio was 68% and 79%, respectively. Conclusion: As ARFI was found to have a superior diagnostic performance over conventional ultrasound and color Doppler in the characterization of lymph nodes, we recommend its routine use in differentiating benign from malignant nodes.

Acoustic radiation force impulse (ARFI) elastography to asses maternal and foetal structures in pregnant ewes

2018 ◽  
Vol 54 (3) ◽  
pp. 498-505 ◽  
Author(s):  
Priscila D. A. Silva ◽  
Ricardo Andrés R. Uscategui ◽  
Victor J. C. Santos ◽  
Augusto R. Taira ◽  
Renata S. G. Mariano ◽  
...  
Keyword(s):  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Arfi Elastography

scholarly journals Acoustic Radiation Force Impulse (ARFI) Elastography in Autoimmune and Cholestatic Liver Diseases

2019 ◽  
Vol 18 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Ruediger S. Goertz ◽  
Luise GaBmann ◽  
Deike Strobel ◽  
Dane Wildner ◽  
Barbara Schellhaas ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Arfi Elastography

Performance of Acoustic Radiation Force Impulse Elastography for Staging Liver Fibrosis in Patients With Chronic Hepatitis C After Viral Eradication

2019 ◽  
Vol 70 (1) ◽  
pp. 114-122 ◽  
Author(s):  
Sheng-Hung Chen ◽  
Hsueh-Chou Lai ◽  
I-Ping Chiang ◽  
Wen-Pang Su ◽  
Chia-Hsin Lin ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Chronic Hepatitis C ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Viral Eradication ◽  
Arfi Elastography

Abstract Background Data on noninvasive liver fibrosis staging after viral eradication are unclear. This histology-based study validated the performance of liver stiffness (LS) measurements after viral eradication. Methods Consecutive participants with chronic hepatitis C (CHC) who received concomitant LS measurements through acoustic radiation force impulse (ARFI) elastography and percutaneous liver biopsy were prospectively screened and analyzed. Results Of the 644 patients, 521 (80.9%) underwent a biopsy at treatment baseline, and the remaining 123 (19.1%) underwent a biopsy at 3 years (median; interquartile range, 0.1) after the sustained virological response (SVR) to pegylated interferon–based and direct-acting antiviral treatments. The proportions of histological fibrosis stages did not differ significantly between the pretreatment and post-SVR groups (P = .0615). However, the LS values differed significantly (P &lt; .0001). The median LS values (presented as shear wave velocities in meters per second) were 1.51 (0.92) for the pretreatment group and 1.22 (0.77) for the post-SVR group. The cutoffs (areas under the receiver operating characteristic curve, obtained using the bootstrap method) to dichotomize between METAVIR fibrosis stage F1 versus stages F2–F4, F1–F2 versus F3–F4, and F1–F3 versus F4 were 1.47 (0.8333, 95% confidence interval [CI] 0.7981–0.8663), 1.81 (0.8763, 95% CI 0.8376–0.9107), and 1.86 (0.8811, 95% CI 0.8378–0.9179) in the pretreatment group, respectively, and 1.22 (0.7872, 95% CI 0.7001–0.8624), 1.59 (0.8808, 95% CI 0.8034–0.9422), and 1.75 (0.9018, 95% CI 0.8201–0.9644) in the post-SVR group, respectively. Conclusions The performance of LS measurements through ARFI elastography is promising to determine the liver fibrosis stage on necroinflammation-resolved histology in CHC after viral eradication.

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