Cognitive impairment among Hindi mental state examination positive community-dwelling rural older adults

Our study examined the association between chronotype, daily physical activity, and the estimated risk of dementia in 170 community-dwelling older adults. Chronotype was assessed with the Horne–Östberg Morningness–Eveningness Questionnaire (MEQ). Daily physical activity (of over 3 METs) was measured with a tri-axial accelerometer. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to measure the estimated risk of dementia. The evening chronotype, low daily physical activity, and dementia were positively associated with each other. The participants with low physical activity alongside evening preference had 3.05 to 3.67 times higher estimated risk of developing dementia, and participants with low physical activity and morning preference had 1.95 to 2.26 times higher estimated risk than those with high physical activity and morning preference. Our study design does not infer causation. Nevertheless, our findings suggest that chronotype and daily physical activity are predictors of the risk of having dementia in older adults aged 70 years and above.

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Normalisation du Mini-Mental State Examination (MMSE) chez les Québécois francophones âgés de 65 ans et plus et résidant dans la communauté

Canadian Journal on Aging / La Revue canadienne du vieillissement ◽

10.1017/s0714980809990171 ◽

2009 ◽

Vol 28 (4) ◽

pp. 347-357 ◽

Cited By ~ 16

Author(s):

Carol Hudon ◽

Olivier Potvin ◽

Marie-Christine Turcotte ◽

Catherine D’Anjou ◽

Micheline Dubé ◽

...

Keyword(s):

Older Adults ◽

Mental State ◽

Normative Data ◽

Mini Mental State Examination ◽

Education Level ◽

Community Dwelling ◽

Education Levels ◽

French Speaking ◽

And Gender ◽

State Examination

ABSTRACTThis study was aimed at providing normative data for the Mini-Mental State Examination (MMSE). The norms were built from a sample (n = 2409) of community-dwelling French speaking residents from Québec aged 65 and older. The analyses indicated that socio-demographic variables such as education level, age, and gender of individuals influenced significantly the scores of older adults on the MMSE. More precisely, MMSE scores increased with education level and decreased with age. Moreover, women had significantly higher scores than men. On this basis, distinct tables of normative data were produced for women and men. In each table, the MMSE scores corresponding to percentiles 5, 10, 15 and 50 were identified according to four age categories and three education levels. Overall, the use of the present normative data by clinicians will improve their accuracy in detecting cognitive impairment in older adults from Québec.

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Utility of a modified mini-mental state examination with extended delayed recall in screening for mild cognitive impairment and dementia among community dwelling elders

International Journal of Geriatric Psychiatry ◽

10.1002/(sici)1099-1166(200005)15:5<434::aid-gps137>3.0.co;2-2 ◽

2000 ◽

Vol 15 (5) ◽

pp. 434-440 ◽

Cited By ~ 34

Author(s):

David A. Loewenstein ◽

Warren W. Barker ◽

Dylan G. Harwood ◽

Cheryl Luis ◽

Amarilis Acevedo ◽

...

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Mental State ◽

Mini Mental State Examination ◽

Community Dwelling ◽

Delayed Recall ◽

State Examination

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Mini-Mental State Examination performance in frail, pre-frail, and non-frail community dwelling older adults in Ermelino Matarazzo, São Paulo, Brazil

International Psychogeriatrics ◽

10.1017/s1041610212000907 ◽

2012 ◽

Vol 24 (11) ◽

pp. 1725-1731 ◽

Cited By ~ 57

Author(s):

Cláudia Rodrigues Monteiro Macuco ◽

Samila Satler Tavares Batistoni ◽

Andrea Lopes ◽

Meire Cachioni ◽

Deusivânia Vieira da Silva Falcão ◽

...

Keyword(s):

Older Adults ◽

Mental State ◽

Mini Mental State Examination ◽

Sao Paulo ◽

Community Dwelling ◽

Cardiovascular Health Study ◽

São Paulo ◽

Frail Older Adults ◽

Community Dwelling Older Adults ◽

State Examination

ABSTRACTBackground: Frailty in older adults is a multifactorial syndrome defined by low metabolic reserve, less resistance to stressors, and difficulty in maintaining organic homeostasis due to cumulative decline of multiple physiological systems. The relationship between frailty and cognition remains unclear and studies about Mini-Mental State Examination (MMSE) performance and frailty are scarce. The objective was to examine the association between frailty and cognitive functioning as assessed by the MMSE and its subdomains.Methods: A cross-sectional population-based study (FIBRA) was carried out in Ermelino Matarazzo, a poor subdistrict of the city of São Paulo, Brazil. Participants were 384 community dwelling older adults, 65 years and older who completed the MMSE and a protocol to assess frailty criteria as described in the Cardiovascular Health Study (CHS).Results: Frail older adults had significantly worse performance on the MMSE (p < 0.001 for total score). Linear regression analyses showed that the MMSE total score was influenced by age (p < 0.001), education (p < 0.001), family income (p < 0.001), and frailty status (p < 0.036). Being frail was associated more significantly with worse scores in Time Orientation (p < 0.004) and Immediate Memory (p < 0.001).Conclusions: Our data suggest that being frail is associated with worse cognitive performance, as assessed by the MMSE. It is recommended that the assessment of frail older adults should include the investigation of their cognitive status.

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Comparing the Mini-Mental State Examination and the modified Mini-Mental State Examination in the detection of mild cognitive impairment in older adults

International Psychogeriatrics ◽

10.1017/s1041610218001023 ◽

2018 ◽

Vol 31 (5) ◽

pp. 693-701 ◽

Cited By ~ 6

Author(s):

Ryan Van Patten ◽

Karysa Britton ◽

Geoffrey Tremont

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Mental State ◽

Normative Data ◽

Mini Mental State Examination ◽

Area Under The Curve ◽

Neuropsychological Evaluations ◽

Composite Scores ◽

State Examination

ABSTRACTObjectives:To show enhanced psychometric properties and clinical utility of the modified Mini-Mental State Examination (3MS) compared to the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI).Design:Psychometric and clinical comparison of the 3MS and MMSE.Setting:Neuropsychological clinic in the northeastern USA.Participants:Older adults referred for cognitive concerns, 87 of whom were cognitively intact (CI) and 206 of whom were diagnosed with MCI.Measurements:The MMSE, the 3MS, and comprehensive neuropsychological evaluations.Results:Both instruments were significant predictors of diagnostic outcome (CI or MCI), with comparable odds ratios, but the 3MS explained more variance and showed improved classification accuracies relative to the MMSE. The 3MS also demonstrated greater receiver operating characteristic area under the curve values (0.85, SE = 0.02) compared to the MMSE (0.74, SE = 0.03). Scoring lower than 95/100 on the 3MS suggested MCI, while scoring lower than 28/30 on the MMSE suggested MCI. Additionally, compared to the MMSE, the 3MS shared more variance with neuropsychological composite scores in Language and Memory domains but not in Attention, Visuospatial, and Executive domains. Finally, 65.5% MCI patients were classified as impaired (scoring ≤1 SD below the mean) using 3MS normative data, compared to only 11.7% of patients who were classified as impaired using MMSE normative data.Conclusions:Broadly speaking, our data strongly favor the widespread substitution of the MMSE with the 3MS in older adults with concerns for cognitive decline.

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Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults

BMC Geriatrics ◽

10.1186/s12877-015-0103-3 ◽

2015 ◽

Vol 15 (1) ◽

Cited By ~ 183

Author(s):

Paula T. Trzepacz ◽

◽

Helen Hochstetler ◽

Shufang Wang ◽

Brett Walker ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Mental State ◽

Cognitive Assessment ◽

Mini Mental State Examination ◽

Montreal Cognitive Assessment ◽

State Examination

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Probable sarcopenia is associated with cognitive impairment among community-dwelling older adults: results from the FIBRA study

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x-anp-2020-0186 ◽

2021 ◽

Vol 79 (5) ◽

pp. 376-383

Author(s):

Gabriela Cabett Cipolli ◽

Ivan Aprahamian ◽

Flávia Silva Arbex Borim ◽

Deusivania Vieira Silva Falcão ◽

Meire Cachioni ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Grip Strength ◽

Sex Education ◽

Leisure Time Physical Activity ◽

Community Dwelling ◽

Clock Drawing Test ◽

Community Dwelling Older Adults ◽

The Relationship ◽

State Examination

ABSTRACT Background: The link between sarcopenia and cognitive impairment has not yet been thoroughly evaluated, especially among older adults. Objective: To evaluate the relationship between probable sarcopenia and cognitive impairment among community-dwelling older adults in two Brazilian cities. Methods: Probable sarcopenia was assessed using the EWGSOP2 (2018) criteria. Thus, participants were classified as probably having sarcopenia if they had SARC-F (Strength, Assistance in walking, Rise from a chair, Climb stairs and Falls) ≥4 points and low grip strength. Cognitive function was evaluated through the Mini-Mental State Examination (MMSE), verbal fluency (VF) and clock drawing test (CDT). Results: In a sample of 529 older adults (mean age 80.8±4.9 years; mean education 4.2±3.67 years; 70.1% women), 27.3% of the participants had SARC-F≥4, 38.3% had low grip strength and 13.6% were classified as probable sarcopenia cases. After adjusting for possible confounders (age, sex, education, depression, diabetes, hypertension, leisure-time physical activity and obesity), probable sarcopenia was found to be associated with impairment in the MMSE (OR 2.52; 95%CI 1.42‒4.47; p=0.002) and in VF (OR 2.17; 95%CI 1.17‒4.01; p=0.014). Low grip strength was found to be associated with impairment in the MMSE (OR 1.83; 95%CI 1.18‒2.82; p=0.006) and in the CDT (OR 1.79; 95%CI 1.18‒2.73; p=0.006). SARC-F scores were found to be associated with impairment in the MMSE (OR 1.90; 95%CI 1.18‒3.06; p=0.008). Conclusion: The results suggested that probable sarcopenia and its components present a significant association with cognitive deficits among community-dwelling older adults. Future longitudinal studies will further explore the causal relationship.

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Mini-Mental State Examination sentence writing among community-dwelling elderly adults in Brazil: text fluency and grammar complexity

International Psychogeriatrics ◽

10.1017/s104161021200097x ◽

2012 ◽

Vol 24 (11) ◽

pp. 1732-1737 ◽

Cited By ~ 9

Author(s):

Anita Liberalesso Neri ◽

Lia Lopes Ongaratto ◽

Mônica Sanches Yassuda

Keyword(s):

Cognitive Impairment ◽

Mental State ◽

Mini Mental State Examination ◽

Cognitive Status ◽

Community Dwelling ◽

Cognitively Impaired ◽

Simple Sentence ◽

Textual Production ◽

Probabilistic Sample ◽

State Examination

ABSTRACTBackground: In normal aging, the decrease in the syntactic complexity of written production is usually associated with cognitive deficits. This study was aimed to analyze the quality of older adults' textual production indicated by verbal fluency (number of words) and grammatical complexity (number of ideas) in relation to gender, age, schooling, and cognitive status.Methods: From a probabilistic sample of community-dwelling people aged 65 years and above (n = 900), 577 were selected on basis of their responses to the Mini-Mental State Examination (MMSE) sentence writing, which were submitted to content analysis; 323 were excluded as they left the item blank or performed illegible or not meaningful responses. Education adjusted cut-off scores for the MMSE were used to classify the participants as cognitively impaired or unimpaired. Total and subdomain MMSE scores were computed.Results: 40.56% of participants whose answers to the MMSE sentence were excluded from the analyses had cognitive impairment compared to 13.86% among those whose answers were included. The excluded participants were older and less educated. Women and those older than 80 years had the lowest scores in the MMSE. There was no statistically significant relationship between gender, age, schooling, and textual performance. There was a modest but significant correlation between number of words written and the scores in the Language subdomain.Conclusions: Results suggest the strong influence of schooling and age over MMSE sentence performance. Failing to write a sentence may suggest cognitive impairment, yet, instructions for the MMSE sentence, i.e. to produce a simple sentence, may limit its clinical interpretation.

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Helicobacter pylori, Vascular Risk Factors and Cognition in U.S. Older Adults

Brain Sciences ◽

10.3390/brainsci9120370 ◽

2019 ◽

Vol 9 (12) ◽

pp. 370 ◽

Cited By ~ 1

Author(s):

Cárdenas ◽

Boller ◽

Román

Keyword(s):

Older Adults ◽

Helicobacter Pylori ◽

Risk Factor ◽

Cognitive Impairment ◽

Confidence Interval ◽

Mental State ◽

Mini Mental State Examination ◽

Helicobacter Pylori Infection ◽

H Pylori ◽

State Examination

Previous studies suggested that Helicobacter pylori infection could be a risk factor for stroke, dementia, and Alzheimer’s disease (AD). The authors examined data from participants, 60 years old and older in the Third National Health and Nutrition Examination Survey (NHANES-III) to assess the relation between Helicobacter pylori infection and results of the Mini-Mental State Examination (n = 1860) using logistic regression analysis controlling for age, gender, race/ethnicity, education, poverty and history of medically diagnosed diabetes. Moreover, we examined performance on the digit-symbol substitution test (DSST) of 1031 participants in the 1999–2000 NHANES according to their H. pylori infection status controlling for potential confounders using multiple linear regression analyses. In 1988–1991, older adults infected with CagA strains of H. pylori had a 50% borderline statistically significant increased level of cognitive impairment, as measured by low Mini-Mental State Examination (MMSE) scores (age–education adjusted prevalence ratio: 1.5; 95% confidence interval: 1.0, 2.0). In 1999–2000, older US adults infected with H. pylori scored 2.6 fewer points in the DSST than those uninfected (mean adjusted difference: −2.6; 95% confidence interval −5.1, −0.1). The authors concluded that H. pylori infection might be a risk factor for cognitive decline in the elderly. They also found that low cobalamin and elevated homocysteine were associated with cognitive impairment.

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