Spectrum of 18F-FDG PET/CT extranodal findings in lymphoma

Background Extranodal lymphoma can be the primary presentation or secondary to systemic involvement of lymphoma. Positron emission tomography with computer tomography (FDG-PET/CT) is useful in detecting extranodal sites during staging, treatment response assessment or recurrence detection in patients with lymphoma. Objective To demonstrate the PET/CT imaging appearances of extranodal lymphoma. Methods A descriptive retrospective study, conducted at Ain Shams University hospitals on 40 Patients with different types of lymphoma enrolled in this study over a period of six months starting from December 2018 to May 2019 at Ain shams university hospitals. Results The 40 patients involved in this study showed 58 extranodal lesions in 19 different extra-lymphatic sites, where the most frequently impacted sites were bone and bone marrow (20.7%) while supraglottic larynx, oesophagus and para vertebral sites are the least affected (1.7% each). Conclusion Knowledge of the imaging appearances of extranodal lymphoma can aid in the differential diagnosis of mass lesions encountered in tissues throughout the body on PET/CT.

Primary conjunctival peripheral T-cell lymphoma: a case report.

Primary ocular adnexal T-cell extranodal lymphoma are uncommon and carry a particularly poor prognosis. It represents 1%–2% of all NHL. Because of its rarity, we want to show to the medical community our experience about primary conjunctival T cell lymphoma by reviewing literature and discussing our case.

Primary Extranodal Non-Hodgkin Lymphomas: A First Tertiary Care Experience from Punjab, North India

Background Primary extranodal lymphomas are less frequently encountered and difficult to diagnose in routine practice. The histopathological and immunohistochemical studies are essential in addition to clinical details to diagnose. The incidence is varied in different parts of India along with variation in histopathological spectrum. Methodology The clinical features and histopathological findings of patients diagnosed with primary extranodal lymphoma over 3-year period were retrieved from archives of pathology department and analyzed. Results During the 3-year study period, a total of 135 cases of non-Hodgkin lymphomas were evaluated, and of these, 41.4% (56/135) of cases presented with primary extranodal involvement. The mean age of primary extranodal lymphoma presentation was 61.3 ± 17.5 with M:F ratio of 1:1.1 Most common extranodal site involved was gastrointestinal tract 32.1%, 18/56 (small intestine [17.8%, 10 cases] and large intestine [8.9%, 5 cases]). Non-Hodgkin lymphomas of B cell type were the predominant subtype (48/56, 85.7%), while 8/56 (14.2%) cases were of T cell lineage. Of the B cell non-Hodgkin lymphoma diffuse, large B cell lymphoma was the predominant subtype constituting ~83.3% (40/48). Conclusion Primary extranodal lymphomas exhibit varied histomorphological and clinical presentation. The present study is first such analysis from Punjab that intends to compare with studies from other parts of India.