scholarly journals Schwannoma of head-and-neck region: A clinical chameleon – Report of two cases occurring at rare sites with unusual clinical manifestations

2020 ◽  
Vol 24 (1) ◽  
pp. 164
Author(s):  
Meenakshi Rao ◽  
Mayank Kumar ◽  
Poonam Elhence ◽  
Darwin Kaushal ◽  
Taruna Yadav
Author(s):  
Josué D. Ramírez Esquivel

La granulomatosis con poliangeitis es una enfermedad poco común, cuya incidencia anual es de 8-10 casos por millón de personas, causada por una reacción autoinmune inusual asociada a la elevación de los anticuerpos anticitoplasma de neutrófilos (ANCA) que ocasionan vasculitis de pequeños vasos e inflamación granulomatosa. Estas reacciones ocasionan síntomas que usualmente comienzan de manera localizada, afectando la cabeza y el cuello, que progresan a una afectación sistémica con pobre pronóstico, sin embargo en ocasiones estos pueden ser pasados por altos y atrasar su diagnóstico. El artículo se  centra en mencionar las manifestaciones clínicas más importantes en la cabeza y el cuello. El diagnóstico es difícil y se basa en las manifestaciones clínicas, asociadas a un análisis histopatológico y positividad de los ANCA. El tratamiento temprano ayuda a mejorar el pronóstico de esta, y se necesita de un equipo multidisciplinario para el diagnóstico y tratamiento de esta enfermedad, para así lograr una remisión y prevenir la mayor cantidad de efectos adversos de los tratamientos.  Granulomatosis with polyangiitis is a rare disease, with an anual incidence of 8-10 cases per million people, it´s caused by an unusual autoimmune reaction associated with antineutrophil cytoplasmic antibodies (ANCA), producing small-vessel vasculitis and granulomatous inflammation. These reactions result in symptoms, usually localized starting in the head and neck region, progressing to a systemic form with a poor prognosis, however, some of these symptoms can be overlooked and delay the diagnosis. This article centers in mentioning the most important clinical manifestations in the head and neck. Diagnosis is difficult, and it’s based on clinical manifestations associated with histopathological analysis and ANCA positivity. Early treatment helps improving the prognosis, and a multi-disciplinary cooperation is needed for the diagnosis and treatment of this disease, to adequately achieve the remission and to prevent most of the adverse effects of the treatments.


2021 ◽  
Vol 9 (1) ◽  
pp. 140
Author(s):  
Santosh Kumar Swain ◽  
Ishwar Chandra Behera ◽  
Pragnya Paramita Jena

The majority of cases of actinomycosis are of odontogenic origin and related to the perimandibular region with other sites of primary actinomycosis in the head and neck region include the tongue, paranasal sinuses, middle ear, larynx, lacrimal passage, and thyroid gland. Actinomycosis is an uncommon infection caused by Actinomyces species, facultative anaerobic bacteria that are part of the normal flora in the oropharynx, gastrointestinal tract, and female genital tract. The risk factors for actinomycosis in the pediatric age group are dental caries, trauma, debilitation, and poorly controlled diabetes mellitus. The pathogenesis of the actinomycosis in the head and neck region is often unclear. The hallmark of actinomycosis is the spread of infection which fails to respect the tissue or fascial planes. The organism causing actinomycosis is often difficult to isolate from culture and the differential diagnosis is extensive which prompts clinicians to name the actinomycosis the masquerader of the head and neck area. This clinical entity in pediatric patients may mimic malignancy or granulomatous disease in the head and neck region. Clinicians must be aware of typical presentations of actinomycosis in the head and neck region. Bacterial cultures and histopathological study are the cornerstones of the diagnosis of actinomycosis, however, particular conditions are needed to find the exact diagnosis. The treatment of actinomycosis includes a combination of surgery and antibiotic therapy. Surgery is an important adjunctive to medical therapy in patients with extensive lesions of actinomycosis. Actinomyces species are uniformly susceptible to penicillin. This review article discusses the etiopathology, epidemiology, clinical manifestations, diagnosis, and current treatment of the actinomycosis in the head and neck region of pediatric patients.


2020 ◽  
pp. 136-141
Author(s):  
Lelani Reniarti ◽  
Nur Fatharani ◽  
Nur Suryawan

Background: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcomas (STS) in children. Even though the survival rate has increased, the mortality rates remain significantly higher in developing countries due to delay in diagnosis contributed by its diverse and clinical manifestations. This study aimed to describe the clinical characteristics of RMS patients at the Department of Child Health, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. Methods: A descriptive cross-sectional retrospective study was conducted using a total sampling method on medical records of RMS patients aged ≤ 18-year-old during a 4-year period (2015-2018). Data on patient demographics, clinical manifestations, biopsy procedure, histopathological subtype, tumor size, primary site, pre-treatment staging, and treatment were reviewed and presented. Results: Of 30 data retrieved, male (57%), aged 1 to 5-year-old (47%), and diagnosed through open biopsy (63%) comprised the majority of the patients. More than half of the patients came with advanced stage of the disease (80%) and were treated with chemotherapy (83%). Most RMS patients had a tumor located in the head and neck region (40%) with a size of >5 cm (70%) and embryonal subtypes (43%). The remaining patients experienced alveolar subtype (17%), spindle cell subtype (13%), and unknown subtype (27%) of RMS. Conclusion: Children with a tumor in the head and neck region should be suspected as rhabdomyosarcoma, as there are various clinical characteristics of RMS in children found in this study.


Author(s):  
Prasetyanugraheni Kreshanti ◽  
Nandya Titania Putri ◽  
Valencia Jane Martin ◽  
Chaula Luthfia Sukasah

Author(s):  
Gonca Cinkara ◽  
Ginger Beau Langbroek ◽  
Chantal M. A. M. van der Horst ◽  
Albert Wolkerstorfer ◽  
Sophie E. R. Horbach ◽  
...  

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Geoffrey Williams ◽  
Carlos Neblett ◽  
Jade Arscott ◽  
Sheena McLean ◽  
Shereika Warren ◽  
...  

Abstract Kimura disease (KD) is a chronic, inflammatory, benign disorder endemic to Asia that typically manifests as a triad of painless masses in the head and neck region, elevated eosinophils and serum immunoglobulin. It usually affects young men in their second and third decades of life and is rarely seen outside of the orient. This is a report of a case of KD in a young man of African descent who presented with a cheek mass. KD was not included in our differential diagnosis, and this report highlights the need to consider this entity, which can be easily missed due to its rarity in the Western world. There is no cure for the disease, and management includes medical and surgical modalities, but local recurrence or relapse is not uncommon.


2019 ◽  
Vol 52 (4) ◽  
pp. 268-271
Author(s):  
Pinar Gulmez Cakmak ◽  
Gülsüm Akgün Çağlayan ◽  
Furkan Ufuk

Abstract Primary extranodal lymphoma is defined as a lymphoma at a solitary extranodal site, with or without involvement of the lymph nodes. The clinical and radiological features of extranodal lymphoma have been documented in recent studies. In this pictorial essay, we reviewed imaging findings of extranodal lymphoma in the head and neck region.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Han-Gyeol Yeom ◽  
Jung-Hoon Yoon

Abstract Background Concomitant cemento-osseous dysplasia (COD) and aneurysmal bone cyst (ABC) are rare in the head and neck region. In our search of the English language literature, we found only one case report describing the simultaneous occurrence of COD and ABC in the head and neck region. Here, we report a case of COD associated with ABC. Further, we performed a systematic search of the literature to identify studies on patients with COD associated with nonepithelial lined cysts of the jaws. Case presentation The patient was a 32-year-old woman who was referred from a private dental clinic because of a cystic lesion below the mandibular right first molar. She had no pain or significant systemic disease. After performing panoramic radiography and cone-beam computed tomography, the imaging diagnosis was COD with a cystic lesion, such as ABC or solitary bone cyst. Excisional biopsy was performed, which revealed concomitant COD and ABC. Conclusion This case of ABC associated with COD provides insight for the diagnostic process of radiographically mixed lesions with cystic changes.


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