scholarly journals Indian contribution toward biomedical research and development in COVID-19: A systematic review

2021 ◽  
Vol 53 (1) ◽  
pp. 63
Author(s):  
Bikash Medhi ◽  
Hardeep Kaur ◽  
Manpreet Kaur ◽  
Anusuya Bhattacharyya ◽  
Manisha Prajapat ◽  
...  
Keyword(s):  
Systematic Review ◽  
Research And Development ◽  
Biomedical Research ◽  
Indian Contribution

scholarly journals Comparison of blockchain platforms: a systematic review and healthcare examples

2019 ◽  
Vol 26 (5) ◽  
pp. 462-478 ◽  
Author(s):  
Tsung-Ting Kuo ◽  
Hugo Zavaleta Rojas ◽  
Lucila Ohno-Machado
Keyword(s):  
Systematic Review ◽  
Biomedical Research ◽  
Health Informatics ◽  
Clinical Informatics ◽  
Healthcare Applications ◽  
Software Engineers ◽  
Key Features ◽  
Technical Features ◽  
Meta Analyses ◽  
Selection Of

Abstract Objectives To introduce healthcare or biomedical blockchain applications and their underlying blockchain platforms, compare popular blockchain platforms using a systematic review method, and provide a reference for selection of a suitable blockchain platform given requirements and technical features that are common in healthcare and biomedical research applications. Target audience Healthcare or clinical informatics researchers and software engineers who would like to learn about the important technical features of different blockchain platforms to design and implement blockchain-based health informatics applications. Scope Covered topics include (1) a brief introduction to healthcare or biomedical blockchain applications and the benefits to adopt blockchain; (2) a description of key features of underlying blockchain platforms in healthcare applications; (3) development of a method for systematic review of technology, based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement, to investigate blockchain platforms for healthcare and medicine applications; (4) a review of 21 healthcare-related technical features of 10 popular blockchain platforms; and (5) a discussion of findings and limitations of the review.

scholarly journals Statements, Recommendations, Proposals, Guidelines, Checklists and Scales Available for Reporting Results in Biomedical Research and Quality of Conduct. A Systematic Review

2020 ◽  
Vol 38 (3) ◽  
pp. 774-786
Author(s):  
Tamara Otzen ◽  
Carlos Manterola ◽  
Mirian Mora ◽  
Guissella Quiroz ◽  
Paulina Salazar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Biomedical Research

BIOMEDICAL RESEARCH PAYS OFF

PEDIATRICS ◽  
1977 ◽  
Vol 59 (6) ◽  
pp. 832-832
Author(s):  
J. H. Comroe ◽  
R. D. Dripps
Keyword(s):  
Research And Development ◽  
Biomedical Research ◽  
Basic Research ◽  
The Other ◽  
Human Diseases ◽  
Different Types ◽  
Living Organisms

Our analysis showed . . . 41% of all work judged to be essential for later clinical advance was not clinically oriented at the time it was done. The scientists responsible for these key articles sought knowledge for the sake of knowledge. . . . Our data show that clinical advance requires different types of research and development and not one to the exclusion of the other. . . . Our data compel us to conclude (1) that a generous portion of the nation's biomedical research dollar should be used to identify and then provide long term support for creative scientists whose main goal is to learn how living organisms function, without regard to the immediate relation of their research to specific human diseases; and (2) that basic research, as we have defined it, pays off in terms of key discoveries almost twice as handsomely as other types of research and development combined.

scholarly journals Policy and Economic Considerations for the Provision of Global Public Goods: Biomedical Research and Development

2017 ◽  
Vol 83 (1) ◽  
pp. 112
Author(s):  
C.L. Anderson ◽  
T. Reynolds ◽  
P. Biscaye ◽  
J. Knauer ◽  
C. O'Brien-Carelli
Keyword(s):  
Research And Development ◽  
Public Goods ◽  
Biomedical Research ◽  
Global Public Goods ◽  
Economic Considerations

scholarly journals Botanical biopesticides: research and development trends, a focus on the Annonaceae family

2019 ◽  
Vol 13 (3) ◽  
pp. 371-383
Author(s):  
Ana Isabel Giraldo-Rivera ◽  
Gloria-Edith Guerrero-Alvarez
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Research And Development ◽  
Plant Extracts ◽  
Subsequent Development ◽  
Review Of The Literature ◽  
Development Trends ◽  
Market Trends ◽  
Pesticide Regulation ◽  
Botanical Extracts

This document analyzed research and development trends related to chemical, biological and economical biopesticides based on plant extracts, with emphasis on the Annonaceae family. A systematic review of the literature between 1947 and 2018 was done with an advance search equation in a specialized data base. This paper contains the development of plant bio pesticides, their modes of action, the more prominent families according to their bioactivity and the secondary metabolites that exert control over pests that are significant in agriculture and public health. The dynamics of publications, at the national and international levels, were identified, along with the countries that lead research, patents assigned in the last 20 years, market trends and bio pesticide regulation. The reviewed research is relevant to bioprospecting plant extracts with potential insecticidal activity and to the subsequent development of biocides using botanical extracts; the Annonaceae family is promising.

scholarly journals Implementation of Electronic Informed Consent in Biomedical Research and Stakeholders’ Perspectives: Systematic Review (Preprint)

2020 ◽  
Author(s):  
Evelien De Sutter ◽  
Drieda Zaçe ◽  
Stefania Boccia ◽  
Maria Luisa Di Pietro ◽  
David Geerts ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mixed Methods ◽  
User Interface ◽  
Informed Consent ◽  
Systematic Reviews ◽  
Biomedical Research ◽  
Cross Sectional ◽  
Research Participants ◽  
Stakeholder Groups ◽  
Multiple Stakeholder

BACKGROUND Informed consent is one of the key elements in biomedical research. The introduction of electronic informed consent can be a way to overcome many challenges related to paper-based informed consent; however, its novel opportunities remain largely unfulfilled due to several barriers. OBJECTIVE We aimed to provide an overview of the ethical, legal, regulatory, and user interface perspectives of multiple stakeholder groups in order to assist responsible implementation of electronic informed consent in biomedical research. METHODS We conducted a systematic literature search using Web of Science (Core collection), PubMed, EMBASE, ACM Digital Library, and PsycARTICLES. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were used for reporting this work. We included empirical full-text studies focusing on the concept of electronic informed consent in biomedical research covering the ethical, legal, regulatory, and user interface domains. Studies written in English and published from January 2010 onward were selected. We explored perspectives of different stakeholder groups, in particular researchers, research participants, health authorities, and ethics committees. We critically appraised literature included in the systematic review using the Newcastle-Ottawa scale for cohort and cross-sectional studies, Critical Appraisal Skills Programme for qualitative studies, Mixed Methods Appraisal Tool for mixed methods studies, and Jadad tool for randomized controlled trials. RESULTS A total of 40 studies met our inclusion criteria. Overall, the studies were heterogeneous in the type of study design, population, intervention, research context, and the tools used. Most of the studies’ populations were research participants (ie, patients and healthy volunteers). The majority of studies addressed barriers to achieving adequate understanding when using electronic informed consent. Concerns shared by multiple stakeholder groups were related to the security and legal validity of an electronic informed consent platform and usability for specific groups of research participants. CONCLUSIONS Electronic informed consent has the potential to improve the informed consent process in biomedical research compared to the current paper-based consent. The ethical, legal, regulatory, and user interface perspectives outlined in this review might serve to enhance the future implementation of electronic informed consent. CLINICALTRIAL PROSPERO International Prospective Register of Systematic Reviews CRD42020158979; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=158979

scholarly journals A systematic review protocol of medical and clinical research landscapes and quality in Malaysia and Indonesia [REALQUAMI]

2020 ◽  
Author(s):  
Boon How Chew ◽  
Shaun Wen Huey Lee ◽  
Poh Ying Lim ◽  
Soo Huat Teoh ◽  
Aneesa Abdul Rashid ◽  
...  
Keyword(s):  
Systematic Review ◽  
Biomedical Research ◽  
Phase 1 ◽  
Research Performance ◽  
Health Conditions ◽  
Research Quality ◽  
Independent Effect ◽  
Responsible Conduct Of Research ◽  
And Performance

Abstract Background Research landscapes and quality may change in many ways. Much research waste has been increasingly reported. Poorly conducted clinical and biomedical researches are detrimental to the health of the people and healthcare performance with misleading clinical evidence. Efforts to improve research performance will need good data on the profiles and performance of past research. This systematic review aims to describe the characteristics and examine the quality of clinical and biomedical research in Malaysia and Indonesia. Methods A search will be conducted in PubMed, EMBASE, CINAHL and PsycINFO to identify for published clinical and biomedical research from 1962 to 2019 from Malaysia and/or Indonesia. Additional search will also be conducted in MyMedR (Malaysian only). Studies found will be independently screened by a team of reviewers, relevant information will be extracted and the quality of articles will be assessed. In Phase 1, the characteristics of the research including the profiles of the researchers and the journals in which they are published will be reported descriptively. In Phase 2, a research quality screening tool will be validated to assess the research quality based on three domains of relevance, the credibility of the methods and usefulness of the results. Associations between the research characteristics and quality will be analysed. The independent effect of each of the determinant will be quantified in multivariable regression analysis. Longitudinal trends of the research characteristics, health conditions studied and settings, among others will be explored. Discussion Results of this study will serve as the 'baseline' data for future evaluation and within the country and between countries comparison. This review may also provide informative results to stakeholders of the evolution of research conduct and performance from the past until now. The longitudinal and prospective trends of the research characteristics and quality could provide suggestions on improvement initiatives. Additionally, information on health conditions, research settings, and whether they are over- or under-studied may help future prioritization of research initiatives and resources. Registration: CRD42020152907 (PROSPERO) and https://osf.io/w85ce (Open Science Framework’s registry for Research on the Responsible Conduct of Research).

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