Bacteriological profile and antimicrobial sensitivity pattern of endotracheal tube aspirates of patients admitted in ICU

Pediatric urinary tract infections (UTI) are associated with significant morbidity and potential long term complication like extensive renal scarring leading to end stage renal disease. Prompt diagnosis and early initiation of treatment is necessary to prevent long term complications. Knowledge about bacteriological profile of pediatric urinary tract infections and their antimicrobial sensitivity pattern is helpful for initiation of empirical antibiotic treatment. The aim of this study was to identify the causative bacteria and antimicrobial sensitivity pattern of community acquired UTI in children attending outpatient department of a tertiary level hospital of Bangladesh. This was a cross-sectional study conducted in pediatric outpatient department of Rajshahi Medical College Hospital, Bangladesh over 6 month period from 1st January 2017 to 30th June 2017. Children aged < 12 year who presented with clinical features suggestive of urinary tract infection were subjected for urinary routine and microscopic examination and culture. Colony counts of the culture positive cases were done and antibiotic sensitivity and resistance patterns were studied. Samples with colony count of ≥ 105 CFU/ml were considered significant. Among the 134 clinically suspected cases significant bacteriuria was found in 81 (60.45%) children. Escherichia coli was the most common isolate (74.1%) followed by Proteus (9.8%), Klebsiella spp. (8.6%), Pseudomonas (6.2%) and Staphylococcus saprophyticus (1.2%). E. coli was found to be highly sensitive to imipenem, amikacin, nitrofurantoin and ciprofloxacin. Klebsiella showed good sensitivity against ciprofloxacin and imipenem whereas proteus, Pseudomonas and Staphylococcus saprophyticus showed sensitivity against imipenem, amikacin and ciprofloxacin. Increased resistance was noted against the commonly used empirical antibiotics such as cephradin, cefuroxime, cefixime, ceftriaxone and co-trimoxazole. Therefore, selection of empirical therapy should be based on local bacteriological profile and their antimicrobial sensitivity pattern. TAJ 2020; 33(2): 27-31

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Bacteriological Profile and Antimicrobial Sensitivity Pattern of Blood Culture Isolates

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2020/434 ◽

2020 ◽

Vol 7 (38) ◽

pp. 2092-2095

Author(s):

Pradheep Kumar Kokku ◽

Priyadarshini T ◽

Sravanthi C.H

Keyword(s):

Blood Culture ◽

Antimicrobial Sensitivity ◽

Bacteriological Profile ◽

Sensitivity Pattern

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Bacteriological Profile and Antimicrobial Sensitivity Pattern of Neonatal Sepsis

The Journal of Sylhet Women’s Medical College ◽

10.47648/jswmc2021v1102-05 ◽

2021 ◽

Vol 11 (Number 2) ◽

pp. 44-51

Author(s):

Farhana Jaya Chowdhury ◽

A.H.M Khairul Bashar ◽

Md Shahabuddin ◽

Murshida Afruz ◽

Fahim Ara Jenny

Keyword(s):

Blood Culture ◽

Positive Blood Culture ◽

Neonatal Sepsis ◽

Klebsiella Pneumonia ◽

Gram Positive ◽

Gram Negative ◽

Antimicrobial Sensitivity ◽

Bacteriological Profile ◽

Sensitivity Pattern ◽

Neonatal Ward

Introduction: Neonatal sepsis (NS) is one of the important causesof neonatal morbidity anddeath in neonatal ward and neonatal medical care unit,especiallyin emergent nations. Frequent monitoring on pathogens with recent updates and their antimicrobial sensitivity pattern is compulsory for more satisfactory management. Methods: This cross sectionalstudy was outlined to evaluate the bacteriological profile and antimicrobialsensitivity pattern of NS in neonatal ward and neonatal intensive care unit (NICU)of Sylhet Women’s Medical College and Hospital, Sylhet, Bangladeshfrom October 2019 to December 2020. Blood samples from 90 clinically suspected neonatal sepsis cases were accumulated and processed in the microbiological protocol and their antimicrobial sensitivity pattern were determined. Results: Among the90 cases, two third (61, 67.78%) showed positive blood culture. Among the positive blood culture, 38(62.29%) were gram positive isolates and gram negative isolates were 23(37.7%). This study showed Staphylococcus aureuswas the most common organism (59.01%) followed by Escherichia coli (E. Coli)(27.87%), Klebsiella pneumonia (9.87%) and Streptococcus pneumonia (3.28%) among the isolates. Gram positive isolates were highly reactive to Amikacin and Amoxicillin and Clavulenic acid whereas gram negative isolates were highly reactive to Gentamicin and Meropenem. Conclusion: Gram positive organism are the predominant source of NS which was highlighted in our study,though gram negative organism also plays an important role in the mortality cause by neonatal sepsis.

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